Results 181 to 190 of about 1,020,842 (327)

Significance of the detection of beta-galactosidase and of beta-xylosidase in the taxonomic study of the genus Haemophilus.

, 1979
W Hansen, E. Schoutens, E. Yourassowsky
openalex   +1 more source

SIRT1 Prevents Lens Epithelial Cell Senescence During Age‐Related Cataract via Regulating p66Shc

Aging Cell, EarlyView.
Schematic illustration of NMN‐mediated alleviation of age‐related cataract via SIRT1/p66Shc pathway–dependent inhibition of mitochondrial dysfunction and LEC senescence. ABSTRACT Lens epithelial cell (LEC) senescence is one of the key pathological processes of age‐related cataract (ARC) and is associated with oxidative stress, mitochondrial dysfunction,
Huirui Liu, Liyao Sun, Yu Mi, Yi Gao, Jialin Luo, Fengchun Kang, Yujing Bai, Xiaohan Yu, Hongyan Ge   +8 more
wiley   +1 more source

Importância da pesquisa da Beta-galactosidase na caracterização laboratorial da Neisserialactamica

, 1978
Ilka Maria Landgraf Lee, Gil Vital Álvares Pessôa, Maria Regina Novaes Ramires Esper, Carmo Elias Andrade Melles, Vera Simonsen   +4 more
openalex   +2 more sources

BubR1 Insufficiency Drives Transcriptomic Alterations and Pathology Associated With Cardiac Aging and Heart Failure

Aging Cell, EarlyView.
Transcriptomic and cellular analyses of BubR1 hypomorphic hearts reveal disruptions in key pathways and upregulation of markers linked to impaired cardiac structure and function. Comparative transcriptomic analysis shows that BubR1 insufficiency mirrors changes seen in aged and failing hearts. A key finding of this study is that BubR1 levels decline in
Renju Pun, Aliya L. Haas, Aradhana Thapa, Sylar R. Takafuji, Rexton M. Suzuki, Gabrielle F. Kay, Li Zheng, Michelle Waknitz, Michael H. Kim, Darren J. Baker, Jan M. van Deursen, Paul L. Sorgen, Rebekah L. Gundry, Brian J. North   +13 more
wiley   +1 more source

STUDIES ON BETA-N-ACETYLHEXOSAMINIDASE AND BETA-GALACTOSIDASE FROM TURBO CORNUTUS

, 1978
KWOK-KAM YEUNG
openalex   +2 more sources

Enhanced expression of cro‐beta‐galactosidase fusion proteins under the control of the PR promoter of bacteriophage lambda.

EMBO Journal, 1982
M. Zabeau, K. Stanley
semanticscholar   +1 more source

Senescence Alters Antimicrobial Peptide Expression and Induces Amyloid‐β Production in Retinal Pigment Epithelial Cells

Aging Cell, EarlyView.
Healthy RPE cells produce AMPs and AMP precursors, including amyloid precursor protein (APP) and chemerin, and protect the neuroretina from blood‐borne pathogens and maintain homeostasis. When RPE cells undergo senescence, the antibacterial activity declines, and APP undergoes amylogenesis, leading to Aβ deposition.
Jian Liu, Caijiao Yi, Jinyan Qi, Xuexue Cui, Xiangling Yuan, Wen Deng, Mei Chen, Heping Xu   +7 more
wiley   +1 more source

Aging Adipose‐Derived Mesenchymal Stem Cells, Cultured on a Native Young Extracellular Matrix, Are Protected From Senescence and Apoptosis Along With Increased Expression of HLA‐DR and CD74 Associated With PI3K Signaling

Aging Cell, EarlyView.
The maintenance of aging mesenchymal stem cells (MSCs) on extracellular matrix synthesized by human amniotic fluid‐derived pluripotent stem cells (ECM Plus), a young microenvironment, remarkably restored their quantity and quality along with up‐regulating HLA‐DR and CD74.
Aaron O. Gonzalez, Parveez A. Abdul Azees, Jerry P. Chen, Milos Marinkovic, Brian Cao, Ting Liang, Peiqing Hu, Chih‐Ko Yeh, David D. Dean, Yidong Bai, Xiao‐Dong Chen   +10 more
wiley   +1 more source

Use of fluorescein-di-beta-D-galactopyranoside (FDG) and C12-FDG as substrates for beta-galactosidase detection by flow cytometry in animal, bacterial, and yeast cells [PDF]

, 1994
Antonia Plovins, Alberto Álvarez, Lourdes Ibáñez, Marı́a Molina, César Nombela   +4 more
openalex   +1 more source

L‐Tryptophan Produced by Bifidobacterium pseudocatenulatum NCU‐08 Delays Aging in SAMP8 Mice by Activating the Sirt1/P53/P21/Rb Signaling Pathway

Aging Cell, EarlyView.
Bifidobacterium pseudocatenulatum NCU‐08, isolated from the feces of centenarians, facilitated the entry of L‐tryptophan into hippocampal neurons of SAMP8 mice, where it was metabolized into NAD+. The increased NAD+ levels activated Sirt1 protein, thereby suppressing the expression of senescence‐associated proteins P53, P21, and Rb, ultimately delaying
Tangchang Xu, Xiaoyun Wu, Yifei Zhang, Yujie Cai, Xinfeng Zhang, Qingwei Zeng, Jie Luo, Jing Wei, Tingtao Chen   +8 more
wiley   +1 more source