Results 61 to 70 of about 25,666 (269)

Salt-Responsive Metabolite, β-Hydroxybutyrate, Attenuates Hypertension

Cell Reports, 2018
Summary: Dietary salt reduction and exercise are lifestyle modifications for salt-sensitive hypertensives. While exercise has prominent metabolic effects, salt has an adverse effect on metabolic syndrome, of which hypertension is a hallmark.
Saroj Chakraborty, Sarah Galla, Xi Cheng, Ji-Youn Yeo, Blair Mell, Vishal Singh, BengSan Yeoh, Piu Saha, Anna V. Mathew, Matam Vijay-Kumar, Bina Joe   +10 more
doaj   +1 more source

Response of an Infant With Presumed Multiple Acyl‐CoA Dehydrogenase Deficiency (MADD) to Ketone Supplementation

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Multiple Acyl‐CoA Dehydrogenase Deficiency (MADD) is an autosomal recessive inborn error of metabolism caused by biallelic pathogenic variants in one of three known genes: ETFA, ETFB, and ETFDH. It can cause multisystem dysfunction, including cardiomyopathy in severe cases.
Yutaka Furuta, Kaitlyn N. Bloom, Jerry Vockley, Angela R. Grochowsky, Neena S. Agrawal, Ellen W. Strickler, Natalie N. Owen, Erica T. Gray, B. Lakshitha A. Perera, Eric R. Gamazon, Lynette C. Rives, Hua‐Chang Chen, Qi Liu, Rizwan Hamid, Joy D. Cogan, John A. Phillips III, Thomas A. Cassini, Bryce A. Schuler   +17 more
wiley   +1 more source

Cloning and expression of pullulanase gene from locally isolated bacillus SP [PDF]

, 2006
Bacterial pullulanase represents one of th e starch-degrading enzymes that are widely used in the starch processing indu stry along with amylases.
Hassan, Osman, Kamaruddin, Kamarulzaman, Md. Illias, Rosli, Md. Salleh, Madihah, Nik Mahmood, Nik Azmi, Shahab, Neelam   +5 more
core  

Anti-oxidant and anti-inflammatory activity of ketogenic diet. New perspectives for neuroprotection in alzheimer’s disease [PDF]

, 2018
The ketogenic diet, originally developed for the treatment of epilepsy in non-responder children, is spreading to be used in the treatment of many diseases, including Alzheimer’s disease.
Bonucci, Alessio, Businaro, Rita, Corsi, Mariangela, Maggi, Elisa, Pinto, Alessandro   +4 more
core   +1 more source

Exercise Factors Released by the Liver, Muscle, and Bones Have Promising Therapeutic Potential for Stroke

Frontiers in Neurology, 2021
Stroke is one of the leading causes of death and disability in the world. Stroke not only affects the patients, but also their families who serve as the primary caregivers.
Joseph S. Stephan, Sama F. Sleiman
doaj   +1 more source

Growth Hormone Promotes Lipolysis and Impairs Insulin Sensitivity by Activating the ERK/HSL Signaling Pathway in Bovine Adipocytes

Animal Research and One Health, EarlyView.
This study was to evaluate the role of GH in lipolysis and insulin sensitivity in bovine adipocytes and clarify the underlying mechanism. Our findings demonstrate that GH activates ERK/HSL signaling pathway, promotes lipolysis, and impairs insulin sensitivity in bovine adipocytes.
Xinxing Gao, Hao Yu, Erminio Trevisi, Cai Lin, Zhiyuan Fang, Xinwei Li, Yuxiang Song, Wenwen Gao, Lin Lei, Xiliang Du, Guowen Liu   +10 more
wiley   +1 more source

Serum Beta Hydroxybutyrate Concentrations in Cats with Chronic Kidney Disease, Hyperthyroidism, or Hepatic Lipidosis

Journal of Veterinary Internal Medicine, 2016
Background Ketones, including beta hydroxybutyrate (BHB), are produced in conditions of negative energy balance and decreased glucose utilization.
L. Gorman, L.C. Sharkey, P.J. Armstrong, K. Little, A. Rendahl   +4 more
doaj   +1 more source

Medium-Chain Fatty Acids, Beta-Hydroxybutyric Acid and Genetic Modulation of the Carnitine Shuttle Are Protective in a Drosophila Model of ALS Based on TDP-43

Frontiers in Molecular Neuroscience, 2018
ALS patients exhibit dyslipidemia, hypermetabolism and weight loss; in addition, cellular energetics deficits have been detected prior to denervation. Although evidence that metabolism is altered in ALS is compelling, the mechanisms underlying metabolic ...
Ernesto Manzo, Abigail G. O'Conner, Jordan M. Barrows, Dakotah D. Shreiner, Gabriel J. Birchak, Daniela C. Zarnescu, Daniela C. Zarnescu, Daniela C. Zarnescu   +7 more
doaj   +1 more source

Accumulation of poly-beta-hydroxybutyrate in Spirulina platensis. [PDF]

Journal of Bacteriology, 1982
Poly-beta-hydroxybutyrate has been identified in the cyanobacterium Spirulina platensis. The addition of reduced carbon compounds to the growth medium was not required for poly-beta-hydroxybutyrate accumulation. Poly-beta-hydroxybutyrate accumulated during exponential growth to 6% of the total dry weight and then decreased during the stationary phase.
J, Campbell, S E, Stevens, D L, Balkwill
openaire   +2 more sources

Compensation Response to Hepatic Gluconeogenesis via β‐Hydroxybutyrylation of FBP1 and PCK1 in Dairy Cows

Animal Research and One Health, EarlyView.
(1) Kbhb modification of FBP1 and PCK1 is involved in regulation of the gluconeogenesis pathway. (2) Kbhb of FBP1 and PCK1 is catalyzed by p300 and removed by HDACs. (3) BHB induced an increase in the enzymatic activity of FBP1 and PCK1 through Kbhb modification at the K43 site of FBP1 and the K191 site of PCK1.
DingPing Feng, GuoYan Wang, YuanYuan Zhu, YiNing Zheng, JunHu Yao, Lei Chen, Lu Deng   +6 more
wiley   +1 more source