Results 21 to 30 of about 577 (171)

An open-label, acute clinical trial in adults to assess ketone levels, gastrointestinal tolerability, and sleepiness following consumption of (R)-1,3-butanediol (Avela™)

Frontiers in Physiology, 2023
Introduction: A study was undertaken to determine the acute effects of a beverage made with Avela™ (R)-1,3-butanediol, on blood beta-hydroxybutyrate (BHB) levels (using the Keto-Mojo monitor), gastrointestinal (GI) tolerability (using the modified visual
James Lowder, Shafagh Fallah, Carolina Venditti, Kathy Musa-Veloso, Vassili Kotlov   +4 more
doaj   +1 more source

Effects of energy and protein status on reproductive parameters and presence of subclinical ketosis in Brown Swiss cows postpartum [PDF]

SPERMOVA, 2021
This study aimed to determine protein and energy metabolites in postpartum Brown Swiss cows and their effect on the presence of subclinical ketosis and reproductive parameters.
Ide Unchupaico Payano, Edith Ancco Gomez, Eduardo Fernández Curi, Williams Olivera Acuña, Carlos Quispe Eulogio   +4 more
doaj   +1 more source

Chemical Proteomics Identifies Ketogenesis‐Mediated Cysteine Modifications Regulating Redox Function

Angewandte Chemie, EarlyView.
Herein, we report ketone body induce cysteine modifications beyond lysine acylation, as revealed by integrating chemical proteomics with open‐search methods. Among the modifications, cysteine crotonation (Ccr) was chemically validated by endogenous peptide‐based co‐elution assays.
Yuan‐Fei Zhou, Ling Zhang, Zhuoyi L. Niu, Xin Wang, Alejandro Storper, Ryan Hunt, Yingming Zhao, Nima Sharifi, Zhipeng A. Wang   +8 more
wiley   +2 more sources

Weight loss is proportional to increases in fasting serum beta-hydroxybutyrate concentrations in adults with severe obesity undergoing a meal replacement programme

Human Nutrition & Metabolism, 2023
Background: A better understanding of the influence of restricted dietary intake on circulating ketone concentrations might help to explain heterogeneity in the amount of weight lost in dietary interventions.
Francis Martin Finucane, Mohammed Faraz Rafey, Martin Leahy, Paula O'Shea, Tim O'Brien, Martin O'Donnell   +5 more
doaj   +1 more source

Production of poly-(beta-hydroxybutyric-co-beta-hydroxyvaleric) acids [PDF]

Applied and Environmental Microbiology, 1990
Alcaligenes latus, Alcaligenes eutrophus, Bacillus cereus, Pseudomonas pseudoflava, Pseudomonas cepacia, and Micrococcus halodenitrificans were found to accumulate poly-(beta-hydroxybutyric-co-beta-hydroxyvaleric) acid [P(HB-co-HV)] copolymer when supplied with glucose (or sucrose in the case of A.
B A, Ramsay, K, Lomaliza, C, Chavarie, B, Dubé, P, Bataille, J A, Ramsay   +5 more
openaire   +2 more sources

Contribution of 3-hydroxyisobutyrate to the measurement of 3-hydroxybutyrate in human plasma: comparison of enzymatic and gas-liquid chromatography-mass spectrometry assays in normal and in diabetic subjects.

Journal of Lipid Research, 1989
In this study we employed a capillary gas-liquid chromatographic-mass spectrometric (GLC-MS) method to measure the plasma concentrations of 3-hydroxybutyrate (3-OHB) and 3-hydroxyisobutyrate (3-OHIB) in overnight fasted diabetic subjects and in normal ...
A Avogaro, D M Bier
doaj   +1 more source

Mass spectrometry of the white adipose metabolome in a hibernating mammal reveals seasonal changes in alternate fuels and carnitine derivatives

Frontiers in Physiology, 2023
Mammalian hibernators undergo substantial changes in metabolic function throughout the seasonal hibernation cycle. We report here the polar metabolomic profile of white adipose tissue isolated from active and hibernating thirteen-lined ground squirrels ...
Frazer I. Heinis, Sophie Alvarez, Matthew T. Andrews   +2 more
doaj   +1 more source

D-beta-hydroxybutyrate extends lifespan in C. elegans

Aging, 2014
The ketone body beta-hydroxybutyrate (βHB) is a histone deacetylase (HDAC) inhibitor and has been shown to be protective in many disease models, but its effects on aging are not well studied. Therefore we determined the effect of βHB supplementation on the lifespan ofC. elegans nematodes. βHB supplementation extended mean lifespan by approximately 20%.
Edwards, Clare, Canfield, John, Copes, Neil, Rehan, Muhammad, Lipps, David, Bradshaw, Patrick C.   +5 more
openaire   +3 more sources

Beta‐hydroxybutyrate Concentrations in Dogs with Acute Pancreatitis and Without Diabetes Mellitus

Journal of Veterinary Internal Medicine, 2016
Background β‐hydroxybutyrate (BOHB) concentrations have not been quantified in dogs with acute pancreatitis (AP). Objective The aim of this study was to investigate BOHB concentrations in dogs with AP. Animals A total of 154 client‐owned dogs without DM.
F.E. Hurrell, K.J. Drobatz, R.S. Hess
doaj   +1 more source

Use of a glycogenic precursor during the prepartum period and its effects upon metabolic indicators and reproductive parameters in dairy cows

Revista Mexicana de Ciencias Pecuarias, 2020
The aim was to evaluate if 1-2 propanodiol plus calcium propionate (glycogenic precursor) supplementation during the transition period in high yielding dairy cows reduces metabolic and reproductive dysfunctions during early lactation.
Carlos Leyva Orasma, Jesús Jaime Benitez-Rivas, Juan Luis Morales Cruz, Cesar Alberto Meza-Herrera, Oscar Ángel-García, Fernando Arellano-Rodríguez, Guadalupe Calderón-Leyva, Dalia Ivette Carrillo-Moreno, Francisco Veliz Deras   +8 more
doaj   +1 more source