Results 31 to 40 of about 42,428,678 (264)

Dimers of β2-Glycoprotein I Mimic thein Vitro Effects of β2-Glycoprotein I-Anti-β2-glycoprotein I Antibody Complexes [PDF]

Journal of Biological Chemistry, 2001
Anti-beta(2)-glycoprotein I antibodies are thought to cause lupus anticoagulant activity by forming bivalent complexes with beta(2)-glycoprotein I (beta(2)GPI). To test this hypothesis, chimeric fusion proteins were constructed of the dimerization domain (apple 4) of factor XI and beta(2)GPI.
Lutters, B. C., Meijers, J. C., Derksen, R. H., Arnout, J., de Groot, P. G.   +4 more
openaire   +3 more sources

Thrombosis and antiphospholipid antibodies in Japanese COVID-19: based on propensity score matching

Frontiers in Immunology, 2023
BackgroundThrombosis is a unique complication of coronavirus disease 2019 (COVID-19). Although antiphospholipid antibodies (aPL) are detected in COVID-19 patients, their clinical significance remains elusive.
Seiya Oba, Tadashi Hosoya, Risa Kaneshige, Daisuke Kawata, Taiki Yamaguchi, Takahiro Mitsumura, Takahiro Mitsumura, Sho Shimada, Sho Shibata, Tomoya Tateishi, Ryuji Koike, Shuji Tohda, Akihiro Hirakawa, Nukui Yoko, Nukui Yoko, Yasuhiro Otomo, Junzo Nojima, Yasunari Miyazaki, Shinsuke Yasuda   +18 more
doaj   +1 more source

Budd-Chiari Syndrome as an Initial Presentation of Antiphospholipid Syndrome in a Male [PDF]

Journal of Clinical and Diagnostic Research, 2022
In Budd-Chiari Syndrome (BCS) there is narrowing and obstruction of the veins of the hepatic veins. Patients have upper quadrant abdominal pain, hepatomegaly and/or ascites.
Pusala Varun Narayana, Prasanna Kumar Satpathy, S Bharath Gowda, Srivatsav Addepalli   +3 more
doaj   +1 more source

Morphology, biophysical properties and protein-mediated fusion of archaeosomes. [PDF]

PLoS ONE, 2012
As variance from standard phospholipids of eubacteria and eukaryotes, archaebacterial diether phospholipids contain branched alcohol chains (phytanol) linked to glycerol exclusively with ether bonds.
Vid Šuštar, Jasna Zelko, Patrizia Lopalco, Simona Lobasso, Ajda Ota, Nataša Poklar Ulrih, Angela Corcelli, Veronika Kralj-Iglič   +7 more
doaj   +1 more source

Complete nucleotide and deduced amino acid sequence of human beta 2-glycoprotein I [PDF]

, 1991
The nucleotide and complete amino acid sequence for the human ß2-glycoprotein I (ß,I) was derived by sequencing the cDNA clone pB2I- 1. In addition to the 326 amino acid residues of the mature protein this clone codes for a putative leader peptide and ...
Estaller, C., Estaller, C, Steinkasserer, Alexander, T Robert B. Sim, Steinkasserer, A, Day, Anthony J., Er Steinkasserer, Sim, Robert B., T Cornelia Estaller, Day, AJ; id_orcid, Weiss, Elisabeth H., Sim, RB, T Elisabeth H. Weiss, Weiss, EH, Anthony J. Day   +14 more
core   +1 more source

Orthobunyavirus ultrastructure and the curious tripodal glycoprotein spike [PDF]

, 2013
The genus <i>Orthobunyavirus</i> within the family <i>Bunyaviridae</i> constitutes an expanding group of emerging viruses, which threaten human and animal health.
McLees, A., Huiskonen, JT, Yeromonahos, C, Christelle Yeromonahos (413081), Juha T. Huiskonen (191734), David Bitto, David Bitto (413079), Bowden, Thomas A, Elliott, RM, Elliott, Richard M., Richard M. Elliott (252934), Elliott, Richard, Bowden Thomas A., McLees, A, Yeromonahos, Christelle, Huiskonen, Juha T., Angela McLees (413080), Elliott, Richard M, Christelle Yeromonahos, Pierson, Ted, Huiskonen, J.T., Elliott, R.M., Huiskonen, Juha, Richard M Elliott, McLees, Angela, Bowden, T.A., Bitto, David, Bitto David, Bitto, D, Huiskonen, Juha T, Elliott Richard M., Bowden, Thomas A., Thomas A. Bowden (413078), McLees Angela, Bitto, D., Bowden, Thomas, Huiskonen Juha T., Angela McLees, Bowden, TA, Yeromonahos, C., Thomas A Bowden, Yeromonahos Christelle, Juha T Huiskonen   +42 more
core   +1 more source

Prevalence of beta 2-glycoprotein I antibody in systemic lupus erythematosus patients with beta 2-glycoprotein I dependent antiphospholipid antibodies. [PDF]

Annals of the Rheumatic Diseases, 1995
To investigate whether beta 2-glycoprotein I antibody (aGPI) exists in sera that are positive for antiphospholipid antibodies (aPL).Thirty six patients with systemic lupus erythematosus (SLE) and 20 healthy volunteers were recruited. GPI independent and dependent aPL (anticardiolipin (aCL), antiphosphatidylserine, antiphosphatidylinositol ...
J, Matsuda, N, Saitoh, M, Gotoh, K, Gohchi, M, Tsukamoto   +4 more
openaire   +2 more sources

Antiphospholipid Antibodies and Antiphospholipid Syndrome During Pregnancy: Diagnostic Concepts

Frontiers in Immunology, 2015
Antiphospholipid syndrome comprises of a wide spectrum of clinical and obstetric manifestations linked to the presence of antiphospholipid antibodies. APS was described in the context of lupus and later as an isolated syndrome or primary APS.
Roger A Levy, Flavia eCunha, Guilherme R de Jesús, Nilson R de Jesús   +3 more
doaj   +1 more source

Correction of the iron overload defect in beta-2-microglobulin knockout mice by lactoferrin abolishes their increased susceptibility to tuberculosis. [PDF]

, 2002
As a resident of early endosomal phagosomes, Mycobacterium tuberculosis is connected to the iron uptake system of the host macrophage. beta-2-microglobulin (beta2m) knockout (KO) mice are more susceptible to tuberculosis than wild-type mice, which is ...
Friedrich Priem, Priem, F, Kaufmann, Stefan HE, Collins, Helen L, Ulrich E. Schaible, Kaufmann, S H E, Schaible, Ulrich E, Helen L. Collins, Collins, H L, Priem, Friedrich, Stefan H.E. Kaufmann, Schaible, U E   +11 more
core   +1 more source

Structural analysis of the adenovirus type 2 E3/19K protein using mutagenesis and a panel of conformation-sensitive monoclonal antibodies [PDF]

, 2008
The E3/19K protein of human adenovirus type 2 (Ad2) was the first viral protein shown to interfere with antigen presentation. This 25 kDa transmembrane glycoprotein binds to major histocompatibility complex (MHC) class I molecules in the endoplasmic ...
Menz, Beatrice, Schmid, Ralf, Burgert, Hans-Gerhard, Martina Sester, Hans-Gerhard Burgert, Sester, Martina, Koebernick, Katja, Beatrice Menz, Katja Koebernick, Ralf Schmid   +9 more
core   +1 more source