Results 111 to 120 of about 40,704 (257)

Anterolateral‐Thigh Fascia Lata Free Flap Versus Fibula Free Flap for Mandibular Osteoradionecrosis

open access: yesThe Laryngoscope, Volume 136, Issue 6, Page 2565-2572, June 2026.
The anterolateral thigh fascia lata “rescue” free flap has been employed as a novel tool in the treatment of advanced partial thickness mandibular osteoradionecrosis. Compared with the traditional fibula free flap for the same indication, the “rescue” flap provides similar outcomes in terms of disease resolution, superior functional outcomes, and ...
Conrad K. Blunck   +8 more
wiley   +1 more source

Pharmacokinetic Analysis of Intravenous Push Cefepime in Critically Ill Patients With Sepsis

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 6, June 2026.
ABSTRACT Background Intravenous push (IVP) administration of cefepime increases ease of preparation and limits the need for small volume parenterals. The data on IVP pharmacokinetic/pharmacodynamic (PK/PD) parameters are limited, but may be especially relevant in critically ill patients with altered PK/PD for time‐dependent antibiotics like cefepime ...
Susan E. Smith   +8 more
wiley   +1 more source

β-lactam hypersensitivity involves expansion of circulating and skin-resident Th22 cells [PDF]

open access: yes, 2017
Background: β-lactam hypersensitivity has been classified according to the phenotype and function of drug-specific T-cells; however, new T-cell subsets have not been considered.
Andrew Sullivan   +49 more
core   +2 more sources

Epicutaneous and Drug Provocation Testing in Severe Cutaneous Adverse Reactions: A 20‐Year Single‐Centre Experience

open access: yesContact Dermatitis, Volume 94, Issue 6, Page 677-688, June 2026.
This study provides reassuring evidence in favour of early skin testing in patients with SCARs, argues against the necessity of a 6‐month delay, and underscores the pivotal role of oral provocation tests in the safe reintroduction of essential therapies. ABSTRACT Background Identifying and discontinuing the offending drug(s) in severe cutaneous adverse
Zohra Chadli   +8 more
wiley   +1 more source

Vancomycin use in a brazilian teaching hospital: comparison with the Hospital Infection Controlpractices Advisory Committee Guidelines (HICPAC) [PDF]

open access: yes
This study describes vancomycin prescribing patterns in an average complexity hospital and compare the guidelines proposed by the Hospital Infection Control Practices Advisory Committee (HICPAC).
MELO, Daniela Oliveira de   +1 more
core   +1 more source

Adverse drug reaction and toxicity caused by commonly used antimicrobials in canine practice [PDF]

open access: yes, 2014
An adverse drug reaction (ADR) is a serious concern for practicing veterinarians and other health professionals, and refers to an unintended, undesired and unexpected response to a drug that negatively affects the patient's health.
Barranco   +10 more
core   +1 more source

Institutional Trends in Penicillin Allergy: A New Era of Active Penicillin Allergy Delabeling

open access: yes
Clinical &Experimental Allergy, EarlyView.
Anna Brameli   +14 more
wiley   +1 more source

Time‐dependent wound management protocol prevents periprosthetic joint infection in total knee arthroplasty with persistent drainage

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, Volume 34, Issue 5, Page 1740-1749, May 2026.
Abstract Purpose This study aimed to evaluate the success rate of a standardised protocol for managing persistent wound drainage following total knee arthroplasty (TKA). Methods A prospective observational study was conducted at four institutions between January and June 2022 across primary and revision TKAs.
Filippo Leggieri   +8 more
wiley   +1 more source

Introduction of a penicillin allergy de-labelling program with direct oral challenge and its effects on utilization of beta-lactam antimicrobials: a multicenter retrospective parallel cohort study

open access: yesAllergy, Asthma & Clinical Immunology
Background Self-reported penicillin allergy labels are common and often inaccurate after assessment. These labels can lead to reduced use of first-line beta-lactam antibiotics and worse outcomes. We measured the impact of a previously performed inpatient
Adhora Mir   +6 more
doaj   +1 more source

Efficacy of Non-Beta-lactam Antibiotics for Prevention of Cesarean Delivery Surgical Site Infections

open access: yesAmerican Journal of Perinatology Reports, 2019
Objective To examine the association between perioperative Beta (β))-lactam versus non-β-lactam antibiotics and cesarean delivery surgical site infection (SSI).
Benjamin S. Harris   +8 more
doaj   +1 more source

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