Results 251 to 260 of about 43,491 (333)

Development of Peptide Glucosyltransferase Inhibitors With Comprehensive Coverage Across Clostridioides difficile Toxin B Sub‐Types

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 2, Page 310-323, February 2026.
ABSTRACT Clostridioides difficile infection presents an escalating clinical challenge due to the proliferation of hypervirulent and antibiotic‐resistant strains. The primary symptoms of disease, namely colitis and diarrhea, are induced by the release of two toxins: TcdA and TcdB.
Carly M. Catella   +10 more
wiley   +1 more source

Identification of new microbial enzymes from forest and marine ecosystems by functional metagenomics [PDF]

open access: yes, 2012
Barbeyron, Tristan   +4 more
core  

Chemical Profiling, In Silico and In Vitro Studies to Identify Potential CDK2 and mTOR Inhibitor From Selaginella inaequalifolia (Hook. & Grev.) Spring Ethanolic Extracts

open access: yesChemistry &Biodiversity, Volume 23, Issue 2, February 2026.
ABSTRACT The current study is aimed to reveal the phytoprofile of Selaginella inaequalifolia (Hook. & Grev.) Spring using GC–MS and predict the drug properties, toxicity, biological properties of S. inaequalifolia ethanolic extracts (SiEE) using in silico methods and in vitro toxicity assays, namely, MTT and BSLB assay.
Johnson Marimuthu Alias Antonysamy   +4 more
wiley   +1 more source

Therapeutic Potential of <i>Acalypha wilkesiana</i> in Type 2 Diabetes: A Review. [PDF]

open access: yesJ Diabetes Res
Inshutiyimana S   +5 more
europepmc   +1 more source

Computational Analysis of Balanites aegyptiaca Phytochemicals as Inhibitors of Human Pancreatic α‐Amylase

open access: yesChemistry &Biodiversity, Volume 23, Issue 2, February 2026.
ABSTRACT Balanites aegyptiaca (BA) is a plant of paramount potential for the management of diabetes mellitus. The study investigates in silico studies of natural library compounds including that from BA with the assistance of network pharmacology. Balanitesin (compound 1) exhibited the highest docking score and binding free energy (∆G) values of −14 ...
Surendra Kumar Gautam   +8 more
wiley   +1 more source

Dual Monogenic Cystic Disease Case Report: Autosomal Dominant Polycystic Kidney Disease and Autosomal Dominant Polycystic Liver Disease

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Autosomal dominant polycystic kidney disease (ADPKD) and autosomal dominant polycystic liver disease (ADPLD) are inherited cystic conditions with overlapping features but distinct genetic causes and clinical courses. Here, we report a case of a 50‐year‐old woman with a clinical diagnosis of ADPKD, hypertension, preserved kidney function ...
Anna Katya Brossart   +4 more
wiley   +1 more source

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