Results 71 to 80 of about 22,830 (249)

Evaluation of Maternal and Fetal Stress Hormones During the Process of Birth

Gynecology Obstetrics & Reproductive Medicine, 2018
Objective: This study aims to determine whether mode of delivery is associated with the endocrine stress response in mother and newborn. Study Design: This prospective observational study was conducted with 86 women with a normal singleton pregnancy who
Burcu Kisa Karakaya, Ozlem Moraloglu, Rahime Bedir Findik, Necati Hancerliogullari, Hatice Celik, Tuba Candar, Halil İbrahim Yakut   +6 more
doaj   +1 more source

Laughing During Conversations, But Not in Response to Digital Media, Is Associated With Less Loneliness, Social Isolation, and Social Withdrawal: A Cross‐Sectional Study of German Adults in 2023

Health Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background and Aims Due to the limited knowledge in this study area, we aimed to investigate the association of frequency of laughter with loneliness, social isolation (perceived and objective social isolation), and social withdrawal.
André Hajek, Angelina R. Sutin, Nicola Veronese, Pinar Soysal, Louis Jacob, Martina Luchetti, Razak M. Gyasi, Karel Kostev, Supa Pengpid, Karl Peltzer, Antonio Terracciano, Hans‐Helmut König   +11 more
wiley   +1 more source

Cannabinoid CB2 receptor‐mediated analgesia: mechanism‐based insights and therapeutic potential

British Journal of Pharmacology, Volume 182, Issue 21, Page 5090-5118, November 2025.
Agonists of the cannabinoid 2 (CB2) receptor have shown promise for the treatment of pain in a variety of animal models. However, despite current preclinical evidence supporting the use of CB2 agonists for pain, successful translation of findings from preclinical models to human patients is lacking.
Kelsey G. Guenther, Andrea G. Hohmann
wiley   +1 more source

Beta-endorphin levels in both painful and painless diabetic peripheral neuropathy and its relations to pain characters and severity [PDF]

, 2017
Introduction. In the peripheral nervous system (PNS), beta-endorphins produce analgesia by binding to opioid receptors (particularly of the mu subtype) at both preand post-synaptic nerve terminals, primarily exerting their effect through presynaptic ...
Elbioumy, Azza A., Elkhamisy, Enas T., Elnahas, Mamdouh R., Khalel, Mayada S.   +3 more
core   +2 more sources

The Evolution of Functional Amyloids and Their Impact on Host–Microbe Interactions

Advanced Science, Volume 12, Issue 38, October 13, 2025.
This review describes functional amyloids and highlights the importance of structural repetition and molecular mimicry that distinguish the amyloid fold. The authors describe how amyloid can be the last universal common ancestor of protein folds. The authors also discuss how microbes utilize functional amyloids and how the structural characteristics of
Divya Kolli, Saroj K. Rout, Roland Riek, Matthew R. Chapman   +3 more
wiley   +1 more source

Increase in plasma beta endorphins precedes vasodepressor syncope. [PDF]

Heart, 1993
Endogenous opioids have a tonic inhibitory effect on sympathetic tone and have been implicated in the pathophysiology of vasodepressor syncope. Plasma beta endorphin concentrations increase after vasodepressor syncope induced by exercise or by fasting.To take frequent samples for plasma beta endorphin estimation during tilt testing, and to determine ...
H. E. MacIntyre, D. R. Wallbridge, Keith G. Oldroyd, Alan P. Rae, S M Cobbe, C. E. Gray, M. A. Denvir   +6 more
openaire   +6 more sources

The effect of naltrexone as a carboplatin chemotherapy-associated drug on the immune response, quality of life and survival of dogs with mammary carcinoma. [PDF]

PLoS ONE, 2018
The objective of this study was to evaluate the effect of low-dose naltrexone (LDN) as a carboplatin chemotherapy-associated drug in female dogs with mammary carcinoma in benign mixed tumors (MC-BMT) after mastectomy and to assess its association with ...
Marília Carneiro Machado, João Moreira da Costa-Neto, Ricardo Dias Portela, Mário Jorge Melhor Heine D'Assis, Olindo Assis Martins-Filho, Stella Maria Barrouin-Melo, Natalie Ferreira Borges, Fabiana Lessa Silva, Alessandra Estrela-Lima   +8 more
doaj   +1 more source

μ‐Opioid Receptor Dynamics in the Parameningeal Tissue During Migraine Attacks

Annals of Neurology, Volume 98, Issue 4, Page 777-787, October 2025.
Objective The possible impact of meningeal μ‐opioid receptor (μOR) binding in migraine remains unknown. This study investigated μOR availability in the cranial parameninges involved in migraine initiation via nociceptor activation. Methods We used positron emission tomography with [11C] carfentanil, and measured μOR availability in meninges and ...
Dajung J. Kim, Manyoel Lim, Thiago D. Nascimento, Frank Porreca, Robert A. Koeppe, Nouchine Hadjikhani, Alexandre F. DaSilva   +6 more
wiley   +1 more source

Placenta ingestion by rats enhances d- and k-opioid antinociception, but suppresses m-opioid antinociception [PDF]

, 2004
Ingestion of placenta or amniotic fluid produces a dramatic enhancement of centrally mediated opioid antinociception in the rat. The present experiments investigated the role of each opioid receptor type (m, d, k) in the antinociception-modulating ...
DiPirro, Jean M., Kristal, Dr. Mark B.
core  

Evaluation of the Hypothalamus‐Hypophysis‐Adrenal Axis in Male Rats Programmed by Gestational Protein Restriction

Cell Biochemistry and Function, Volume 43, Issue 10, October 2025.
ABSTRACT Diet manipulations during the gestation of animal models, in this case, the lipoprotein diet, mimic the alterations related to low birth weight, providing studies of the mechanisms involved in chronic disease development in later life. Our research group identified in adult male rats submitted to gestational protein restriction, increased ...
Vinicius Schiavinatto Mariano, José Antonio Rocha Gontijo, Patrícia Aline Boer   +2 more
wiley   +1 more source