Results 191 to 200 of about 637,109 (288)

A Standards‐Based, Cloud‐Hosted CDS System for Gonorrhea Treatment and HIV Screening

Learning Health Systems, Volume 10, Issue 4, October 2026.
ABSTRACT Objective Neisseria gonorrhoeae (or gonococcus, GC) infections have increased in incidence and antibiotic resistance, prompting updates to management guidelines. Additionally, patients with recent GC infections have been identified as a target population for human immunodeficiency virus (HIV) screening and prevention. With the rapidly changing
Edna Shenvi, Aziz Boxwala, Sarah Shaw, Andre Berro, Saugat Karki, Matthew Pooser, Jane E. Yang, Gema Dumitru, Jeanne Ocampo, Amrita Tailor, Sanjat Kanjilal, Carlos Paredes, Ritche Hao, Nitu Kashyap, David Liebovitz, Alejandro Pérez   +15 more
wiley   +1 more source

Effects of CwlM, a peptidoglycan synthesis regulator, on beta-lactam tolerance and host-pathogen interactions. [PDF]

BMC Microbiol
Silveiro C, Mortinho D, Olivença F, Mandal M, Pires D, Anes E, Catalão MJ.   +6 more
europepmc   +1 more source

Prevalence and Characteristics of Salmonella spp. by Production Stage in Integrated Broiler Operations in Korea

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Vertically integrated broiler production systems may facilitate the dissemination of Salmonella throughout the production chain. This study demonstrates that Salmonella persists and spreads across all stages of integrated broiler production, highlighting the need for rigorous biosecurity, hygiene and continuous monitoring throughout the entire ...
Hyeong Jeong Choi, Young Ju Lee
wiley   +1 more source

Chemical Optimization of Temporin A–L Peptides: From Native Isoforms to Enhanced Antimicrobial Analogs

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Temporins, among antimicrobial peptides, are short frog‐derived molecules with potent antibacterial activity. This review highlights chemical optimization strategies applied to temporins A–L, showing how sequence tuning modulates structure, stability, and selectivity, enabling improved activity against resistant pathogens.
Ida Boccino, Paolo Grieco, Francesco Merlino   +2 more
wiley   +1 more source

Impact of Extending Beta-Lactam Infusions on IV Access Requirements. [PDF]

Crit Care Explor
Kooda KJ, Nelson J, Ausman SE, Rivera CG, Abu Saleh OM, Rule AD, Stevens RW, Warfield MN, Zhao Y, Barreto EF, Beta Lactam Optimization and Outcomes Management (BLOOM) Study Group.   +10 more
europepmc   +1 more source

Visible‐Light Photoredox Catalysis in the Intramolecular Dicarbonylation of Alkenes: Catalyst‐Dependent Divergent Syntheses of Both 1,4‐Dicarbonyls and α‐Hydroxy‐β,γ‐Unsaturated Lactams From 1,2‐Dicarbonyls

Advanced Synthesis &Catalysis, Volume 368, Issue 15, 1 August 2026.
Catalyst‐dependent divergent syntheses were developed. Intramolecular dicarbonylation of vinyl halides under metal‐free either thermal or visible light photocatalytic conditions were explored to produce a series of 1,4‐dicarbonyls with two different carbonyl moieties and a lactam ring.
Chia‐Lin Li, Che‐Chien Chang
wiley   +1 more source

Isolation, characterisation and potential applications of a novel bacteriophage targeting beta-lactam-resistant Staphylococcus saprophyticus. [PDF]

Sci Rep
Gopika O, Sarat N, Manikandan M, Sumana S, Mohanan PCP, Madhavan A, Varma RS, Mahapatra S, Nair BG, Pal S.   +9 more
europepmc   +1 more source

Chemoenzymatic Synthesis of Chiral Piperidines Using the Immobilized Transaminase ATA‐117 in Continuous Flow Reactors

Advanced Synthesis &Catalysis, Volume 368, Issue 15, 1 August 2026.
A robust continuous flow chemoenzymatic process was developed for the stereoselective synthesis of cis‐(2R,6R)‐2,6‐disubstituted piperidines, including the natural alkaloid (–)‐pinidinone. The asymmetric transamination of α,β‐unsaturated ketones was catalyzed by immobilized ATA‐117, followed by spontaneous aza‐Michael cyclization, providing the desired
Sara Vicinanza, Ilaria Magrini Alunno, Stefania Patti, Morena Pirotta, Francesca Annunziata, Raffaella Gandolfi, Paola Conti, Chiara Borsari, Ivan Bassanini, Erica Elisa Ferrandi, Daniela Monti, Lucia Tamborini   +11 more
wiley   +1 more source

Authors' response to comment on evaluation of high dose post-dialytic versus daily beta-lactam dosing in hemodialysis patients using Monte Carlo simulation. [PDF]

Int J Clin Pharm
Lewis SJ, Bauman AJ, Caiazza OG, Wan N, Payer S, Pauly OG, Shoemaker S.   +6 more
europepmc   +1 more source

The Development and Validation of a Simple Method for the Determination of Meropenem Concentrations in Human Plasma Using High‐Performance Liquid Chromatography

Applied Research, Volume 5, Issue 4, August 2026.
A simple, rapid, and sustainable HPLC‐UV method was developed and validated to quantify meropenem in human plasma across a wide linear range (0.5–100 mg/L). Utilizing an efficient one‐step protein precipitation, this eco‐friendly approach is highly suited for routine clinical therapeutic drug monitoring and research purposes.
Asma Aboelezz, Maged Kharouba, Sherif Hanafy Mahmoud   +2 more
wiley   +1 more source