Results 291 to 300 of about 267,362 (329)
Some of the next articles are maybe not open access.
Journal of immunology (Baltimore, Md. : 1950), 1998
"Antiphospholipid" autoantibodies are associated with arterial and venous thrombosis, recurrent fetal loss, and thrombocytopenia. At present, the best-characterized antigenic target for these autoantibodies (or Abs) is the phospholipid-binding protein beta2-glycoprotein I (beta2GPI).
Y, Sheng, D A, Kandiah, S A, Krilis
openaire +1 more source
"Antiphospholipid" autoantibodies are associated with arterial and venous thrombosis, recurrent fetal loss, and thrombocytopenia. At present, the best-characterized antigenic target for these autoantibodies (or Abs) is the phospholipid-binding protein beta2-glycoprotein I (beta2GPI).
Y, Sheng, D A, Kandiah, S A, Krilis
openaire +1 more source
The beta-2-glycoprotein I and antiphospholipid antibodies.
Clinical and experimental rheumatology, 1992Beta 2-GPI is a single chain, 50 kd glycoprotein made up of 326 amino-acids, present in human plasma at concentrations of about 200 micrograms/ml. It has been shown to represent the "serum cofactor" important in determining the binding of aCL to phospholipids both in fluid and in solid phase assays.
Y, Shoenfeld, P L, Meroni
openaire +1 more source
Anti-β 2 -Glycoprotein I Autoantibodies and Atherosclerosis
International Reviews of Immunology, 2002beta 2-Glycoprotein I (beta 2-GPI) is a major antigen for antiphospholipid antibodies (aPL) present in patients with antiphospholipid syndrome (APS). We previously reported that beta 2-GPI specifically binds to oxidized low-density lipoprotein (oxLDL).
Eiji, Matsuura +6 more
openaire +2 more sources
British journal of haematology, 1995
Some researchers claim that lupus anticoagulant-positive plasma may cause a false-positive reaction in the test for activated protein C (APC) resistance, a hereditary thrombophilic state characterized by abnormal factor V, which frequently causes venous thrombosis.
J, Matsuda +5 more
openaire +1 more source
Some researchers claim that lupus anticoagulant-positive plasma may cause a false-positive reaction in the test for activated protein C (APC) resistance, a hereditary thrombophilic state characterized by abnormal factor V, which frequently causes venous thrombosis.
J, Matsuda +5 more
openaire +1 more source
Beta-2-glycoprotein-I, infections, antiphospholipid syndrome and therapeutic considerations
Clinical Immunology, 2004Evidence supports the association between infectious agents, antiphospholipid syndrome (APS), and the presence of antiphospholipid antibodies and anti-beta2-glycoprotein-I (beta2GPI) antibodies. Several mechanisms have been proposed to explain the role of bacteria/viruses in induction of an autoimmune condition, such as molecular mimicry between ...
Miri, Blank, Yehuda, Shoenfeld
openaire +2 more sources
Thrombosis and haemostasis, 1995
beta 2 glycoprotein-I (beta 2GPI), a cofactor for antiphospholipid antibody (aPA) binding, binds to many anionic macromolecules including heparin. The nature of this interaction with heparin is not well understood and its effect on the purported biological functions of beta 2GPI is unknown.
T, McNally +4 more
openaire +1 more source
beta 2 glycoprotein-I (beta 2GPI), a cofactor for antiphospholipid antibody (aPA) binding, binds to many anionic macromolecules including heparin. The nature of this interaction with heparin is not well understood and its effect on the purported biological functions of beta 2GPI is unknown.
T, McNally +4 more
openaire +1 more source
Anticardiolipin Antibody and Anti-beta 2 Glycoprotein I Antibody Assays
2013Antiphospholipid syndrome (APS) is an autoimmune disease and is a risk factor for a number of clinical manifestations; the classic presentations include fetal death or thrombosis (arterial or venous thromboembolism), in the presence of persistently increased titers of antiphospholipid (aPL) antibodies.
Anne, Raby +2 more
openaire +2 more sources
Beta 2-glycoprotein I--a Bi-Allelic polymorphism.
Acta anthropogenetica, 1981Population samples from Hungary and India have been typed for beta 2-glycoprotein I concentrations. Whereas the Hungarian sample is in fairly good accord with the genetic model set up by Cleve2-beta 2-glycoprotein I concentrations are controlled by two autosomal codominant alleles BgN and BgD-the Indian samples do not fit this model.
H, Walter +7 more
openaire +1 more source
[Hokkaido igaku zasshi] The Hokkaido journal of medical science, 2000
Apoptosis (programmed cell death) is accompanied by loss of phospholipid asymmetry, i.e., translocation of aminophospholipids such as phosphatidylserine to the outer leaflet of the plasma membranes, which results in recognition of these cells by macrophages.
openaire +1 more source
Apoptosis (programmed cell death) is accompanied by loss of phospholipid asymmetry, i.e., translocation of aminophospholipids such as phosphatidylserine to the outer leaflet of the plasma membranes, which results in recognition of these cells by macrophages.
openaire +1 more source
Antibodies to beta(2)-glycoprotein I in ischemic stroke.
Cerebrovascular diseases (Basel, Switzerland), 2000Antibodies to beta(2)-glycoprotein (beta(2)-GPI) have been associated with recurrent thrombotic events in patients with systemic lupus erythematosus. The present study investigated the prevalence of antibodies to beta(2)-GPI in an unselected group of patients with ischemic stroke.
Fiallo P +3 more
openaire +2 more sources