Results 91 to 100 of about 4,641,185 (396)

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

The orbit of a $β$-transformation cannot lie in a small interval [PDF]

Journal of the Korean Mathematical Society 49 (2012), no. 4, 867-879
For $\beta>1$, let $T_\beta:[0,1]\rightarrow [0,1)$ be the $\beta$-transformation. We consider an invariant $T_\beta$-orbit closure contained in a closed interval with diameter $1/\beta$, then define a function $\Xi(\alpha,\beta)$ by the supremum of such $T_\beta$-orbit with frequency $\alpha$ in base $\beta$, i.e., the maximum value in the $T_\beta ...
arxiv   +1 more source

Sistem Persamaan Linear Fuzzy [PDF]

, 2008
Let AU = V be fuzzy system of linear equations. The fuzzy system of linear equations consist of n variables and n equations.We rearrange the fuzzy system of linear equations became 2n variables and 2n equations. The new system was devoted by BX* = V*. In
Noeranita, B. (Beta)
core  

Socially Mediated Publicness in Networked Society for Indonesian Muslim Women [PDF]

, 2016
: This paper addresses discursive processes that generated ‘jilboobs\u27 term. It tries to ground the notion of socially mediated publicness and its affordances by investigating the process of image making of Indonesian Muslim women.
Beta, A. R. (Annisa)
core   +4 more sources

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Prospective impacts of windstorm risk on carbon sinks and the forestry sector: an integrated assessment with Monte Carlo simulations

Environmental Research Letters
Storms pose a significant threat to economic activities in the forest sector and introduce non-permanence risks for carbon stocks. Following escalating climate ambitions, understanding and addressing these risks becomes imperative.
Félix Bastit, Miguel Riviere, Antonello Lobianco, Philippe Delacote   +3 more
doaj   +1 more source

Bromodomain Protein Inhibition Protects β-Cells from Cytokine-Induced Death and Dysfunction via Antagonism of NF-κB Pathway

Cells
Cytokine-induced β-cell apoptosis is a major pathogenic mechanism in type 1 diabetes (T1D). Despite significant advances in understanding its underlying mechanisms, few drugs have been translated to protect β-cells in T1D.
Vinny Negi, Jeongkyung Lee, Varun Mandi, Joseph Danvers, Ruya Liu, Eliana M. Perez-Garcia, Feng Li, Rajaganapati Jagannathan, Ping Yang, Domenic Filingeri, Amit Kumar, Ke Ma, Mousumi Moulik, Vijay K. Yechoor   +13 more
doaj   +1 more source

Theory of open quantum dynamics with hybrid noise

New Journal of Physics, 2018
We develop a theory to describe dynamics of a non-stationary open quantum system interacting with a hybrid environment, which includes high-frequency and low-frequency noise components. One part of the system–bath interaction is treated in a perturbative
Anatoly Yu Smirnov, Mohammad H Amin
doaj   +1 more source

NEED ANALYSIS FOR IDENTIFYING ESP MATERIALS FOR MEDICAL RECORD STUDENTS IN APIKES CITRA MEDIKA SURAKARTA

Kajian Linguistik dan Sastra, 2016
Identifying teaching material is the process of  selecting, adapting and evaluating of teaching based on specific necessities of the students. Need Analysis is really needed to identify teaching materials for  English for Specific Purpose.
Beta Setiawati
doaj   +1 more source

Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease.

New England Journal of Medicine, 1996
BACKGROUND Observational studies suggest that people who consume more fruits and vegetables containing beta carotene have somewhat lower risks of cancer and cardiovascular disease, and earlier basic research suggested plausible mechanisms.
C. Hennekens, Julie E. Buring, J. Manson, M. Stampfer, B. Rosner, N. Cook, C. Belanger, F. LaMotte, J. Gaziano, P. Ridker, W. Willett, R. Peto   +11 more
semanticscholar   +1 more source