Results 71 to 80 of about 979,687 (295)
Cannabinoid CB2 receptor‐mediated analgesia: mechanism‐based insights and therapeutic potential
Agonists of the cannabinoid 2 (CB2) receptor have shown promise for the treatment of pain in a variety of animal models. However, despite current preclinical evidence supporting the use of CB2 agonists for pain, successful translation of findings from preclinical models to human patients is lacking.
Kelsey G. Guenther, Andrea G. Hohmann
wiley +1 more source
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi+10 more
wiley +1 more source
Małgorzata Urban-Kowalczyk,1 Magdalena Kotlicka-Antczak,1 Dominik Strzelecki,1 Ewa Rudecka,2,3 Janusz Śmigielski4 1Department of Affective and Psychotic Disorders, Medical University of Łódź, Łódź, Poland; 2Babiński Memorial Hospital in Ł ...
Urban-Kowalczyk M+4 more
doaj
Effect of combined aerobic and resistance training on aerobic fitness, strength, beta-endorphin, blood glucose level, and insulin resistance in women with type II diabetes mellitus [PDF]
Introduction:Diabetes mellitus is one of the most common metabolic disorders and important public health problems. This disease accounts for 9% of all mortalities in the world and can lead to neuropathy, nephropathy, retinopathy, and cardiac disease in ...
Malihe Esmaeili+2 more
doaj +1 more source
Abstract Background Physical restraint of horses for veterinary procedures is necessary to allow completion of tasks effectively and without injury to patient or personnel. Objectives To compare physiological effects and behavioural responses to four commonly used restraint techniques for upper respiratory tract (URT) endoscopy in unsedated horses ...
Claire O'Brien+5 more
wiley +1 more source
Acupuncture for Chronic Pain Management in Haemophilic Arthropathy: A Systematic Review
ABSTRACT Introduction Haemophilia is a severe hereditary bleeding disorder affecting ∼1 in 5000 males, caused by deficiencies in coagulation factors VIII or IX. Chronic pain from haemophilic arthropathy (HA), especially in target joints, reduces quality of life (HRQOL), range of motion (ROM) and daily function.
Andrea Demeco+4 more
wiley +1 more source
Evaluation of Maternal and Fetal Stress Hormones During the Process of Birth
Objective: This study aims to determine whether mode of delivery is associated with the endocrine stress response in mother and newborn. Study Design: This prospective observational study was conducted with 86 women with a normal singleton pregnancy who
Burcu Kisa Karakaya+6 more
doaj +1 more source
Academic Achievement and Emotional Education Using Music Learning in Spain
ABSTRACT In the current research work, we intend to analyse the effect of music on developing students' academic performance, self‐concept and emotional development. We work with experimental data gathered from an application of special music lessons at schools aimed at developing students' learning and at educating their emotions in the academic year ...
Oscar David Marcenaro‐Gutierrez+2 more
wiley +1 more source
µ1-Opioid Rezeptor vermittelte Effekte von Beta-Endorphin auf die endotheliale und monozytäre Endothelin-1 und Stickstoffmonooxid Freisetzung [PDF]
Neben den klassischen kardiovaskulären Risikofaktoren sind psychosoziale Faktoren wie chronischer Stress oder Depression in der Genese der Atherosklerose von Bedeutung.
Barth, Stefan
core
Phosphodiesterase Type 5 Inhibitors, Sport and Doping [PDF]
Phosphodiesterase type 5 inhibitors (PDE5i) (e.g., sildenafil, tadalafil, vardenafil, and avanafil) are drugs commonly used to treat erectile dysfunction, pulmonary arterial hypertension, and benign prostatic hyperplasia.
Borrione, Paolo+8 more
core +1 more source