Results 51 to 60 of about 186,531 (283)
Preoperative beta-blocker in ventricular dysfunction patients: need a more granular quality metric
BMC Cardiovascular Disorders, 2021 Background The use of preoperative beta-blockers has been accepted as a quality standard for patients undergoing coronary artery bypass graft (CABG) surgery.
Hanwei Tang +5 more
doaj +1 more source
The effects of beta-blocker use on cancer prognosis: a meta-analysis based on 319,006 patients
OncoTargets and Therapy, 2018 Background Beta-blockers are antihypertensive drugs and have shown potential in cancer prognosis. However, this benefit has not been well defined due to inconsistent results from the published studies.
Zhijing Na +11 more
semanticscholar +1 more source
Medicina, 2022 Background and Objectives: Drug-related bradyarrhythmia is a well-documented major adverse event among beta-blocker users and a potential cause for hospitalization or additional interventions.
Dragoș Traian Marius Marcu +8 more
doaj +1 more source
Beta‐blocker subtypes and risk of low birth weight in newborns
The Journal of Clinical Hypertension, 2018 Beta‐blockers are one of the most commonly prescribed classes of antihypertensive medications during pregnancy. Previous studies reported an association between beta‐blocker exposure and intrauterine growth restriction. Whether some beta‐blocker subtypes
L. Duan +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Effect of visit-to-visit variation of heart rate and systolic blood pressure on outcomes in chronic systolic heart failure: results from the Systolic Heart Failure Treatment With the If Inhibitor Ivabradine Trial (SHIFT) trial [PDF]
, 2016 Background: Elevated resting heart rate (HR) and low systolic blood pressure (SBP) are related to poor outcomes in heart failure (HF). The association between visit-to-visit variation in SBP and HR and risk in HF is unknown. Methods and Results:
Borer, Jeffrey +8 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Therapeutic Advances in Gastroenterology, 2017 Background: Some studies indicate a reduced risk of serious upper gastrointestinal bleeding (UGIB) for users of beta-blockers, but the association remains to be confirmed in larger studies and characterized with respect to differences among beta-blockers.
Mette Reilev +12 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Jurnal Kedokteran Diponegoro, 2018 Latar Belakang: Gagal jantung sistolik merupakan kegagalan jantung untuk memberikan suplai darah dalam memenuhi kebutuhan metabolisme jaringan dengan hipertrofi dinding ventrikel yang memiliki output terbatas karena ejeksi yang terganggu selama sistol ...
Monica Destiani +2 more
doaj +1 more source