Results 281 to 290 of about 267,362 (329)

Beta-2-glycoprotein-I IgA antibodies predict coronary plaque progression in rheumatoid arthritis.

Seminars in Arthritis & Rheumatism, 2020
OBJECTIVES To evaluate whether anti-Beta-2-Glycoprotein-I (anti-β2GPI) IgA antibodies associate with progression of coronary atherosclerosis and cardiovascular disease (CVD) events in rheumatoid arthritis (RA).
G. Karpouzas, S. Ormseth, E. Hernandez, Viet L Bui, M. Budoff   +4 more
semanticscholar   +1 more source

Avidity of anti-beta-2-glycoprotein I antibodies

Autoimmunity Reviews, 2005
The terms affinity and avidity are often used indiscriminately, despite clearly differing. Since affinity refers to monovalent binding of antibodies to a monovalent epitope, the majority of data on the binding of anti-beta2-glycoprotein I antibodies (anti-beta2-GPI) characterized their avidity rather than affinity.
B, Bozic, S, Cucnik, T, Kveder, B, Rozman   +3 more
openaire   +2 more sources

B cell-derived anti-beta 2 glycoprotein I antibody contributes to hyperhomocysteinemia-aggravated abdominal aortic aneurysm.

Cardiovascular Research, 2019
AIMS Overactivated B cells secrete pathological antibodies, which in turn accelerate the formation of abdominal aortic aneurysms (AAAs). Hyperhomocysteinemia (HHcy) aggravates AAA in mice; however, the underlying mechanisms remain largely elusive.
Fangyu Shao, Yutong Miao, Yan Zhang, Lulu Han, Xiaolong Ma, Jiacheng Deng, Changtao Jiang, W. Kong, Qingbo Xu, Juan Feng, Xian Wang   +10 more
semanticscholar   +1 more source

Are concentrations of clusterin and beta-2-glycoprotein I dysregulated in HIV associated preeclampsia?

European Journal of Obstetrics, Gynecology, and Reproductive Biology, 2020
OBJECTIVE To evaluate the levels of serum beta-2-glycoprotein I (β2GP1) and clusterin in the duality of Pre-eclampsia and HIV. METHOD Stored serum samples collected from 72 pregnant women were stratified according to the pregnancy type (pre-eclamptic ...
Zinhle P. Mlambo, Deneshree Varaden, J. Moodley, T. Naicker   +3 more
semanticscholar   +1 more source

Beta-2-glycoprotein I Dependent Lupus Anticoagulants Form Stable Bivalent Antibody Beta-2-Glycoprotein I Complexes on Phospholipid Surfaces

Thrombosis and Haemostasis, 1998
SummaryThe precise mechanism by which Beta-2-glycoprotein I (β2GPI-) dependent lupus anticoagulants lengthen phospholipid-dependent clotting reactions is still poorly understood. In order to study this, murine monoclonal antibodies (moabs) against human β2GPI were raised. Eight of the 21 anti-β2GPI moabs, obtained from 2 fusions, fulfilled the criteria
J, Arnout, C, Wittevrongel, M, Vanrusselt, M, Hoylaerts, J, Vermylen   +4 more
openaire   +2 more sources

Synchronized inhibition of the phospholipid mediated autoactivation of factor XII in plasma by beta 2-glycoprotein I and anti-beta 2-glycoprotein I.

Thrombosis and haemostasis, 1995
Lupus anticoagulants are a group of antibodies commonly found in patients with autoimmune diseases such as systemic lupus erythematosus. Lupus anticoagulants inhibit phospholipid dependent coagulation and may bind to negatively charged phospholipids.
I, Schousboe, M S, Rasmussen
openaire   +2 more sources

Beta 2 glycoprotein I is a substrate of thiol oxidoreductases

Blood, 2010
To the editor: Beta 2 glycoprotein I (β2GPI) is an abundant plasma protein recognized as the major autoantigen in the antiphospholipid syndrome. Although the crystal structure of β2GPI has been resolved,[1][1],[2][2] its normal function remains unknown.
Gemmell, Rosalie, Passam, Freda H., Rahgozar, Soheila, Qi, Miao, Raftery, Mark J., Wong, Jason W.H., Tanaka, Kumiko, Ioannou, Yiannis, Zhang, Jing Yun, Qi, Jian Chen, Giannakopoulos, Bill, Hughes, Will E., Hogg, Philip J., Krilis, Steven A.   +13 more
openaire   +3 more sources

beta 2-Glycoprotein I and anti-beta 2-glycoprotein I antibodies: where are we now?

British journal of rheumatology, 1998
beta 2-Glycoprotein I (beta 2-GPI), a plasma protein with in vitro anticoagulant properties, has been recognized to have an important role in the antiphospholipid syndrome (APS) as a cofactor and an (co)antigen in ELISA assays. Although beta 2-GPI levels were found to be increased in some patients with APS, the clinical value of measuring beta 2-GPI ...
M, Inanç, E L, Radway-Bright, D A, Isenberg   +2 more
openaire   +1 more source

Beta 2-glycoprotein I deficiency and the risk of thrombosis.

Thrombosis and haemostasis, 1992
beta 2-glycoprotein I (beta 2-GP I) is a plasma protein with a high affinity for negatively charged surfaces. In vitro this protein shows a variety of anticoagulant properties (inhibition of contact activation and platelet dependent prothrombinase activity).
L F, Bancsi, I K, van der Linden, R M, Bertina   +2 more
openaire   +2 more sources

[Antiphospholipid and anti beta 2-glycoprotein I antibodies].

Annales de biologie clinique, 1995
Recent studies have shown that beta 2glycoprotein I (beta 2GPI), a plasma inhibitor of coagulation with affinity for anionic phospholipids, is frequently required for the formation of the epitopes recognized by some anti-phospholipid antibodies.
J, Arvieux, B, Roussel, M G, Colomb
openaire   +2 more sources