Results 31 to 40 of about 267,362 (329)

Prevalence of lupus anticoagulant in patients with cirrhosis: relationship with beta-2-glycoprotein I plasma levels

Journal of Hepatology, 1994
We have previously demonstrated that patients with cirrhosis may be positive for lupus anticoagulant and anticardiolipin antibodies. The prevalence and clinical value of antiphospholipid antibodies in cirrhosis have never been described.
C Quintarelli, Domenico Ferro, Guido Valesini   +2 more
exaly   +2 more sources

Lupus anticoagulant activity of autoimmune antiphospholipid antibodies is dependent upon beta 2-glycoprotein I. [PDF]

, 1992
It has been reported that antiphospholipid autoantibodies do not recognize phospholipid alone, but rather the plasma protein beta 2-glycoprotein I (beta 2GPI), or a beta 2GPI-phospholipid complex.
Winfield, John B., R A Roubey, Buyon, Jill P., J B Winfield, J P Buyon, C W Pratt, Roubey, Robert A.S., Pratt, Charlotte W.   +7 more
core   +3 more sources

Correlation between beta-2-glycoprotein I gene polymorphism and anti-beta-2 glycoprotein I antibodies in patients with multibacillary leprosy

Archives of Dermatological Research, 2010
Antiphospholipid antibodies, such as anti-beta 2-glycoprotein I (beta 2GPI), are present in multibacillary leprosy (MB) patients; however, MB patients do not usually present with antiphospholipid antibody syndrome (APS), which is characterized by ...
Ana Maria Roselino, José Fernando C. Figueiredo, Celso Teixeira Mendes-Junior, Maria José Franco Brochado, BROCHADO, Maria Jose Franco, MENDES-JUNIOR, Celso Teixeira, ROSELINO, Ana Maria, LOUZADA-JUNIOR, Paulo, Paulo Louzada-Junior, Olivia Makiyama Kim, KIM, Olivia Makiyama, FIGUEIREDO, Jose Fernando C.   +11 more
core   +3 more sources

Studies on specific interaction of beta-2-glycoprotein I with HBsAg

World Journal of Gastroenterology, 2003
To observe the binding activity of beta-2-glycoprotein I(beta(2)GPI) to hepatitis B surface antigen (HBsAg) and the possible roles of beta(2)GPI in hepatitis B virus (HBV) infection.The rationale of ELISA methods and ELISA-based research method and ligand-blotting technique were used to detect the specific interaction of beta(2)GPI with HBsAg.With the ...
Pu-Jun, Gao, Yun-Feng, Piao, Xiao-Dong, Liu, Li-Ke, Qu, Yang, Shi, Xiao-Cong, Wang, Han-Yi, Yang   +6 more
openaire   +4 more sources

Prevalence of beta 2-glycoprotein I antibody in systemic lupus erythematosus patients with beta 2-glycoprotein I dependent antiphospholipid antibodies. [PDF]

Annals of the Rheumatic Diseases, 1995
To investigate whether beta 2-glycoprotein I antibody (aGPI) exists in sera that are positive for antiphospholipid antibodies (aPL).Thirty six patients with systemic lupus erythematosus (SLE) and 20 healthy volunteers were recruited. GPI independent and dependent aPL (anticardiolipin (aCL), antiphosphatidylserine, antiphosphatidylinositol ...
J, Matsuda, N, Saitoh, M, Gotoh, K, Gohchi, M, Tsukamoto   +4 more
openaire   +4 more sources

beta(2)-Glycoprotein I: a novel component of innate immunity

, 2011
Sepsis is a systemic host response to invasive infection by bacteria. Despite treatment with antibiotics, current mortality rates are in the range of 20%-25%, which makes sepsis the most important cause of death in intensive care.
Stephanie D. D. C. Monk, de Laat, Bas, Urbanus, Rolf T., Bas de Laat, Meijers, Joost C. M., Matthias Mörgelin, Johannes H. M. Levels, de Groot, Philip G., Mörgelin, Matthias, Joost C. M. Meijers, Agar, Cetin, Rolf T. Urbanus, Herwald, Heiko,, van Os, Gwendolyn M. A., Monk, Stephanie D. D. C., Philip G. de Groot, Tom van der Poll, Mörgelin, Matthias,, Çetin Ağar, Gwendolyn van Os, van Os, Gwendolyn, van der Poll, Tom, Levels, Johannes H. M., Lund University., Herwald, Heiko, Heiko Herwald   +25 more
core   +2 more sources

Microheterogeneity of beta-2 glycoprotein I: implications for binding to anionic phospholipids [PDF]

Biochemical Journal, 1999
Considerable interest is currently focused on the interactions of beta-2 glycoprotein I (β2GPI) and anti-phospholipid antibodies with anionic phospholipids in an attempt to understand the association between these antibodies and clinical diseases such as thrombosis.
T A, Brighton, Y P, Dai, P J, Hogg, C N, Chesterman   +3 more
openaire   +4 more sources

Cross-reactivity between annexin A2 and Beta-2-glycoprotein I in animal models of antiphospholipid syndrome

, 2020
Antiphospholipid syndrome (APS) affects coagulation and the brain by autoimmune mechanisms. The major antigen in APS is beta-2-glycoprotein I (?2-GPI) is known to complex with annexin A2 (ANXA2), and antibodies to ANXA2 have been described in APS.
Weiss R., Arango M.T., Bitton A., Shoenfeld Y., Chapman J., Nahary L., Benhar I., Blank M.   +7 more
core   +3 more sources

Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: beta 2-glycoprotein I (apolipoprotein H).

Proceedings of the National Academy of Sciences of the United States of America, 1990
H. McNeil, R. Simpson, C. Chesterman, S. Krilis   +3 more
semanticscholar   +2 more sources

Beta-2-glycoprotein I as a biomarker for sepsis in critically ill patients in the intensive care unit: a prospective cohort study [PDF]

Critical Care, 2020
Irene T. Schrijver, Hans Kemperman, Mark Roest, Jozef Kesecioglu, Dylan W. de Lange   +4 more
doaj   +2 more sources