Results 1 to 10 of about 542,977 (297)
Pericentromeric repetitive ncRNA regulates chromatin interaction and inflammatory gene expression
Nucleus, 2022 Cellular senescence provokes a dramatic alteration of chromatin organization and gene expression profile of proinflammatory factors, thereby contributing to various age-related pathologies via the senescence-associated secretory phenotype (SASP ...
Kenichi Miyata, Akiko Takahashi
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Nature Communications, 2022 Ras mutations induce cell competition and cellular senescence to inhibit the proliferation of oncogenic mutated cells. Here the authors demonstrate that cellular senescence inhibits cell competition-induced elimination of oncogenic cells through HGF ...
Nanase Igarashi +12 more
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Telomere Maintenance and the cGAS-STING Pathway in Cancer
Cells, 2022 Cancer cells exhibit the unique characteristics of high proliferation and aberrant DNA damage response, which prevents cancer therapy from effectively eliminating them.
Hiroshi Ebata +2 more
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Communications Biology, 2022 Cellular senescence caused by oncogenic stimuli is associated with the development of various age-related pathologies through the senescence-associated secretory phenotype (SASP).
Sho Sugawara +20 more
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The Skin Epilipidome in Stress, Aging, and Inflammation
Frontiers in Endocrinology, 2021 Lipids are highly diverse biomolecules crucial for the formation and function of cellular membranes, for metabolism, and for cellular signaling. In the mammalian skin, lipids additionally serve for the formation of the epidermal barrier and as surface ...
Florian Gruber +10 more
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Developmental and age-related changes in apolipoprotein B mRNA editing in mice.
Journal of Lipid Research, 1992 Apolipoprotein B (apoB) mRNA is modified by a post-transcriptional editing reaction (C to U) changing a glutamine (CAA) to a translational stop codon (UAA) and producing apoB-48 mRNA in mammalian liver and intestine. Developmental and age-related changes
K Higuchi +3 more
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Acts of negotiation: toward a grounded theory of nursing practice in chronic wound care in Austria
BMC Health Services Research, 2023 Background Demographic change and the rise of diabetes mellitus are leading to a projected increase in the prevalence of chronic wounds. People suffering from chronic wounds experience significant losses in their health-related quality of life.
Deborah Drgac, Raffael Himmelsbach
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Redox Biology, 2021 The soluble receptor for advanced glycation end-products (sRAGE) has been classically considered a sink for pro-inflammatory RAGE ligands and as such has been associated with protection from inflammatory stress and disease.
Jorge D. Erusalimsky
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Myopathy with Concurrent Tadalafil and Simvastatin
Case Reports in Medicine, 2009 A 48-year-old man, using statin, was admitted to hospital with progressive myalgia after consumption of tadalafil and simvastatin. Muscle pain and penile erection disappeared seven days after interruption of therapy.
Maria Pia Gargante +3 more
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Hepatitis C Virus Infection Increases Fatigue in Health Care Workers
Diseases, 2020 Fatigue is a common state associated with a weakening or depletion of one’s physical and mental resources, that leads to the inability to continue the individual functioning at a normal level of activity.
Vito Emanuele Catania +8 more
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