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beta-lactamases in bacteroides.
Scandinavian journal of infectious diseases. Supplementum, 1978Bacteroides fragilis is responsible for most anaerobic infections in man. Most isolates of B. fragilis show resistance to beta-lactam antibiotics. This resistance might be due to beta-lactamase production or permeability barrier in the cell wall. B. fragilis produce beta-lactamase with mainly cephalosporinase activity. Other Bacteroides species such as
C E, Nord, B, Olsson, K, Dornbusch
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The Chromosomal Beta-Lactamases
1989Virtually all gram-negative bacteria studied to date produce a chromosomal betalactamase. Thus, it is not surprising that there is a great diversity among these enzymes in substrate profile, susceptibility to inhibitors, genetic control of expression and molecular makeup.
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