Results 151 to 160 of about 24,774 (261)

Inflammation and Cancer: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Chronic inflammation fuels tumorigenesis via “internal drivers” and “external attractions.” Targeting these core mechanisms with combined therapies/novel deliveries enables precise, potent anti‐inflammatory–antitumor treatment. ABSTRACT Inflammation is a core pathological factor regulating tumor initiation, progression, and therapeutic resistance, and ...
Xiaodie Liu, Ziyuan Wang, Huirong Zhu, Yicun Han, Qing Ji   +4 more
wiley   +1 more source

Oligodeoxynucleotides antisense to mRNA encoding protein kinase A, protein kinase C, and beta-adrenergic receptor kinase reveal distinctive cell-type-specific roles in agonist-induced desensitization.

, 1994
Meng-Fu Maxwell Shih, C C Malbon
openalex   +2 more sources

Therapeutic Potential of the β3-Adrenergic Receptor and Its Ligands in Cardiovascular Diseases. [PDF]

Int J Mol Sci
Kempiński M, Jańczak P, Porębska A, Zawadzka PS, Jastrzębska P, Granat MM, Wojciechowska M.   +6 more
europepmc   +1 more source

Deceptive beauty of non‐natural structures

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Structures of proteins and multiprotein complexes are considered landmark achievements. However, in many cases, mutant proteins are used for structural work. Even when wild type proteins are used, crystallization or complex formation for cryoEM is performed in highly nonphysiological conditions.
Vsevolod V. Gurevich, Eugenia V. Gurevich   +1 more
wiley   +1 more source

Vitamin A Derivatives and Adipose Tissue Differentiation: Molecular Pathways Driving Browning and Anti-Obesity Effects. [PDF]

Curr Obes Rep
Bilikozen Aygun B, Basturk B, Ayaz A.
europepmc   +1 more source

Acaricidal activity of small molecule antagonists of the tick kinin receptor against Rhipicephalus microplus acaricide‐susceptible and resistant strains

Pest Management Science, Volume 82, Issue 2, Page 1618-1628, February 2026.
Two small molecules, SACC‐0039590 and SACC‐0428788, killed cattle fever tick, R. microplus, susceptible Deutch strain and pyrethroid resistant Arauquita strain larvae. SACC‐0039590 at 1 mM decreased the reproductive parameters of Deutch females. Abstract BACKGROUND Resistance to acaricides underscores the need for tick control alternatives.
Waleed M. Arafa, Kimberly H. Lohmeyer, Patricia V. Pietrantonio   +2 more
wiley   +1 more source

Chronic β-Blockade and Systemic Homeostasis: Molecular Integration of Cardiorenal and Immune Pathways, a Narrative Review. [PDF]

Biomolecules
Park J, Hamanaka A, Park I, Abdelhady HG.   +3 more
europepmc   +1 more source

Regulation of adrenergic receptor function by phosphorylation. II. Effects of agonist occupancy on phosphorylation of alpha 1- and beta 2-adrenergic receptors by protein kinase C and the cyclic AMP-dependent protein kinase.

, 1987
Michel Bouvier, L.M. Fredrik Leeb-Lundberg, Jeffrey Benovic, Marc G. Caron, Robert J. Lefkowitz   +4 more
openalex   +1 more source

Heart matters: How glucose‐ and lipid‐modulating drugs remodel epicardial adipose tissue accumulation, inflammatory patterns and browning

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 878-894, February 2026.
Abstract Epicardial adipose tissue (EAT) is a metabolically active visceral fat depot located between the myocardium and the visceral pericardium, exerting direct paracrine and vasocrine effects on the heart and coronary vessels. Under physiological conditions, EAT supports myocardial energy metabolism and thermoregulation through fatty acid supply and
Elisabeth Heuboeck, Charnkamal Singh Bhogal, Markus Mandl   +2 more
wiley   +1 more source