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Protein kinase activity of phosphoinositide 3-kinase regulates β-adrenergic receptor endocytosis
Nature Cell Biology, 2005Phosphoinositide 3-kinase (PI(3)K) is a unique enzyme characterized by both lipid and protein kinase activities. Here, we demonstrate a requirement for the protein kinase activity of PI(3)K in agonist-dependent beta-adrenergic receptor (betaAR) internalization.
Sathyamangla V, Naga Prasad +3 more
openaire +2 more sources
β-Adrenergic Receptor Kinase: Primary Structure Delineates a Multigene Family
Science, 1989The β-adrenergic receptor kinase (β-ARK), which specifically phosphorylates only the agonist-occupied form of the β-adrenergic and closely related receptors, appears to be important in mediating rapid agonist-specific (homologous) desensitization.
Benovic JL +4 more
openaire +2 more sources
Involvement of protein kinase in the regulation of beta-adrenergic receptors by antidepressants.
International journal of clinical pharmacology research, 1989The role of serotonin (5-HT) and protein kinases in the regulation of the beta-receptor induced by typical and atypical antidepressants was investigated. Treatment with either mianserin or maprotiline for seven days produced a significant decrease in the beta-receptor density measured 6h after the last dose.
M, Asakura +9 more
openaire +1 more source
Critical care management of chimeric antigen receptor T‐cell therapy recipients
Ca-A Cancer Journal for Clinicians, 2022Alexander Shimabukuro-Vornhagen +2 more
exaly
Current treatment and recent progress in gastric cancer
Ca-A Cancer Journal for Clinicians, 2021Smita S Joshi, Brian D Badgwell
exaly
A review of cancer immunotherapy toxicity
Ca-A Cancer Journal for Clinicians, 2020Lucy Boyce Kennedy
exaly