Results 11 to 20 of about 542,977 (297)
Hormonal changes during salinity-induced leaf senescence in tomato (Solanum lycopersicum L.) [PDF]
, 2008 Leaf senescence is one of the most limiting factors to plant productivity under salinity. Both the accumulation of specific toxic ions (e.g. Na+) and changes in leaf hormone relations are involved in the regulation of this process. Tomato plants (Solanum
Pérez-Alfocea, Francisco +7 more
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A senescent cell bystander effect: senescence‐induced senescence [PDF]
Aging Cell, 2012 SummarySenescent cells produce and secrete various bioactive molecules including interleukins, growth factors, matrix‐degrading enzymes and reactive oxygen species (ROS). Thus, it has been proposed that senescent cells can damage their local environment, and a stimulatory effect on tumour cell growth and invasiveness has been documented.
Nelson G +6 more
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SENESCENCE AND SENILITY. [PDF]
The Lancet, 1922 n ...
Thompson, R. J. C., Todd, R. E.
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Senescence is not inevitable [PDF]
Biogerontology, 2017 Senescence, the physiological deterioration resulting in an increase in mortality and decline in fertility with age, is widespread in the animal kingdom and has often been regarded as an inescapable feature of all organisms. This essay briefly describes the history of the evolutionary theoretical ideas on senescence. The canonical evolutionary theories
Owen R. Jones, James W. Vaupel
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A mechanistic investigation into candidate markers of telomere-induced senescence in normal human epidermal keratinocytes [PDF]
, 2014 PhDTelomere dysfunction is one mechanism of cellular and tissue ageing. Dysfunctional telomeres in fibroblasts are recognised as DNA double-strand breaks (DSBs) and trigger the DNA damage pathway of senescence.
dos Santos Soares Martins de Castro, Alicia Maria
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Current Biology, 2022 Cellular senescence defines a state of stable and generally irreversible proliferative arrest associated with various morphological, structural and functional changes (Figure 1), including enhanced expression and secretion of pro-inflammatory and tissue-remodelling mediators.
Varela-Eirín, Marta, Demaria, Marco
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, 2016 Activation of oncogenic signaling paradoxically results in the permanent withdrawal from cell cycle and induction of senescence (oncogene-induced senescence (OIS)). OIS is a fail-safe mechanism used by the cells to prevent uncontrolled tumor growth, and, as such, it is considered as the first barrier against cancer.
Anna, Bianchi-Smiraglia +2 more
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Density dependence triggers runaway selection of reduced senescence [PDF]
, 2007 In the presence of exogenous mortality risks, future reproduction by an individual is worth less than present reproduction to its fitness. Senescent aging thus results inevitably from transferring net fertility into younger ages.
Doncaster, C. Patrick +7 more
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Oncotarget, 2015 Senescence is a state of stable cell growth arrest that can be triggered by multiple stressors, including oncogene activation [1]. In normal diploid mammalian cells, activation of oncogenes such as oncogenic RAS or BRAF decreases dNTP levels, which leads to replication stress and ultimately senescence [2].
Katherine M, Aird, Rugang, Zhang
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The transcriptome of Populus in elevated CO2 reveals increased anthocyanin biosynthesis during delayed autumnal senescence [PDF]
, 2010 The delay in autumnal senescence that has occurred in recent decades has been linked to rising temperatures. Here, we suggest that increasing atmospheric CO2 may partly account for delayed autumnal senescence and for the first time, through transcriptome
Tallis, M.J. +26 more
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