Results 201 to 210 of about 89,494 (296)

Evaluating extraction-free PCR for rapid detection of beta-lactam antibiotic resistance in urinary tract infection. [PDF]

open access: yesPract Lab Med
Almas S   +8 more
europepmc   +1 more source

Epicutaneous and Drug Provocation Testing in Severe Cutaneous Adverse Reactions: A 20‐Year Single‐Centre Experience

open access: yesContact Dermatitis, Volume 94, Issue 6, Page 677-688, June 2026.
This study provides reassuring evidence in favour of early skin testing in patients with SCARs, argues against the necessity of a 6‐month delay, and underscores the pivotal role of oral provocation tests in the safe reintroduction of essential therapies. ABSTRACT Background Identifying and discontinuing the offending drug(s) in severe cutaneous adverse
Zohra Chadli   +8 more
wiley   +1 more source

Zwitterionic Penicillin‐Derived Sulfone Inhibitor for Combating β‐Lactamase‐Mediated Antibiotic Resistance

open access: yesChemMedChem, Volume 21, Issue 9, 14 May 2026.
Combining enhanced permeability strategies with (2‐pyridyl)methylene substitution in the sulbactam scaffold led to a novel β‐lactamase inhibitor to combat β‐lactamase‐mediated resistance to β‐lactam antibiotics. The studies presented highlight the potential of compound 3 as a next‐generation β‐lactamase inhibitor for combating infections caused by ...
Diana Rodríguez   +4 more
wiley   +1 more source

Proportion of carbapenem-resistant Enterobacterales with readily detectable beta-lactam resistance. [PDF]

open access: yesAntimicrob Steward Healthc Epidemiol
Wilber E   +3 more
europepmc   +1 more source

Total Synthesis of rac‐Keramamine C Enabled by Intrinsic H‐Bond‐Induced Conformational Fixation of Amides

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 18, 14 May 2026.
The total synthesis of the manzamine alkaloid keramamine C (2) in its racemic form was achieved in 5 steps, with ring‐closing metathesis as the key step. The metathesis is strongly improved by an intramolecular H‐bond‐induced conformational fixation of the amide bond, inducing close proximity of the terminal double bonds in the precursor molecule.
Jana Ganzmann   +4 more
wiley   +1 more source

Highly Versatile Hydrogenative Functionalizations of Phthalimides Catalyzed by an Ag‐Alumina Zeolite Nanocomposite: One‐Pot Synthesis of 3‐Substituted Isoindolinones

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.
Heterogeneous‐catalyzed selective and versatile hydrogenative functionalizations of phthalimides have been developed for the first time. By using a solid nanocomposite formed by [Ag/Al2O3] material in combination with [H‐BETA] zeolite as cocatalyst, a broad range of 3‐functionalized isoindolinones have been accesed in one‐pot from phthalimides, H2 and ...
Carles Lluna‐Galán   +2 more
wiley   +1 more source

Plasma Trough Concentrations of Beta-Lactam Antibiotics in the Early Phase of Septic Shock. [PDF]

open access: yesActa Anaesthesiol Scand
Hägglund M   +4 more
europepmc   +1 more source

Asymmetric Transformations of α,β‐Unsaturated Oxazolidinones Catalyzed by C2‐Symmetric Chiral Iron Triad Complexes

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.
This review highlights the evolution of highly enantioselective oxazolidinone transformations enabled by C2‐symmetric ligands, with emphasis on chiral iron triad complexes as cost‐effective, environmentally benign alternatives to late‐transition‐metal catalysts.
Arthur David, Thierry Ollevier
wiley   +1 more source

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