Results 21 to 30 of about 675,022 (305)

Hepatitis C Virus Infection Increases Fatigue in Health Care Workers

Diseases, 2020
Fatigue is a common state associated with a weakening or depletion of one’s physical and mental resources, that leads to the inability to continue the individual functioning at a normal level of activity.
Vito Emanuele Catania, Giulia Malaguarnera, Giorgia Fiorenza, Eleonora Margherita Chisari, Anna Rita Lipari, Valentino Gallina, Manuela Pennisi, Giuseppe Lanza, Michele Malaguarnera   +8 more
doaj   +1 more source

High levels of soluble RAGE are associated with a greater risk of mortality in COVID-19 patients treated with dexamethasone

Respiratory Research, 2022
Blood levels of the soluble receptor for advanced glycation end-products (sRAGE) are acutely elevated during the host inflammatory response to infection and predict mortality in COVID-19.
Lee Butcher, Jun-Cezar Zaldua, Jose A. Carnicero, Karl Hawkins, Janet Whitley, Rangaswamy Mothukuri, Phillip A. Evans, Keith Morris, Suresh Pillai, Jorge D. Erusalimsky   +9 more
doaj   +1 more source

Evaluación de formas cortas de extrasístoles auriculares recurrentes mediante ecocardiografía con deformación auricular izquierda en pacientes ambulatorios sin cardiopatía orgánica

Archivos de Cardiología de México, 2023
Objetivo: Analizar la utilidad y relevancia clínica de la evaluación mediante ecocardiografía basada en las curvas de deformación auricular miocárdica con imágenes vectoriales de velocidad (VVI) de speckle-tracking, en el análisis de las extrasístoles ...
José M. Soler, Gemma García-Parés, Oliver Valero, Antonio Berruezo, Victor J. Yuste, María Antonia Baltrons   +5 more
doaj   +1 more source

High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation [PDF]

, 2011
Leaf senescence is an essential developmental process that impacts dramatically on crop yields and involves altered regulation of thousands of genes and many metabolic and signaling pathways, resulting in major changes in the leaf.
Beynon, Jim, Breeze, Emily, Buchanan-Wollaston, Vicky, Denby, Katherine J., Harrison, Elizabeth, Hickman, Richard J., Hill, Claire, Hughes, Linda Karen, Jackson, Stephen D., Jenkins, Dafyd J., Jenner, Carol E., Kiddle, Steven J., Kim, Youn-sung, Legaie, Roxane, McHattie, Stuart, Mead, A., Moore, Jonathan D., Morris, Karl, Ott, Sascha, Penfold, Christopher A., Rand, D. A., Tabrett, Alex, Thomas, Brian, Wild, David L., Zhang, Cunjin   +24 more
core   +2 more sources

Molecular Mechanisms of Alveolar Epithelial Stem Cell Senescence and Senescence-Associated Differentiation Disorders in Pulmonary Fibrosis

Cells, 2022
Pulmonary senescence is accelerated by unresolved DNA damage response, underpinning susceptibility to pulmonary fibrosis. Recently it was reported that the SARS-Cov-2 viral infection induces acute pulmonary epithelial senescence followed by fibrosis ...
Xiaojing Hong, Lihui Wang, Kexiong Zhang, Jun Liu, Jun-Ping Liu   +4 more
doaj   +1 more source

Cellular senescence and aging: the role of B-MYB [PDF]

, 2014
Cellular senescence is a stable cell cycle arrest, caused by insults, such as: telomere erosion, oncogene activation, irradiation, DNA damage, oxidative stress, and viral infection.
Jat, PS, Lam, EW, Mowla, SN
core   +1 more source

Crosstalk between p53 modifiers at PML bodies

Molecular & Cellular Oncology, 2018
Tumor protein p53 (TP53, best known as p53), the most frequently mutated tumor suppressor in cancer, plays a central role in cell fate decisions induced by DNA damage.
Sonja Matt, Thomas G Hofmann
doaj   +1 more source

Genome wide CRISPR/Cas9 screen identifies the coagulation factor IX (F9) as a regulator of senescence

Cell Death and Disease, 2022
During this last decade, the development of prosenescence therapies has become an attractive strategy as cellular senescence acts as a barrier against tumour progression.
Paula Carpintero-Fernández, Michela Borghesan, Olga Eleftheriadou, Belen Pan-Castillo, Juan Antonio Fafián-Labora, Tom P. Mitchell, Alejandro Yuste, Muge Ogrunc, Thomas D. Nightingale, Maria Mayan, Ana O’Loghlen   +10 more
doaj   +1 more source

A benign juvenile environment reduces the strength of antagonistic pleiotropy and genetic variation in the rate of senescence [PDF]

, 2015
The environment can play an important role in the evolution of senescence because the optimal allocation between somatic maintenance and reproduction depends on external factors influencing life expectancy.
Gonzalez G., Medawar P.B., Pigliucci M., Schlichting C.D.   +3 more
core   +2 more sources

Wheat leaf senescence and its regulatory gene network

Crop Journal, 2021
Wheat leaf senescence is a developmental process that involves expressional changes in thousands of genes that ultimately impact grain protein content (GPC), grain yield (GY), and nitrogen use efficiency.
Nigarin Sultana, Shahidul Islam, Angela Juhasz, Wujun Ma   +3 more
doaj   +1 more source