Results 201 to 210 of about 153,861 (252)

Correlation between beta-2-glycoprotein I gene polymorphism and anti-beta-2 glycoprotein I antibodies in patients with multibacillary leprosy

Archives of Dermatological Research, 2010
Antiphospholipid antibodies, such as anti-beta2-glycoprotein I (beta2GPI), are present in multibacillary leprosy (MB) patients; however, MB patients do not usually present with antiphospholipid antibody syndrome (APS), which is characterized by thromboembolic phenomena (TEP).
Maria José Franco, Brochado, José Fernando C, Figueiredo, Celso Teixeira, Mendes-Junior, Paulo, Louzada-Junior, Olivia Makiyama, Kim, Ana Maria, Roselino   +5 more
openaire   +2 more sources

[Antiphospholipid and anti beta 2-glycoprotein I antibodies].

Annales de biologie clinique, 1995
Recent studies have shown that beta 2glycoprotein I (beta 2GPI), a plasma inhibitor of coagulation with affinity for anionic phospholipids, is frequently required for the formation of the epitopes recognized by some anti-phospholipid antibodies.
J, Arvieux, B, Roussel, M G, Colomb
openaire   +2 more sources

IgA anti-beta-2 glycoprotein I antibodies in chronic hepatitis C

Arab Journal of Gastroenterology, 2022
Antiphospholipid antibodies (aPL) have been reported not only in various autoimmune conditions but also in other infections, such as chronic hepatitis C (CHC) infection. The aim of this study is to evaluate the frequency of aPL in patients with CHC.Ninety-six CHC patients and 90 healthy blood donors (HBD) were studied.
Sarra, Melayah, Ouafa, Kallala, Mariem, Ben Ahmed, Imen, Fodha, Saloua, Yacoub Jemni, Ibtissem, Ghedira, Amani, Mankaï   +6 more
openaire   +2 more sources

Beta-2-glycoprotein-I, infections, antiphospholipid syndrome and therapeutic considerations

Clinical Immunology, 2004
Evidence supports the association between infectious agents, antiphospholipid syndrome (APS), and the presence of antiphospholipid antibodies and anti-beta2-glycoprotein-I (beta2GPI) antibodies. Several mechanisms have been proposed to explain the role of bacteria/viruses in induction of an autoimmune condition, such as molecular mimicry between ...
Miri, Blank, Yehuda, Shoenfeld
openaire   +2 more sources

Anti-β 2 -Glycoprotein I Autoantibodies and Atherosclerosis

International Reviews of Immunology, 2002
beta 2-Glycoprotein I (beta 2-GPI) is a major antigen for antiphospholipid antibodies (aPL) present in patients with antiphospholipid syndrome (APS). We previously reported that beta 2-GPI specifically binds to oxidized low-density lipoprotein (oxLDL).
Eiji, Matsuura, Kazuko, Kobayashi, Junko, Kasahara, Tatsuji, Yasuda, Hirofumi, Makino, Takao, Koike, Yehuda, Shoenfeld   +6 more
openaire   +2 more sources

beta 2-Glycoprotein I and anti-beta 2-glycoprotein I antibodies: where are we now?

British journal of rheumatology, 1998
beta 2-Glycoprotein I (beta 2-GPI), a plasma protein with in vitro anticoagulant properties, has been recognized to have an important role in the antiphospholipid syndrome (APS) as a cofactor and an (co)antigen in ELISA assays. Although beta 2-GPI levels were found to be increased in some patients with APS, the clinical value of measuring beta 2-GPI ...
M, Inanç, E L, Radway-Bright, D A, Isenberg   +2 more
openaire   +1 more source

Anticardiolipin Antibody and Anti-beta 2 Glycoprotein I Antibody Assays

2013
Antiphospholipid syndrome (APS) is an autoimmune disease and is a risk factor for a number of clinical manifestations; the classic presentations include fetal death or thrombosis (arterial or venous thromboembolism), in the presence of persistently increased titers of antiphospholipid (aPL) antibodies.
Anne, Raby, Karen, Moffat, Mark, Crowther   +2 more
openaire   +2 more sources

Anti-beta 2-glycoprotein I autoantibodies from patients with the "antiphospholipid" syndrome bind to beta 2-glycoprotein I with low affinity: dimerization of beta 2-glycoprotein I induces a significant increase in anti-beta 2-glycoprotein I antibody affinity.

Journal of immunology (Baltimore, Md. : 1950), 1998
"Antiphospholipid" autoantibodies are associated with arterial and venous thrombosis, recurrent fetal loss, and thrombocytopenia. At present, the best-characterized antigenic target for these autoantibodies (or Abs) is the phospholipid-binding protein beta2-glycoprotein I (beta2GPI).
Y, Sheng, D A, Kandiah, S A, Krilis
openaire   +1 more source

Consensus guidelines on anti-beta 2 glycoprotein I testing and reporting

Pathology, 2008
Consensus guidelines on anti-beta 2 glycoprotein I (anti-beta2GPI) testing have been developed to help minimise laboratory variation in the performance and reporting of assays for these antibodies. These guidelines include minimum and optional recommendations for the following aspects of anti-beta2GPI testing and reporting: (1) isotype of anti-beta2GPI
R C W, Wong, E J, Favaloro, S, Adelstein, K, Baumgart, R, Bird, T A, Brighton, M, Empson, D, Gillis, M J, Hendle, R, Laurent, D, Mallon, W, Pollock, S, Smith, R H, Steele, R J, Wilson   +14 more
openaire   +2 more sources

Beta 2-glycoprotein I--a Bi-Allelic polymorphism.

Acta anthropogenetica, 1981
Population samples from Hungary and India have been typed for beta 2-glycoprotein I concentrations. Whereas the Hungarian sample is in fairly good accord with the genetic model set up by Cleve2-beta 2-glycoprotein I concentrations are controlled by two autosomal codominant alleles BgN and BgD-the Indian samples do not fit this model.
H, Walter, R, Schliwa, H, Lankenau, I P, Singh, M K, Bhasin, P, Veerraju, J D, Goud, J, Nemeskeri   +7 more
openaire   +1 more source