Results 71 to 80 of about 979,687 (295)

Cannabinoid CB2 receptor‐mediated analgesia: mechanism‐based insights and therapeutic potential

open access: yesBritish Journal of Pharmacology, EarlyView.
Agonists of the cannabinoid 2 (CB2) receptor have shown promise for the treatment of pain in a variety of animal models. However, despite current preclinical evidence supporting the use of CB2 agonists for pain, successful translation of findings from preclinical models to human patients is lacking.
Kelsey G. Guenther, Andrea G. Hohmann
wiley   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

open access: yesBritish Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi   +10 more
wiley   +1 more source

The Relationship Between Course of Illness and β-Endorphin Plasma Levels in Patients with Schizophrenia

open access: yesNeuropsychiatric Disease and Treatment, 2020
Małgorzata Urban-Kowalczyk,1 Magdalena Kotlicka-Antczak,1 Dominik Strzelecki,1 Ewa Rudecka,2,3 Janusz Śmigielski4 1Department of Affective and Psychotic Disorders, Medical University of Łódź, Łódź, Poland; 2Babiński Memorial Hospital in Ł ...
Urban-Kowalczyk M   +4 more
doaj  

Effect of combined aerobic and resistance training on aerobic fitness, strength, beta-endorphin, blood glucose level, and insulin resistance in women with type II diabetes mellitus [PDF]

open access: yesMajallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2018
Introduction:Diabetes mellitus is one of the most common metabolic disorders and important public health problems. This disease accounts for 9% of all mortalities in the world and can lead to neuropathy, nephropathy, retinopathy, and cardiac disease in ...
Malihe Esmaeili   +2 more
doaj   +1 more source

Efficacy and welfare effects of different forms of physical restraint for upper airway endoscopy of horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Physical restraint of horses for veterinary procedures is necessary to allow completion of tasks effectively and without injury to patient or personnel. Objectives To compare physiological effects and behavioural responses to four commonly used restraint techniques for upper respiratory tract (URT) endoscopy in unsedated horses ...
Claire O'Brien   +5 more
wiley   +1 more source

Acupuncture for Chronic Pain Management in Haemophilic Arthropathy: A Systematic Review

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Haemophilia is a severe hereditary bleeding disorder affecting ∼1 in 5000 males, caused by deficiencies in coagulation factors VIII or IX. Chronic pain from haemophilic arthropathy (HA), especially in target joints, reduces quality of life (HRQOL), range of motion (ROM) and daily function.
Andrea Demeco   +4 more
wiley   +1 more source

Evaluation of Maternal and Fetal Stress Hormones During the Process of Birth

open access: yesGynecology Obstetrics & Reproductive Medicine, 2018
Objective: This study aims to determine whether mode of delivery is associated with the endocrine stress response in mother and newborn. Study Design: This prospective observational study was conducted with 86 women with a normal singleton pregnancy who
Burcu Kisa Karakaya   +6 more
doaj   +1 more source

Academic Achievement and Emotional Education Using Music Learning in Spain

open access: yesKyklos, EarlyView.
ABSTRACT In the current research work, we intend to analyse the effect of music on developing students' academic performance, self‐concept and emotional development. We work with experimental data gathered from an application of special music lessons at schools aimed at developing students' learning and at educating their emotions in the academic year ...
Oscar David Marcenaro‐Gutierrez   +2 more
wiley   +1 more source

µ1-Opioid Rezeptor vermittelte Effekte von Beta-Endorphin auf die endotheliale und monozytäre Endothelin-1 und Stickstoffmonooxid Freisetzung [PDF]

open access: yes, 2009
Neben den klassischen kardiovaskulären Risikofaktoren sind psychosoziale Faktoren wie chronischer Stress oder Depression in der Genese der Atherosklerose von Bedeutung.
Barth, Stefan
core  

Phosphodiesterase Type 5 Inhibitors, Sport and Doping [PDF]

open access: yes, 2017
Phosphodiesterase type 5 inhibitors (PDE5i) (e.g., sildenafil, tadalafil, vardenafil, and avanafil) are drugs commonly used to treat erectile dysfunction, pulmonary arterial hypertension, and benign prostatic hyperplasia.
Borrione, Paolo   +8 more
core   +1 more source

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