Results 201 to 210 of about 1,317,896 (291)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Mowing Modulates the Biotic Filter of Expansive Species. [PDF]

Ecol Evol
Bricca A, Cangelmi G, Ferrara A.
europepmc   +1 more source

Antioxidant activity of dandang gendis leaf extracts Clinacanthus nutans L. ethyl acetate solvent on free radical inhibition and increasing number of pancreas beta cells [PDF]

Syahida Djasang, Artati Artati
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Transcriptomic Insights into the Molecular Responses of Red Imported Fire Ants (<i>Solenopsis invicta</i>) to Beta-Cypermethrin and <i>Cordyceps cicadae</i>. [PDF]

Genes (Basel)
Cai R, Li X, Chai Y, Liu Z, Pan Y, Liu Y.   +5 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

WHO priority pathogens, ESKAPE bacteria, and antimicrobial resistance surveillance in household wastewater, Gombe, Nigeria. [PDF]

Access Microbiol
Muhammad Z, Adamu MT, Garba L, Abdullahi Tawfiq U, Yusuf I.   +4 more
europepmc   +1 more source

Number representation using generalized $(-\beta)$-transformation [PDF]

, 2011
Daniel Dombek, Zuzana Masáková, Edita Pelantová   +2 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Synthesis, characterisation and evaluation of polyethylene glycol-β-cyclodextrin-curcumin-zinc oxide nanoparticles for mosquitocidal, antibacterial and anticancer applications. [PDF]

Sci Rep
Suresh U, Panneerselvam C, Aziz AT, Srinivasan MK, Hassan MM, Alasmari A, Mohammedsaleh ZM.   +6 more
europepmc   +1 more source