Results 181 to 190 of about 62,383 (266)

A Narrative Review on Nitrate-Rich Diets as Adjuncts to Antihypertensive Therapy: Enhancing Treatment Efficacy via Oxidative Stress Modulation. [PDF]

Biomedicines
Silva-Cunha M, Ceron CS, Moreno H, Tanus-Santos JE.   +3 more
europepmc   +1 more source

Glutamate Delta 1 Receptor in Synapses, Circuits, and Disease

European Journal of Neuroscience, Volume 63, Issue 3, February 2026.
This review discusses our current understanding of the structure–function, expression and roles in neural circuits of the less studied glutamate delta 1 (GluD1) receptor. Converging data suggests many unique features of GluD1 including expression at both excitatory and inhibitory synapses and binding to D‐serine and GABA.
Diane Choi, Poojashree B. Chettiar, Yoland Smith, Shashank M. Dravid   +3 more
wiley   +1 more source

Arrestins as Possible Drug Targets. [PDF]

Biomol Ther (Seoul)
Cinviz ZN, Moroni E, Sensoy O, Morra G, Gurevich VV.   +4 more
europepmc   +1 more source

The biology of PKM2 in the metabolism and senescence in diabetic kidney disease

Journal of Diabetes Investigation, Volume 17, Issue 2, Page 197-204, February 2026.
ABSTRACT Diabetic kidney disease (DKD) is one of the most common causes of chronic kidney disease that leads to end‐stage kidney disease, and its progression is closely linked to metabolic stress within renal tubular cells. Under long‐term hyperglycemia, cells shift their glucose metabolism from normal oxidative phosphorylation toward glycolysis.
Md. Imrul Kayes, Keizo Kanasaki
wiley   +1 more source

Neurotransmitters in tumors: chemical cross-talk shaping tumor progression. [PDF]

Biomark Res
Chen W, Yu J, Ge S, Yuan T, Ding X, Yan B, Ye L, Wang Y, Jia R.   +8 more
europepmc   +1 more source

Astrocyte Regulation of Spinal Circuit Function

Journal of Neurochemistry, Volume 170, Issue 2, February 2026.
Spinal cord astrocytes exist as an additional component of the computational framework that governs both sensory perceptions and motor outputs (left). By integrating local synaptic activity together with signals that reflect whole‐body state (e.g., neuromodulators, immune signals, and vascular signals) into defined input states (Sn), astrocytes adapt ...
Mary Kaye Duff, Min Jun Li, Axel Nimmerjahn   +2 more
wiley   +1 more source

Vasoactivity of Rac GTPase, Cytohesin and Kinase Inhibitors in Renal Interlobar and Coronary Arteries Reveals Shared and Distinct Patterns of Inhibitory Effects in Vascular and Prostate Smooth Muscle Contraction. [PDF]

Pharmacol Res Perspect
Liu G, Hu S, Tamalunas A, Kale O, Xu Y, Stief CG, Hennenberg M.   +6 more
europepmc   +1 more source

Grief‐Related Chest Pain: A Review, Conceptual Analysis, and Integrative Model

Psychophysiology, Volume 63, Issue 2, February 2026.
ABSTRACT Although the death of a loved one is a ubiquitous experience with chest pain a commonly reported symptom, grief‐related chest pain and particularly its physiological mechanisms remain under‐investigated. To address this gap, we adopted Rodger's approach to concept analysis to explore the psychoneuroimmunological mechanisms potentially linking ...
Sophia R. Evstigneev, Frank H. Wilhelm, George M. Slavich, David Blum, Annina Seiler   +4 more
wiley   +1 more source

Drug Repositioning in Doxorubicin-Induced Cardiotoxicity Protection. [PDF]

Int J Mol Sci
Kosić M, Pajović V, Jovanović M, Japundžić-Žigon N.   +3 more
europepmc   +1 more source

Effects of cAMP and CFTR modulation on apical fluid pH in human airway Calu‐3 cells

Physiological Reports, Volume 14, Issue 3, February 2026.
Abstract The airway epithelium serves as the first line of defense against inhaled insults present in the external environment by acting as a physical barrier and through host defense mechanisms. Proper maintenance of these host defense mechanisms relies on the regulation of airway surface liquid (ASL) composition and properties, a process that is ...
Jenny P. Nguyen, Nadia Milad, Jeremy A. Hirota   +2 more
wiley   +1 more source