Results 31 to 40 of about 492,919 (268)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa +8 more
wiley +1 more source
Regulation of leaf senescence in Arabidopsis : isolation and characterisation [PDF]
, 2005 The effect of ethylene exposure time on leaf senescence was studied in Arabidopsis accessions Ler-0, Col-0 and Ws-0 and in several old (onset of leaf death) mutants representing different genetic loci.
Jing, Hai-Chun,, Jing, Hai-Chun
core
Future atmospheric CO2 leads to delayed autumnal senescence
, 2007 Growing seasons are getting longer, a phenomenon partially explained by increasing global temperatures. Recent reports suggest that a strong correlation exists between warming and advances in spring phenology but that a weaker correlation is evident ...
BIRGIT GIELEN +34 more
core +1 more source
Aging, 2011 The discovery and analysis of microRNAs (miRNAs) has revealed a new mechanism of gene regulation. miRNAs can base-pair with specific mRNA targets and regulate their expression at the post-transcriptional level [1]. Changes in miRNA abundance are implicated in controlling many biological processes including cellular senescence [2], an irreversible form ...
Ivan, Martinez +2 more
openaire +2 more sources
Current Biology, 2022 Cellular senescence defines a state of stable and generally irreversible proliferative arrest associated with various morphological, structural and functional changes (Figure 1), including enhanced expression and secretion of pro-inflammatory and tissue-remodelling mediators.
Varela-Eirín, Marta, Demaria, Marco
openaire +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro +11 more
wiley +1 more source
Investigating the modulation of long non-coding RNAs associated to senescence using computational and biological approaches [PDF]
, 2022 Senescent cells (SC) are characterized by a distinct change in their morphology and gain of a senescence-associated secretory phenotype (SASP). A complex grid of molecular processes is implicated in the onset of the senescence that is in common also with
Sabrina Briguglio +9 more
core
Senescence vs. sustenance: Evolutionary-demographic models of aging [PDF]
Humans, and many other species, suffer senescence: mortality increases and fertility declines with adult age. Some species, however, enjoy sustenance: mortality and fertility remain constant.
James W. Vaupel, Annette Baudisch
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm +11 more
wiley +1 more source
Cellular senescence: a hitchhiker's guide.
, 2015 Since its first description over 50 years ago, cellular senescence has gained increasing attention. The number of research publications on cellular senescence last year alone is more than the number of publications in the decade in 1990s.
Aravinthan, Aloysious
core +1 more source