Results 201 to 210 of about 961,302 (242)
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Specific nonopiate receptors for beta-endorphin.
Science, 1979Iodinated beta H-[2-D-alanine]endorphin exhibits specific binding to cultured human lymphocytes. The binding is inhibited by low concentrations of beta-endorphin and its D-alanine derivative, but is not affected by opiate agonists and antagonists, or by ...
E. Hazum, K. Chang, P. Cuatrecasas
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Pharmacologic Studies of Beta-Endorphin in Psychopathology
Psychiatric Clinics of North America, 1983The pharmacologic trials of beta-endorphin in the field of mental illness are critically reviewed in this article, with an emphasis on the therapeutic efficacy of beta-endorphin in schizophrenia and affective disorders.
Philip A. Berger, Jack D. Barchas
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Beta-endorphin and the endocrine pancreas. Studies in healthy and diabetic human beings.
New England Journal of Medicine, 1983Beta-endorphin is present in the endocrine pancreas, suggesting that endorphins may have a role in islet-cell function. To evaluate this possibility, we infused synthetic human beta-endorphin intravenously in healthy volunteers and in insulin-dependent ...
M. Feldman, R. Kiser, R. H. Unger, C. Li
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Pancreatic Beta-Endorphin-Like Polypeptides
Pharmacology, 1981Acid extracts of porcine pancreas acetone powders (but not of other tissues) have been shown to contain material which will react firstly in a radioimmunoassay for beta-endorphin, and secondly, compete with 3H-Naloxone and 3H-enkephalinamide in the radio-receptor assay.
John C. Houck +2 more
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Science, 1979
Immunoreactive beta-endorphin was measured in the ventricular fluid of six patients with chronic pain. Stimulation of the periaqueductal gray matter in three patients with pain of peripheral origin resulted in significant increases (50 to 300 percent) in
Y. Hosobuchi +3 more
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Immunoreactive beta-endorphin was measured in the ventricular fluid of six patients with chronic pain. Stimulation of the periaqueductal gray matter in three patients with pain of peripheral origin resulted in significant increases (50 to 300 percent) in
Y. Hosobuchi +3 more
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Neuroendocrinology, 1990
The concentration of beta-endorphin-immunoreactivity (beta E-IR) in cerebrospinal fluid (CSF) and plasma of rats was determined following intracerebroventricular (ICV) treatment of conscious animals with substances known to stimulate the release of beta E and other pro-opiomelanocortin (POMC)-derived peptides at the level of the anterior and ...
C. G. P. Sweep +4 more
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The concentration of beta-endorphin-immunoreactivity (beta E-IR) in cerebrospinal fluid (CSF) and plasma of rats was determined following intracerebroventricular (ICV) treatment of conscious animals with substances known to stimulate the release of beta E and other pro-opiomelanocortin (POMC)-derived peptides at the level of the anterior and ...
C. G. P. Sweep +4 more
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Dexamethasone suppresses beta-endorphin in humans
Psychoneuroendocrinology, 1985Studies assessing the effect of glucocorticoids on beta-endorphin regulation in man have yielded inconsistent results. As measured by a highly specific beta-endorphin assay procedure, plasma immunoreactive beta-endorphin (irB-EP) in six healthy subjects was significantly suppressed, along with cortisol, after a 2 mg oral dose of dexamethasone (DEX ...
Walter A. Brown, David E. Krantz
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Plasma immunoreactive beta-endorphin in bulimics
Psychological Medicine, 1986SynopsisThe plasma beta-endorphin response to glucose ingestion was compared in 8 bulimics and 8 controls. The bulimics demonstrated a sustained elevation of plasma beta-endorphin unrelated to glucose ingestion throughout the 5-hour study period. It is hypothesized that such an elevation of beta-endorphin is the result of stress and that it may play an
Carl J. Getto +3 more
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Human EEG response to beta-endorphin
Psychiatry Research, 1979Beta-endorphin, morphine, and saline were given intravenously to a single schizophrenic subject on separate occasions in a double-blind design. EEG spectral analyses performed on data collected before and after drug injection demonstrated that beta-endorphin and morphine produced similar increases in alpha power within 5 to 15 minutes after injection ...
Bert S. Kopell +6 more
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$beta;-ENDORPHIN IN HUMAN CEREBROSPINAL FLUID
The Lancet, 1978beta-endorphin is a brain peptide with potent morphine-like activity structurally related to the anterior pituitary hormone beta-lipotrophin (beta-L.P.H.). We have developed a radioimmunoassay for human beta-endorphin in plasma and cerebrospinal fluid (C.S.F.).
Lorraine McLoughlin +6 more
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