Results 271 to 280 of about 153,260 (300)

Beta lactamase inhibitors

Clinical Microbiology Newsletter, 1988
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Evolution of beta-lactamase inhibitors.

Pharmacotherapy, 1991
After the introduction of penicillin G into therapeutics, bacteria became increasingly resistant to this penicillin and subsequent beta-lactam antibiotics. The major cause of this resistance is beta-lactamase, an enzyme produced by the bacterium, that destroys the antibiotic before it reaches its target within the bacterial cell.
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Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates.

Journal of Medicinal Chemistry, 2004
A. Venkatesan, Yansong Gu, O. dos Santos, T. Abe, A. Agarwal, Youjun Yang, P. Petersen, W. Weiss, T. Mansour, M. Nukaga, A. Hujer, R. Bonomo, J. Knox   +12 more
semanticscholar   +1 more source

Resistance to beta-lactam antibiotics: structure and mechanism based design of beta-lactamase inhibitors.

Current Medicinal Chemistry, 2002
V. Sandanayaka, Amar S. Prashad
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[Beta-lactamase inhibitors].

Nihon rinsho. Japanese journal of clinical medicine, 1992
H, Nishiya, O, Kunii
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Clinical isolates of Escherichia coli producing multiple TEM mutants resistant to beta-lactamase inhibitors.

Journal of Antimicrobial Chemotherapy, 1994
D. Sirot, C. Chanal, Cécile Henquell, R. Labia, J. Sirot, R. Cluzel   +5 more
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Implications of beta-lactamase-inhibitor combinations.

The Journal of reproductive medicine, 1988
Ticarcillin disodium/clavulanate potassium and other beta-lactamase inhibitor/penicillin combinations have been recognized recently as broad-spectrum drugs that have a major role in chemotherapy for serious surgical sepsis. Their spectrum of activity allows the economical substitution of ticarcillin disodium/clavulanate potassium for anaerobe-active ...
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Structure-activity relationship of 6-methylidene penems bearing 6,5 bicyclic heterocycles as broad-spectrum beta-lactamase inhibitors: evidence for 1,4-thiazepine intermediates with C7 R stereochemistry by computational methods.

Journal of Medicinal Chemistry, 2006
A. Venkatesan, A. Agarwal, T. Abe, Hideki Ushirogochi, I. Yamamura, M. Ado, Takasaki Tsuyoshi, O. dos Santos, Ya-Nan Gu, F. Sum, Zhong Li, G. Francisco, Yang-i Lin, P. Petersen, Youjun Yang, T. Kumagai, W. Weiss, D. Shlaes, J. Knox, T. Mansour   +19 more
semanticscholar   +1 more source

Beta-lactamase inhibitors: the story so far.

Current Medicinal Chemistry, 2009
F. Pérez-Llarena, G. Bou
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Beta-lactamase inhibitors

2006
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