Results 141 to 150 of about 43,491 (333)

Risk of acute pancreatitis with DPP‐4 inhibitors versus SGLT2 inhibitors in medication‐naïve individuals with diabetes: A target trial emulation

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims We investigated whether dipeptidyl peptidase‐4 inhibitor (DPP‐4i) use was associated with a higher risk of acute pancreatitis compared with sodium–glucose cotransporter 2 inhibitor (SGLT2i) use in antidiabetic medication‐naïve individuals.
Takashi Tatewaki, Akira Okada, Yuya Kimura, Hideo Yasunaga   +3 more
wiley   +1 more source

A novel GH3-β-glucosidase from soda lake metagenomic libraries with desirable properties for biomass degradation

Scientific Reports
Beta-glucosidases catalyze the hydrolysis of the glycosidic bonds of cellobiose, producing glucose, which is a rate-limiting step in cellulose biomass degradation.
Oliyad Jeilu, Erik Alexandersson, Eva Johansson, Addis Simachew, Amare Gessesse   +4 more
doaj   +1 more source

Moderate Phosphorus Addition to Field-Grown Bananas Enhanced Soil Microbial Enzyme Activities but Had Negligible Impacts on Bacterial, Fungal, and Nematode Diversity

Applied Microbiology
On commercial banana (Musa spp.) plantations, soils are often supplemented with phosphorus (P) fertiliser to optimise production. Such additions may influence the diversity and function of soil microbial communities, which play important roles in P ...
Anna-Belle C. Clarke, Hazel R. Lapis-Gaza, Stuart Irvine-Brown, Rebecca Lyons, Jiarui Sun, Anthony B. Pattison, Paul G. Dennis   +6 more
doaj   +1 more source

A macrophage receptor for liver lysosomal .BETA.-glucosidase.

Cell Structure and Function, 1988
beta-Glucosidase was purified from lysosomal membranes isolated from rat liver. Binding and uptake of the purified beta-glucosidase were mediated via an apparently single binding site on rat peritoneal macrophages. The number of sites and the Kd were 4.20 X 10(4)/cell and 1.00 X 10(-7) M, respectively.
openaire   +3 more sources

SGLT2 inhibitors and mortality in older adults with diabetic kidney disease: A target trial emulation study

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Randomized controlled trials on sodium‐glucose cotransporter 2 (SGLT2) inhibitors have yielded inconsistent findings regarding mortality benefits. It remains unclear whether, and in which subgroups, SGLT2 inhibitors confer survival benefits in older adults with diabetic kidney disease (DKD).
Tatsuhiko Azegami, Hidehiro Kaneko, Akira Okada, Yuta Suzuki, Toshiyuki Ko, Kazuki Aoyama, Takashin Nakayama, Yuya Kimura, Katsuhiko Fujiu, Norifumi Takeda, Hiroyuki Morita, Takashi Yokoo, Koichi Node, Masaomi Nangaku, Norihiko Takeda, Hideo Yasunaga, Kaori Hayashi   +16 more
wiley   +1 more source

Navigating PRKCSH’s impact on cancer: from N-linked glycosylation to death pathway and anti-tumor immunity

Frontiers in Oncology
PRKCSH, also known as Glucosidase II beta subunit (GluIIβ), is a crucial component of the endoplasmic reticulum (ER) quality control system for N-linked glycosylation, essential for identifying and eliminating misfolded proteins.
Ratchada Cressey, Ratchada Cressey, Moe Thi Thi Han, Worapong Khaodee, Guo Xiyuan, Guo Xiyuan, Yuan Qing   +6 more
doaj   +1 more source

Biomodification of dentin collagen with hydroalcoholic propolis extract: Impact on resin–dentin adhesion

European Journal of Oral Sciences, EarlyView.
Abstract This in vitro study evaluated the effect of hydroalcoholic propolis extract (HPE) as a collagen cross‐linking agent for preserving the dentin–adhesive interface. Dentin beams from human third molars were demineralized with 10% phosphoric acid and assigned to five treatments: distilled water (control), 6.5% grape seed extract (GSE), and HPE at ...
Zidane Hurtado Rabelo, Edinaldo Gomes de Meneses Neto, Israel Simon Andrade Costa, Juliano Sartori Mendonça, Vanara Florêncio Passos, Sérgio Lima Santiago   +5 more
wiley   +1 more source

Antidiabetic Activities of Agarwood (Aquilaria malaccensis) Leaf Extracts via Enhanced Insulin Secretion in BRIN-BD11 Pancreatic Beta-Cells

Jurnal Sylva Lestari
Agarwood leaves (Aquilaria malaccensis), a non-timber forest products, shows significant potential as a source of antidiabetic compounds. This study aims to evaluate the antidiabetic activity of agarwood leaves and their cytotoxicity on pancreatic beta ...
Yanico Hadi Prayogo, Rita Kartika Sari, Zikri Hamidi, Wasrin Syafii, Eva Harlina, Bayu Febram Prasetyo   +5 more
doaj   +1 more source

Reinventing henna: Enzyme‐catalysed colour release from stabilized Lawsonia inermis L. extracts

International Journal of Cosmetic Science, EarlyView.
The instability and reduced dyeing performance of a cosmetic formulation containing 2‐hydroxy‐1,4‐naphthoquinone (lawsone), derived from Lawsonia inermis L., is demonstrated in comparison to a novel two‐component system. This system comprises one formulation with naturally occurring lawsone precursors and a second containing a specific hydrolase ...
Nele Dallmann, Volkmar Vill, Fabian Straske   +2 more
wiley   +1 more source

Truncated mutants of beta-glucosidase 2 (GBA2) are localized in the mitochondrial matrix and cause mitochondrial fragmentation. [PDF]

PLoS One, 2020
Sultana S, Stewart J, van der Spoel AC.
europepmc   +1 more source