Results 251 to 260 of about 43,491 (333)
ABSTRACT Clostridioides difficile infection presents an escalating clinical challenge due to the proliferation of hypervirulent and antibiotic‐resistant strains. The primary symptoms of disease, namely colitis and diarrhea, are induced by the release of two toxins: TcdA and TcdB.
Carly M. Catella +10 more
wiley +1 more source
Identification of new microbial enzymes from forest and marine ecosystems by functional metagenomics [PDF]
Barbeyron, Tristan +4 more
core
ABSTRACT The current study is aimed to reveal the phytoprofile of Selaginella inaequalifolia (Hook. & Grev.) Spring using GC–MS and predict the drug properties, toxicity, biological properties of S. inaequalifolia ethanolic extracts (SiEE) using in silico methods and in vitro toxicity assays, namely, MTT and BSLB assay.
Johnson Marimuthu Alias Antonysamy +4 more
wiley +1 more source
Therapeutic Potential of <i>Acalypha wilkesiana</i> in Type 2 Diabetes: A Review. [PDF]
Inshutiyimana S +5 more
europepmc +1 more source
ABSTRACT Balanites aegyptiaca (BA) is a plant of paramount potential for the management of diabetes mellitus. The study investigates in silico studies of natural library compounds including that from BA with the assistance of network pharmacology. Balanitesin (compound 1) exhibited the highest docking score and binding free energy (∆G) values of −14 ...
Surendra Kumar Gautam +8 more
wiley +1 more source
Computational-experimental integration identifies potent carbohydrate-hydrolyzing enzyme inhibitors from Nardostachys jatamansi: molecular docking, dynamics and pharmacokinetic predictions. [PDF]
Iqbal MJ +4 more
europepmc +1 more source
ABSTRACT Autosomal dominant polycystic kidney disease (ADPKD) and autosomal dominant polycystic liver disease (ADPLD) are inherited cystic conditions with overlapping features but distinct genetic causes and clinical courses. Here, we report a case of a 50‐year‐old woman with a clinical diagnosis of ADPKD, hypertension, preserved kidney function ...
Anna Katya Brossart +4 more
wiley +1 more source
Anti-diabetic effects of Dachaihu decoction combined with <i>Sanghuangporus vaninii</i>: insights from network pharmacology, intestinal flora, and liver metabolomics. [PDF]
Huang J +6 more
europepmc +1 more source

