Results 21 to 30 of about 542,977 (297)

High levels of soluble RAGE are associated with a greater risk of mortality in COVID-19 patients treated with dexamethasone

open access: yesRespiratory Research, 2022
Blood levels of the soluble receptor for advanced glycation end-products (sRAGE) are acutely elevated during the host inflammatory response to infection and predict mortality in COVID-19.
Lee Butcher   +9 more
doaj   +1 more source

A specific group of genes respond to cold dehydration stress in cut Alstroemeria flowers whereas ambient dehydration stress accelerates developmental senescence expression patterns [PDF]

open access: yes, 2010
Petal development and senescence entails a normally irreversible process. It starts with petal expansion and pigment production, and ends with nutrient remobilization and ultimately cell death.
Rogers, H.   +28 more
core   +1 more source

Crosstalk between p53 modifiers at PML bodies

open access: yesMolecular & Cellular Oncology, 2018
Tumor protein p53 (TP53, best known as p53), the most frequently mutated tumor suppressor in cancer, plays a central role in cell fate decisions induced by DNA damage.
Sonja Matt, Thomas G Hofmann
doaj   +1 more source

Evaluación de formas cortas de extrasístoles auriculares recurrentes mediante ecocardiografía con deformación auricular izquierda en pacientes ambulatorios sin cardiopatía orgánica

open access: yesArchivos de Cardiología de México, 2023
Objetivo: Analizar la utilidad y relevancia clínica de la evaluación mediante ecocardiografía basada en las curvas de deformación auricular miocárdica con imágenes vectoriales de velocidad (VVI) de speckle-tracking, en el análisis de las extrasístoles ...
José M. Soler   +5 more
doaj   +1 more source

Genome wide CRISPR/Cas9 screen identifies the coagulation factor IX (F9) as a regulator of senescence

open access: yesCell Death and Disease, 2022
During this last decade, the development of prosenescence therapies has become an attractive strategy as cellular senescence acts as a barrier against tumour progression.
Paula Carpintero-Fernández   +10 more
doaj   +1 more source

Molecular Mechanisms of Alveolar Epithelial Stem Cell Senescence and Senescence-Associated Differentiation Disorders in Pulmonary Fibrosis

open access: yesCells, 2022
Pulmonary senescence is accelerated by unresolved DNA damage response, underpinning susceptibility to pulmonary fibrosis. Recently it was reported that the SARS-Cov-2 viral infection induces acute pulmonary epithelial senescence followed by fibrosis ...
Xiaojing Hong   +4 more
doaj   +1 more source

microRNA in cellular senescence [PDF]

open access: yes, 2010
Senescence is recognized as a permanent arrest of cell proliferation triggered by telomere shortening or various stresses. Senescence imposes a barrier to tumorigenesis and contributes to aging.
Sedia, Carla
core   +1 more source

Wheat leaf senescence and its regulatory gene network

open access: yesCrop Journal, 2021
Wheat leaf senescence is a developmental process that involves expressional changes in thousands of genes that ultimately impact grain protein content (GPC), grain yield (GY), and nitrogen use efficiency.
Nigarin Sultana   +3 more
doaj   +1 more source

Cellular Senescence

open access: yesAnnals of Medicine, 1992
The ageing of cells, cellular senescence, is an event that is encountered in all normal cells. Cells grown in vitro have a limited life span and do not grow well after a certain number of divisions. They cease to divide and eventually die. In accordance with this, the life expectancy of an established cell culture depends on the age of the donor. Cells
K, Koli, J, Keski-Oja
openaire   +2 more sources

Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney diseaseResearch in context

open access: yesEBioMedicine, 2019
Background: Senescent cells, which can release factors that cause inflammation and dysfunction, the senescence-associated secretory phenotype (SASP), accumulate with ageing and at etiological sites in multiple chronic diseases.
LaTonya J. Hickson   +32 more
doaj   +1 more source

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