Results 181 to 190 of about 28,675 (270)
Arrestins as Possible Drug Targets. [PDF]
Cinviz ZN +4 more
europepmc +1 more source
ABSTRACT Chronic kidney disease (CKD) is associated with inflammation and cardiovascular complications and is partly exacerbated by the uremic toxin indoxyl sulfate (IS). IS is known to activate the aryl hydrocarbon receptor (AhR) to promote vascular inflammation.
Hiroyuki Sasaki +8 more
wiley +1 more source
Neurotransmitters in tumors: chemical cross-talk shaping tumor progression. [PDF]
Chen W +8 more
europepmc +1 more source
The endocrine system coordinates whole body cellular function and maintains homeostasis. Alcohol impacts the integrity of endocrine regulation at multiple sites, contributing to risk for comorbidities. Some of the alcohol‐mediated pathophysiological effects on the endocrine system include alterations in receptor expression and responsiveness, protein ...
Patricia E. Molina, Liz Simon
wiley +1 more source
Vasoactivity of Rac GTPase, Cytohesin and Kinase Inhibitors in Renal Interlobar and Coronary Arteries Reveals Shared and Distinct Patterns of Inhibitory Effects in Vascular and Prostate Smooth Muscle Contraction. [PDF]
Liu G +6 more
europepmc +1 more source
Activation by G protein beta gamma subunits of beta-adrenergic and muscarinic receptor kinase.
Kimihiko Kameyama +5 more
openalex +1 more source
Drug Repositioning in Doxorubicin-Induced Cardiotoxicity Protection. [PDF]
Kosić M +3 more
europepmc +1 more source
Expanding the Immunologic and Neuronal Landscape of IgE‐Mediated Anaphylaxis
ABSTRACT Anaphylaxis is a life‐threatening immunoglobulin E (IgE)‐mediated type I hypersensitivity reaction with rising prevalence and burden. It involves mast cell degranulation upon cross‐linking of antigen on mast cell‐bound IgE. Mechanisms of IgE‐mediated anaphylaxis remain incompletely understood, particularly the induction of systemic symptoms ...
Ruchi Biswas +2 more
wiley +1 more source
Multi-region mapping of ligand binding and structural changes in the β-1 adrenergic receptor using carbene footprinting and mass spectrometry. [PDF]
Lloyd JR +7 more
europepmc +1 more source

