Immune Complexes of Beta-2-Glycoprotein I and IgA Antiphospholipid Antibodies Identify Patients With Elevated Risk of Thrombosis and Early Mortality After Heart Transplantation [PDF]
Frontiers in Immunology, 2019 Background: The presence of anti-Beta 2 glycoprotein antibodies (aB2GP1) of IgA isotype is common in patients with functional impairment of the organs in which B2GP1 is elaborated.
Manuel Serrano +9 more
doaj +2 more sources
Renal Transplantation Dramatically Reduces IgA Anti-beta-2-glycoprotein I Antibodies in Patients with Endstage Renal Disease [PDF]
Journal of Immunology Research, 2014 IgA anti-beta-2-glycoprotein I (aB2GPI) antibodies have been related to vascular pathology in the general population and mainly in hemodialyzed patients (prevalence 33%) in whom an elevated incidence of thrombosis and mortality is found. In this paper we
Manuel Serrano +9 more
doaj +2 more sources
Beta-2-glycoprotein I as a biomarker for sepsis in critically ill patients in the intensive care unit: a prospective cohort study [PDF]
Critical Care, 2020 Irene T. Schrijver +4 more
doaj +2 more sources
Anti-beta 2 glycoprotein I antibodies in centenarians [PDF]
Experimental Gerontology, 2004 Non-organ-specific autoantibodies are present in centenarians without evidence of autoimmune diseases but conflicting or no data on anti-phospholipid and anti-phospholipid binding proteins were reported.To investigate the presence and antigen specificity of anti-phospholipid and anti-phospholipid binding proteins in centenarians.Seventy-seven ...
Meroni P. L. +8 more
openaire +5 more sources
Dimers of β2-Glycoprotein I Mimic thein Vitro Effects of β2-Glycoprotein I-Anti-β2-glycoprotein I Antibody Complexes [PDF]
Journal of Biological Chemistry, 2001 Anti-beta(2)-glycoprotein I antibodies are thought to cause lupus anticoagulant activity by forming bivalent complexes with beta(2)-glycoprotein I (beta(2)GPI). To test this hypothesis, chimeric fusion proteins were constructed of the dimerization domain (apple 4) of factor XI and beta(2)GPI.
Lutters, B. C. +4 more
openaire +3 more sources
Budd-Chiari Syndrome as an Initial Presentation of Antiphospholipid Syndrome in a Male [PDF]
Journal of Clinical and Diagnostic Research, 2022 In Budd-Chiari Syndrome (BCS) there is narrowing and obstruction of the veins of the hepatic veins. Patients have upper quadrant abdominal pain, hepatomegaly and/or ascites.
Pusala Varun Narayana +3 more
doaj +1 more source
Paradoxical association between the 316 Trp to Ser beta 2-glycoprotein I (Beta2GPI) polymorphism and anti-Beta2GPI antibodies [PDF]
, 2003 We report a woman with an obstetric history ofa stillbirth at 28 weeks, associated with hypertension and severe intrauterine growth restriction and a miscarriage at 9 weeks.
Machin, S.J. +5 more
core +1 more source
Complete nucleotide and deduced amino acid sequence of human beta 2-glycoprotein I [PDF]
, 1991 The nucleotide and complete amino acid sequence for the human ß2-glycoprotein I (ß,I) was derived by sequencing the cDNA clone pB2I- 1. In addition to the 326 amino acid residues of the mature protein this clone codes for a putative leader peptide and ...
Estaller, C. +14 more
core +1 more source
Thrombosis and antiphospholipid antibodies in Japanese COVID-19: based on propensity score matching
Frontiers in Immunology, 2023 BackgroundThrombosis is a unique complication of coronavirus disease 2019 (COVID-19). Although antiphospholipid antibodies (aPL) are detected in COVID-19 patients, their clinical significance remains elusive.
Seiya Oba +18 more
doaj +1 more source
Morphology, biophysical properties and protein-mediated fusion of archaeosomes. [PDF]
PLoS ONE, 2012 As variance from standard phospholipids of eubacteria and eukaryotes, archaebacterial diether phospholipids contain branched alcohol chains (phytanol) linked to glycerol exclusively with ether bonds.
Vid Šuštar +7 more
doaj +1 more source