Beta-lactam dose reductions in critically ill patients with acute kidney injury: a scoping review. [PDF]
Crit CareHorstink MMB +6 more
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Clinical Case Reports, Volume 14, Issue 8, August 2026.ABSTRACT Pan‐drug resistant Klebsiella pneumoniae is a major therapeutic challenge, particularly when standard last‐line agents are unavailable or contraindicated. We report a 45‐year‐old man with multifocal osteomyelitis and persistent purulent wound discharge despite broad‐spectrum antibiotics, repeated debridement, and two sequential amputations ...
Ali Akbar Heydari +2 more
wiley +1 more source
Achieving target plasma concentrations of beta-lactam antibiotics in critically ill patients: a retrospective study of full-dose administration in the first 24 hours. [PDF]
Pharmacol RepHalačová M +6 more
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The Visual Predictive Check and Real‐World Data
Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 394-398, August 2026.The visual predictive check (VPC) is a standard tool for assessing pharmacometric model suitability, producing visualizations that compare observed data with simulated data such that both model structure and model variability terms can be assessed. However, real‐world data commonly reflect clinical decision‐making that adapts therapy in response to ...
Jasmine H. Hughes +2 more
wiley +1 more source
Reply to Lai and Huang, "Which beta-lactam infusion strategy is superior in ICU pneumonia? A Bayesian network meta-analysis of continuous, extended, and intermittent approaches". [PDF]
Antimicrob Agents ChemotherLi Y +3 more
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Drug Development Research, Volume 87, Issue 5, August 2026.ABSTRACT Drug‐resistant bacteria such as Methicillin‐resistant Staphylococcus aureus (MRSA) and Quinolone‐resistant S. aureus (QRSA), are a growing problem, creating a need for the development of novel antimicrobial agents. In this study, we designed and synthesized two novel 1,4‐naphthoquinone derivatives, LHN‐1034 and LHN‐1035, and evaluated their ...
HyunChan Song +5 more
wiley +1 more source
eFood, Volume 7, Issue 4, August 2026.Plumbagin can be potentially used in combination with antibiotics, as a safer, and effective agent solution against biofilms formed by Staphylococcus aureus in the healthcare, and food industry. ABSTRACT Biofilm‐forming Staphylococcus aureus is the major cause several foodborne diseases, and pose a serious challenge in the healthcare, and food industry.
Borel Ndezo Bisso +5 more
wiley +1 more source
Proportion of carbapenem-resistant Enterobacterales with readily detectable beta-lactam resistance. [PDF]
Antimicrob Steward Healthc EpidemiolWilber E +3 more
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The Impact of Oral‐Gut Microbiota Structure and Its Manipulation on RA Development and Management
Food Science &Nutrition, Volume 14, Issue 8, August 2026.(A) Schematic representation of oral–gut microbiota composition in health and rheumatoid arthritis (RA), highlighting the enrichment of beneficial microorganisms (green) under healthy conditions and the expansion of pathogenic microorganisms (orange) in RA‐associated dysbiosis.
Parisa Ahmadi +8 more
wiley +1 more source
Evaluating extraction-free PCR for rapid detection of beta-lactam antibiotic resistance in urinary tract infection. [PDF]
Pract Lab MedAlmas S +8 more
europepmc +1 more source