Results 261 to 270 of about 1,753,858 (323)

Beta-Lactamases and ESBL

Virology & Immunology Journal, 2019
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Cryoenzymology of .beta.-lactamases

Biochemistry, 1987
The cryoenzymology of several different beta-lactamases has been investigated. Particular attention has been paid to the experimental pitfalls of the technique. These include such factors as false bursts at the start of the reaction, instability of the enzymes during turnover, and Km values so high that little of the enzyme is present as a complex ...
S J, Cartwright, S G, Waley
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beta-lactamase epidemiology and the utility of established and novel beta-lactamase inhibitors

Expert Opinion on Investigational Drugs, 2000
beta-Lactamase inhibitor:beta-lactam combinations remain one of the most successful strategies for the treatment of bacterial infections. Over the last 20 years the number and diversity of serine and metallo active site beta-lactamases has increased dramatically. This review highlights some of the new additions to the beta-lactamase arena and discusses
D J, Payne, W, Du, J H, Bateson
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Beta-Lactamase Inhibitors and the Inducibility of the Beta-Lactamase of Mycobacterium tuberculosis

American Review of Respiratory Disease, 1992
Abstract Ten clinical isolates and the type strain (H37Rv) of Mycobacterium tuberculosis were shown to produce an intracellular β-lactamase. Crude enzyme preparations were extracted from acetone cell powders by grinding with zirconium beads in 0.133 M glycine with 1.0% Triton X-100.
Y, Zhang, V A, Steingrube, R J, Wallace
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Effect of beta-lactamase inhibitors on beta-lactamases from anaerobic bacteria

European Journal of Clinical Microbiology & Infectious Diseases, 1992
Three beta-lactamase inhibitors in clinical use--clavulanic acid, sulbactam and tazobactam--were investigated for their activity on beta-lactamases from Bacteroides uniformis, Clostridium butyricum and Fusobacterium nucleatum. Purification of the beta-lactamases was carried out by anion-exchange chromatography, gel filtration and FPLC. The inactivation
M, Hedberg, L, Lindqvist, K, Tunér, C E, Nord   +3 more
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Beta-Lactamase Stability of Faropenem

Chemotherapy, 2003
Faropenem (FAR) is an orally available member of the penem class unique among carbapenems and other available β-lactams. This study compared FAR to cephalosporins and imipenem with respect to β-Iactamase (BLA) stability and emergence of resistance to <i>Staphylococcus aureus </i>and <i>Escherichia coli</i>.
A, Dalhoff, T, Nasu, K, Okamoto
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Importance of beta-lactamase induction

European Journal of Clinical Microbiology & Infectious Diseases, 1993
Induction of an enzyme is a temporary phenomenon in which the rate of enzyme synthesis is greatly increased in response to the presence of an inducer in the environment. Induction of beta-lactamase synthesis is important for the resistance of staphylococci to penicillins since the drug both induces synthesis of the enzyme and is hydrolysed by it ...
I, Phillips, K, Shannon
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