Results 61 to 70 of about 199,951 (284)

Anti-beta 2-glycoprotein I antibodies in a patient with catastrophic antphospholipid syndrome. [PDF]

open access: yes, 1995
IF: 0,559 Autoimmune antiphospholipid antibodies are a hallmark of patients with antiphospholipid syndrome, and require a protein cofactor, beta 2-glycoprotein I, to bind anionic phospholipids. In these same patients, moreover, IgG directly binding beta
PENGO, VITTORIO   +3 more
core  

Anti-beta 2-glycoprotein I antibodies: a marker of antiphospholipid syndrome? [PDF]

open access: yes, 1995
Anticardiolipin (aCL) and anti-beta(2)-glycoprotein I(anti beta 2GPI) antibodies have been shown in animal models as not cross-reacting antibody populations.
A. Tincani   +8 more
core   +1 more source

Investigating the Antiviral Properties of Nyctanthes arbor-tristis Linn against the Ebola, SARS-CoV-2, Nipah, and Chikungunya Viruses: A Computational Simulation Study

open access: yesPharmaceuticals
Background: The hunt for naturally occurring antiviral compounds to combat viral infection was expedited when COVID-19 and Ebola spread rapidly. Phytochemicals from Nyctanthes arbor-tristis Linn were evaluated as significant inhibitors of these viruses ...
Raed Albiheyri   +4 more
doaj   +1 more source

3005 Integrin Mac-1 Potentiates Neutrophil Adhesion and NET Release in Antiphospholipid Syndrome

open access: yesJournal of Clinical and Translational Science, 2019
OBJECTIVES/SPECIFIC AIMS: While the role of antiphospholipid antibodies in activating endothelial cells has been extensively studied, the impact of these antibodies on the adhesive potential of leukocytes has received considerably less attention.
Gautam Sule   +4 more
doaj   +1 more source

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab   +19 more
wiley   +1 more source

Diagnosis of antiphospholipid syndrome in routine clinical practice. [PDF]

open access: yes, 2013
The updated international consensus criteria for definite antiphospholipid syndrome (APS) are useful for scientific clinical studies. However, there remains a need for diagnostic criteria for routine clinical use.
Hills, J   +3 more
core  

Conformationally altered beta(2)-glycoprotein I is the antigen for anti-cardiolipin autoantibodies [PDF]

open access: yes, 1999
Anti-cardiolipin autoantibodies (aCL) induce thrombosis and recurrent fetal death. These antibodies require a 'cofactor', identified as beta(2)-glycoprotein I (beta(2)-GPI), to bind phospholipids. We show here that aCL can bind beta(2)-GPI in the absence
Johnson, P.M.   +4 more
core   +1 more source

Cross-reactivity between annexin A2 and Beta-2-glycoprotein I in animal models of antiphospholipid syndrome [PDF]

open access: yes, 2020
Antiphospholipid syndrome (APS) affects coagulation and the brain by autoimmune mechanisms. The major antigen in APS is beta-2-glycoprotein I (?2-GPI) is known to complex with annexin A2 (ANXA2), and antibodies to ANXA2 have been described in APS.
Weiss R.   +7 more
core   +1 more source

A Polymerase-chain-reaction Assay for the Specific Identification of Transcripts Encoded by Individual Carcinoembryonic Antigen (CEA)-gene-family Members [PDF]

open access: yes, 1993
Carcinoembryonic antigen (CEA) is a tumor marker that belongs to a family of closely related molecules with variable expression patterns. We have developed sets of oligonucleotide primers for the specific amplification of transcripts from individual CEA ...
Zimmermann, Wolfgang   +15 more
core   +1 more source

Clinical and laboratory characteristics of Brazilian versus non-Brazilian primary antiphospholipid syndrome patients in AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) clinical database and repository

open access: yesAdvances in Rheumatology, 2021
Background Antiphospholipid syndrome (APS) is characterized by episodes of thrombosis, obstetric morbidity or both, associated with persistently positive antiphospholipid antibodies (aPL).
Erivelton de Azevedo Lopes   +25 more
doaj   +1 more source

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