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Cytotoxic and senescence-inducing effects of BLU554 in pancreatic ductal adenocarcinoma: an in vitro study. [PDF]
Fujiwara M +8 more
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Generalized Gangliosidosis: Beta-Galactosidase Deficiency
Science, 1968A profound deficiency (10- to 30-fold) of β-galactosidase activity was found in tissues (liver, spleen, kidney, and brain) from two patients with generalized gangliosidosis; this deficiency is demonstrated as a failure to cleave both p -nitrophenyl-β-D-galactopyranoside and ganglioside GM 1 ...
S, Okada, J S, O'Brien
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Beta-Galactosidase of Helix pomatia
Nature, 1964THE digestive juice of Helix pomatia contains a remarkable number of enzymes; many of them are carbohydrases, and they include an enzyme that hydrolyses lactose or β-methyl-galactoside1,2. This communication describes the properties and activities of the enzyme that hydrolyses o-nitrophenyl-β-D-galactopyranoside (ONPG).
R, GOT, A, MARNAY, P, JARRIGE, J, FONT
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Three cases of beta-galactosidase deficiency
Klinische Pädiatrie, 1981A clinical description of three cases of beta-galactosidase deficiency is presented. Two cases are classical for infant type GM1-gangliosidosis, the third is characterised by dysostosis multiplex with growth retardation and of normal intelligence. Laboratory data revealed mucopolysaccharides in the urine of all described patients in a high level of ...
E, Pronicka +3 more
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Beta-galactosidase from Aureobasidium pullulans
Letters in Applied Microbiology, 1989Aureobasidium pullulans is a new source of enzyme beta-galactosidase with optimum activity at pH 6·8 and a temperature of 45°C. Lactose induced enzyme synthesis, but low constitutive levels of enzyme were seen with other sugars. Addition of Mn2+ and Ca2+ increased enzyme production and activity. Co2+ was a strong activator of enzyme activity.
M.S. Deshpande +2 more
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Beta-Galactosidase Staining in the Skeleton
2014The lacZ gene, encoding for the β-galactosidase enzyme, is widely used as a reporter gene in bone biology due to the ease of visualization in situ on whole-mount or on tissue sections. In this protocol we provide detailed methods for visualizing this reporter gene for both in vivo and in vitro studies.
X L, Han, Jian Q, Feng
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