Results 31 to 40 of about 199,951 (284)

Orthobunyavirus ultrastructure and the curious tripodal glycoprotein spike [PDF]

open access: yes, 2013
The genus <i>Orthobunyavirus</i> within the family <i>Bunyaviridae</i> constitutes an expanding group of emerging viruses, which threaten human and animal health.
McLees, A.   +42 more
core   +1 more source

Prevalence of beta 2-glycoprotein I antibody in systemic lupus erythematosus patients with beta 2-glycoprotein I dependent antiphospholipid antibodies. [PDF]

open access: yesAnnals of the Rheumatic Diseases, 1995
To investigate whether beta 2-glycoprotein I antibody (aGPI) exists in sera that are positive for antiphospholipid antibodies (aPL).Thirty six patients with systemic lupus erythematosus (SLE) and 20 healthy volunteers were recruited. GPI independent and dependent aPL (anticardiolipin (aCL), antiphosphatidylserine, antiphosphatidylinositol ...
J, Matsuda   +4 more
openaire   +2 more sources

Immune responses against domain I of beta 2-glycoprotein I are driven by conformational changes: Domain I of beta 2-glycoprotein I harbors a cryptic immunogenic epitope [PDF]

open access: yes, 2011
Objective The presence of autoantibodies against a cryptic epitope in domain I of beta 2-glycoprotein I (beta 2GPI) is strongly associated with thrombotic events in patients with the antiphospholipid syndrome. We hypothesized that a conformational change
Gebbink, Martijn F.   +13 more
core   +1 more source

Antiphospholipid Antibodies and Antiphospholipid Syndrome During Pregnancy: Diagnostic Concepts

open access: yesFrontiers in Immunology, 2015
Antiphospholipid syndrome comprises of a wide spectrum of clinical and obstetric manifestations linked to the presence of antiphospholipid antibodies. APS was described in the context of lupus and later as an isolated syndrome or primary APS.
Roger A Levy   +3 more
doaj   +1 more source

Correction of the iron overload defect in beta-2-microglobulin knockout mice by lactoferrin abolishes their increased susceptibility to tuberculosis. [PDF]

open access: yes, 2002
As a resident of early endosomal phagosomes, Mycobacterium tuberculosis is connected to the iron uptake system of the host macrophage. beta-2-microglobulin (beta2m) knockout (KO) mice are more susceptible to tuberculosis than wild-type mice, which is ...
Friedrich Priem   +11 more
core   +1 more source

Structural analysis of the adenovirus type 2 E3/19K protein using mutagenesis and a panel of conformation-sensitive monoclonal antibodies [PDF]

open access: yes, 2008
The E3/19K protein of human adenovirus type 2 (Ad2) was the first viral protein shown to interfere with antigen presentation. This 25 kDa transmembrane glycoprotein binds to major histocompatibility complex (MHC) class I molecules in the endoplasmic ...
Menz, Beatrice   +9 more
core   +1 more source

Sequence alignment of the Bugula neritina putative mature glycoprotein hormone beta 5 with homologs. [PDF]

open access: yes, 2016
CgGHB5: (EKC24490.1) glycoprotein hormone beta 5 Crassostrea gigas; TcGHB5: (EFA10760.1glycoprotein hormone beta 5) Tribolium castaneum; TnGHB5: (KRZ59516.1) glycoprotein hormone beta 5 Trichinella nativa; BmGHB5: (NP_001124380.1) glycoprotein hormone ...
Yue Him Wong (176531)   +4 more
core   +1 more source

beta(2)-Glycoprotein I: a novel component of innate immunity [PDF]

open access: yes, 2011
Sepsis is a systemic host response to invasive infection by bacteria. Despite treatment with antibiotics, current mortality rates are in the range of 20%-25%, which makes sepsis the most important cause of death in intensive care.
Stephanie D. D. C. Monk   +25 more
core   +1 more source

Structure-function relationships for the interleukin 2 receptor system

open access: yesMemorias do Instituto Oswaldo Cruz, 1987
Receptors for interleukin 2 (IL-2) esit in at least three forms which differ in their subunit compositio, their affinity for ligand and their ability to mediate a cellular reponse.
Richard J. Robb
doaj   +1 more source

Studies on specific interaction of beta-2-glycoprotein I with HBsAg

open access: yesWorld Journal of Gastroenterology, 2003
To observe the binding activity of beta-2-glycoprotein I(beta(2)GPI) to hepatitis B surface antigen (HBsAg) and the possible roles of beta(2)GPI in hepatitis B virus (HBV) infection.The rationale of ELISA methods and ELISA-based research method and ligand-blotting technique were used to detect the specific interaction of beta(2)GPI with HBsAg.With the ...
Pu-Jun, Gao   +6 more
openaire   +2 more sources

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