Dimers of β2-Glycoprotein I Mimic thein Vitro Effects of β2-Glycoprotein I-Anti-β2-glycoprotein I Antibody Complexes [PDF]
Anti-beta(2)-glycoprotein I antibodies are thought to cause lupus anticoagulant activity by forming bivalent complexes with beta(2)-glycoprotein I (beta(2)GPI). To test this hypothesis, chimeric fusion proteins were constructed of the dimerization domain (apple 4) of factor XI and beta(2)GPI.
Lutters, B. C. +4 more
openaire +3 more sources
Budd-Chiari Syndrome as an Initial Presentation of Antiphospholipid Syndrome in a Male [PDF]
In Budd-Chiari Syndrome (BCS) there is narrowing and obstruction of the veins of the hepatic veins. Patients have upper quadrant abdominal pain, hepatomegaly and/or ascites.
Pusala Varun Narayana +3 more
doaj +1 more source
Morphology, biophysical properties and protein-mediated fusion of archaeosomes. [PDF]
As variance from standard phospholipids of eubacteria and eukaryotes, archaebacterial diether phospholipids contain branched alcohol chains (phytanol) linked to glycerol exclusively with ether bonds.
Vid Šuštar +7 more
doaj +1 more source
Thrombosis and antiphospholipid antibodies in Japanese COVID-19: based on propensity score matching
BackgroundThrombosis is a unique complication of coronavirus disease 2019 (COVID-19). Although antiphospholipid antibodies (aPL) are detected in COVID-19 patients, their clinical significance remains elusive.
Seiya Oba +18 more
doaj +1 more source
beta 2-Glycoprotein I: a plasma inhibitor of the contact activation of the intrinsic blood coagulation pathway. [PDF]
I. Schousboe
semanticscholar +2 more sources
Orthobunyavirus ultrastructure and the curious tripodal glycoprotein spike [PDF]
The genus <i>Orthobunyavirus</i> within the family <i>Bunyaviridae</i> constitutes an expanding group of emerging viruses, which threaten human and animal health.
McLees, A. +42 more
core +1 more source
Gram Negative Bacterial Inflammation Ameliorated by the Plasma Protein Beta 2-Glycoprotein I. [PDF]
Zhou S +11 more
europepmc +3 more sources
A Study of Anti Beta-2 Glycoprotein I and Anti-Prothrombin Antibodies in Patients with Unexplained Recurrent Pregnancy Losses. [PDF]
Singh A, Nangia A, Sharma S, Puri M.
europepmc +3 more sources
Antiphospholipid Antibodies and Antiphospholipid Syndrome During Pregnancy: Diagnostic Concepts
Antiphospholipid syndrome comprises of a wide spectrum of clinical and obstetric manifestations linked to the presence of antiphospholipid antibodies. APS was described in the context of lupus and later as an isolated syndrome or primary APS.
Roger A Levy +3 more
doaj +1 more source
Correction of the iron overload defect in beta-2-microglobulin knockout mice by lactoferrin abolishes their increased susceptibility to tuberculosis. [PDF]
As a resident of early endosomal phagosomes, Mycobacterium tuberculosis is connected to the iron uptake system of the host macrophage. beta-2-microglobulin (beta2m) knockout (KO) mice are more susceptible to tuberculosis than wild-type mice, which is ...
Friedrich Priem +11 more
core +1 more source

