Results 31 to 40 of about 19,991 (232)

Implantation of silicon dioxide-based nanocrystalline hydroxyapatite and pure phase beta-tricalciumphosphate bone substitute granules in caprine muscle tissue does not induce new bone formation

, 2013
Background: Osteoinductive bone substitutes are defined by their ability to induce new bone formation even at heterotopic implantation sites. The present study was designed to analyze the potential osteoinductivity of two different bone substitute ...
Künzel, Oliver, Shahram Ghanaati, Ines Willershausen, Ghanaati, Shahram Michael, Samuel E. Udeabor, Robert A. Sader, Oliver Kuenzel, Sader, Robert Alexander, Udeabor, Samuel Ebele, Kirkpatrick, Charles James, C. James Kirkpatrick, Willershausen, Ines Bettina Anne, Mike Barbeck, Barbeck, Mike   +13 more
core   +1 more source

Co-grinding significance for calcium carbonate–calcium phosphate mixed cement. Part I: effect of particle size and mixing on solid phase reactivity [PDF]

, 2011
In part I of this study we aim to evaluate and control the characteristics of the powders constituting the solid phase of a vaterite CaCO3–dicalcium phosphate dihydrate cement using a co-grinding process and to determine their impact on cement setting ...
Combes, Christèle, Le Bolay, Nadine, Tadier, Solène, C. Rey, Rey, Christian, S. Tadier, N. Le Bolay, C. Combes   +7 more
core   +1 more source

Microwave sintering of nano size powder β-TCP bioceramics [PDF]

Science of Sintering, 2014
A nano sized beta tricalcium phosphate (β-TCP) powder was conventional sintered (CS) and microwave sintered (MW), in order to obtain dense β-TCP ceramics.
Mirhadi B.
doaj   +1 more source

The influence of bone substitute material on mechanical properties of trabecular bone in augmentation of intra-articular impression fractures. Experimental study [PDF]

Гений oртопедии, 2018
The purpose was to evaluate the effect of bone substitute materials on mechanical properties of trabecular bone adjacent to the joint. Material and methods A total of 21 female chinchilla rabbits weighing 3-3.5 kg was used for the experimental study.
Mikhail V. Gilev, Dmitry V. Zaytsev, Mariia Yu. Izmodenova, Daria V. Kiseleva, Elena A. Volokitina   +4 more
doaj   +1 more source

Effect of sonic hedgehog/β-TCP composites on bone healing within the critical-sized rat femoral defect

, 2013
The creation of entirely synthetically derived bone substitute materials which are as effective as autologous bone grafts is desirable. Osteogenesis involves the concerted action of several proteins within a signaling cascade.
Henrich, Dirk, Marzi, Ingo, Seebach, Caroline, Flinspach, Armin Niklas, Wenger, Florian, Warzecha, Jörg   +5 more
core   +1 more source

A Fully Human Engineered Bone Niche With Endogenous Osteoclastogenesis Reveals Osteoclast‐Dependent Osteomimicry in Prostate Cancer Cells

Advanced Healthcare Materials, EarlyView.
A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni, Robin Dolgos, Thomas Menter, Boris Dasen, Arnaud Scherberich, Clémentine Le Magnen, Manuele G. Muraro, Ivan Martin   +7 more
wiley   +1 more source

Standardized Effect Measures Informing Next‐Generation Strategies for Mechanical Stimulation in Cartilage Tissue Engineering

Advanced Healthcare Materials, EarlyView.
This systematic review quantitatively compares conventional mechanical stimulation strategies in cartilage tissue engineering across 85 heterogeneous in vitro studies. Applying standardized effect measures, meta‐analysis reveals that combined compression and shear loading optimally promotes cartilage matrix development.
Jiaqi K. Shen, Tony B. Huang, Catherine E. Davey, Elias Salzer, Gerjo J. V. M. Van Osch, Sandra J. Shefelbine, Marcus G. Pandy, Kathryn S. Stok   +7 more
wiley   +1 more source

Surgical Treatment of Periodontal Intrabony Defects with Calcium Sulphate in Combination with Beta-Tricalcium Phosphate: Clinical Observations Two Years Post-Surgery

Acta Medica, 2011
The study was designed to evaluate the clinical outcome of a composite material, beta-tricalcium phosphate in combination with calcium sulphate, in the treatment of periodontal intrabony defects.
Sujith Sukumar, Ivo Dřízhal, Vladimíra Paulusová, Josef Bukač   +3 more
doaj   +1 more source

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source