Results 231 to 240 of about 76,944 (297)

Targeting of Staphyloxanthin and α‐Hemolysin by Natural Compound L‐Malic Acid Suppresses Staphylococcus aureus Virulence

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
L‐malic acid, a natural TCA cycle intermediate, attenuates the virulence of Staphylococcus aureus through dual metabolic and regulatory mechanisms. It redirects central carbon flux away from the mevalonate pathway and inhibits the key enzyme CrtO, suppressing staphyloxanthin biosynthesis and impairing bacterial resistance to oxidative stress ...
Li Shen, Bingjie Wang, Jinjin Yang, Xinru Yuan, Zhixuan Chen, Can Yang, Jiana Fu, Haojin Gao, Weihua Han, Junhong Shi, Fangyou Yu, Jingyi Yu   +11 more
wiley   +1 more source

Sex-based antibody subclass maturation drives direct enzymatic inhibition in fabry disease patients receiving enzyme replacement therapy. [PDF]

Front Mol Biosci
Baldwin T, Kurdi H, Doykov I, Robertson F, Rosmini S, Nordin S, Augusto J, Kozor R, Baruteau J, Davison J, Moreno-Martinez D, Ramaswami U, Vijapurapu R, Geberhiwot T, Steeds R, Moon J, Hughes D, Mills K, Heywood WE.   +18 more
europepmc   +1 more source

N‐Glycosyl Triazoline Glycomimetics via Huisgen Cycloaddition With an Electron‐Deficient Alkene and BF3‐Catalysed Triazoline Fragmentation to Aziridines

European Journal of Organic Chemistry, Volume 29, Issue 22, 9 June 2026.
Glycomimetics with triazoline and aziridine groups were synthesised via diastereoselective Huisgen cycloaddition from glycosyl azides. Density functional theory was applied to define the mechanism for BF3 promoted aziridine formation. Triazoline and aziridine derivatives were synthesised by diastereo‐ and regioselective Huisgen cycloaddition of 2,3,4,6‐
Aaron McCormack, Ashis Dhara, Lamis Alaa Eldin Refat, Mikael Bols, Paul V. Murphy   +4 more
wiley   +1 more source

PPAR-γ agonist Inactivate Cellular Senescence by Inhibiting SIRT1 Signaling to Confer Increased Sensitivity to Olaparib in Ovarian Cancer Cells. [PDF]

Saudi J Med Med Sci
Wang Z, Miao W, Gao J, Zhang X.
europepmc   +1 more source

Optimized Whole-Mount X-gal Staining to Detect Hedgehog Signaling Activity in Basal Cell Carcinoma: A Platform for Spatial Integration with Immune Analysis. [PDF]

Methods Mol Biol
Wang H, Zhu Y, Kim AL.
europepmc   +1 more source

Iron and peroxide regulation of the PrrF sRNAs and a conserved ferritin family protein in <i>Pseudomonas aeruginosa</i> and <i>Pseudomonas fluorescens</i>. [PDF]

J Bacteriol
Ouattara KO, Chourashi R, Oglesby AG.
europepmc   +1 more source

The Influence of Short Peptides on Cell Senescence and Neuronal Differentiation. [PDF]

Curr Issues Mol Biol
Sakhenberg E, Linkova N, Kraskovskaya N, Krieger D, Polyakova V, Medvedev D, Krasichkov A, Khotin M, Ryzhak G.   +8 more
europepmc   +1 more source

Mycobacterium leprae small heat shock protein-18 complements Lon protease in Escherichia coli. [PDF]

BMC Microbiol
Rehna EA, Dharmalingam K, Natesan S.
europepmc   +1 more source