Results 41 to 50 of about 186,531 (283)

The association between beta-blocker use and chronic obstructive pulmonary disease risk, severity, and exacerbation

Medical Journal of Babylon, 2021
Background: There is controversy about the role of beta-blockers in the number of acute exacerbations in patients with chronic obstructive pulmonary disease (COPD).
Hemin Khalid Saber
doaj   +1 more source

Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for CYP2D6, ADRB1, ADRB2, ADRA2C, GRK4, and GRK5 Genotypes and Beta-Blocker Therapy

Clinical pharmacology and therapy
Beta‐blockers are widely used medications for a variety of indications, including heart failure, myocardial infarction, cardiac arrhythmias, and hypertension.
J. Duarte, Cameron D. Thomas, Craig R. Lee, Rachel Huddart, José A. G. Agúndez, Jordan F. Baye, A. Gaedigk, Teri E. Klein, D. Lanfear, Andrew A. Monte, Mohamed Nagy, M. Schwab, C. M. Stein, C. R. Uppugunduri, Ron H. N. Schaik, Roseann S. Donnelly, K. Caudle, Jasmine A. Luzum   +17 more
semanticscholar   +1 more source

Clinical toxicology of beta‐blocker overdose in adults

Basic & Clinical Pharmacology & Toxicology, 2019
Beta‐blocker overdose is potentially harmful due to the strong blood pressure‐lowering and heart rate‐lowering effects. However, conflicting data exist as to their differential toxicity, single‐substance exposures and the effect of co‐exposure with ...
M. Lauterbach
semanticscholar   +1 more source

Efficacy and Tolerability of Travoprost 0.004%/Timolol 0.5% Fixed-Dose Combination for the Treatment of Primary Open-Angle Glaucoma or Ocular Hypertension Inadequately Controlled with Beta-Blocker Monotherapy

Journal of Ophthalmology, 2017
Objective. To evaluate the efficacy and tolerability of travoprost 0.004%/timolol 0.5% fixed-dose combination (TTFC) in patients with open-angle glaucoma (OAG) or ocular hypertension (OHT) inadequately controlled on beta-blocker monotherapy. Methods.
Simon Fabian Lerner, Ki Ho Park, Douglas A. Hubatsch, Valeriy Erichev, Jose A. Paczka, Timothy V. Roberts   +5 more
doaj   +1 more source

The role of plasma concentrations and drug characteristics of beta‐blockers in fall risk of older persons

Pharmacology Research & Perspectives, 2023
Beta‐blocker usage is inconsistently associated with increased fall risk in the literature. However, due to age‐related changes and interindividual heterogeneity in pharmacokinetics and dynamics, it is difficult to predict which older adults are more at ...
K. J. Ploegmakers, E. P. vanPoelgeest, L. J. Seppala, S. C. vanDijk, L. C. P. G. M. deGroot, S. Oliai Araghi, N. M. vanSchoor, B. Stricker, K. M. A. Swart, A. G. Uitterlinden, R. A. A. Mathôt, N. van derVelde   +11 more
doaj   +1 more source

Comparative effectiveness of enalapril, lisinopril, and ramipril in the treatment of patients with chronic heart failure: a propensity score-matched cohort study [PDF]

, 2017
Background: Angiotensin converting enzyme inhibitors (ACEIs) are recommended as first-line therapy in patients with heart failure with reduced ejection fraction (HFrEF). The comparative effectiveness of different ACEIs is not known. Methods and results:
Agewall, Stefan, Atar, Dan, Clark, Andrew L., Cleland, John G.F., Corletto, Anna, Frankenstein, Lutz, Fröhlich, Hanna, Goode, Kevin, Grundtvig, Morten, Henning, Felix, Hole, Torstein, Katus, Hugo A., Kazmi, Syed, Schellberg, Dieter, Täger, Tobias   +14 more
core   +1 more source

Antiarrhythmic mechanisms of beta blocker therapy

Pharmacological Research, 2019
Sympathetic activity plays an important role in modulation of cardiac rhythm. Indeed, while exerting positive tropic effects in response to physiologic and pathologic stressors, β-adrenergic stimulation influences cardiac electrophysiology and can lead ...
E. Grandi, C. M. Ripplinger
semanticscholar   +1 more source

THE CHOICE OF DRUG FROM THE STANDPOINT OF EVIDENCE-BASED MEDICINE: CASE STUDY OF BETA-BLOCKERS

Рациональная фармакотерапия в кардиологии, 2016
Basic principles of beta-blockers choice strategy are presented. Attention is focused on the facts concerning the evidence base for effects of various beta-blockers on the outcomes of cardiovascular diseases.
S. Yu. Martsevich, N. P. Kutishenko, Yu. V. Lukina   +2 more
doaj   +1 more source

Evaluation of Perioperative Beta-Blockers and Factors Associated with Postoperative Atrial Fibrillation in Cardiac Surgery: A Single Center Experience

Reviews in Cardiovascular Medicine, 2023
Background: Postoperative atrial fibrillation (AF) has a complex etiology, and beta-blockers are commonly recommended for its pharmacological prevention.
Alexandra Puscas, Marius M. Harpa, Klara Brinzaniuc, Hussam Al-Hussein, Hamida Al-Hussein, Cosmin Banceu, Carmen Opris, Claudiu Ghiragosian, Sanziana Flamind, Robert Balan, Septimiu Voidazan, Horatiu Suciu   +11 more
doaj   +1 more source

Antinociceptive Effects of Intrathecal Landiolol Injection in a Rat Formalin Pain Model [PDF]

, 2012
Perioperative beta-blocker administration has recently been recommended for patients undergoing cardiac or other surgery due to the beneficial cardiovascular effects of these agents.
Itano, Yoshitaro, Kaku, Ryuji, Kanzaki, Hirotaka, Matsuoka, Yoshikazu, Mizobuchi, Satoshi, Morita, Kiyoshi, Nishie, Hiroyuki, Obata, Norihiko, Ouchida, Mamoru, Taniguchi, Arata, Tomotsuka, Naoto   +10 more
core   +1 more source