Results 191 to 200 of about 26,478 (271)
Targeted Therapies in Infantile Hemangiomas and Vascular Malformations: From β-Blockers to PI3K/AKT/mTOR Inhibitors. [PDF]
Arasiewicz H, Dec M.
europepmc +1 more source
Abstract Catecholamines are classically viewed as neuronal transmitters and adrenal hormones; however, accumulating evidence demonstrates that sources other than nerve fibres and adrenal medulla play a fundamental role in local organ regulation. Physiological paradoxes, such as preserved organ function after denervation or transplantation, challenge a ...
Mariana G. de Oliveira +3 more
wiley +1 more source
Catecholamines Activate a Tumour Progression Program in Differentiated Tumour Hepatocytes
ABSTRACT Background and Aims The sympathetic nervous system is involved in the progression and aggressiveness of several cancers, including hepatocellular carcinoma (HCC). However, the specific effects of sympathetic innervation and catecholamines on tumour hepatocyte behaviour remain poorly understood.
Elise Lelou +14 more
wiley +1 more source
Comparative anatomy and metabolic profiles of brown and white adipose tissue in humans. [PDF]
Villarreal J, Baranova A.
europepmc +1 more source
Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar +4 more
wiley +1 more source
Abstract figure legend The β1‐adrenergic receptor is the predominant adrenergic subtype expressed on cardiac myocytes. Upon stimulation it activates downstream signalling pathways that increase the heart rate and cardiac output to meet metabolic demands.
Parham Diba +13 more
wiley +1 more source
Effect of premorbid beta-blockers on cardiac function and clinical outcomes in septic patients: a retrospective study. [PDF]
Yang S, Feng R, Fang X, Wei C.
europepmc +1 more source
CaV1.2 dynamics in native male arterial myocytes
Abstract figure legend Proposed model of microtubule‐dependent CaV1.2 reorganization in vascular disease. Schematic illustration of microtubule‐mediated delivery and stabilization of CaV1.2 channels into enlarged plasma membrane clusters in response to Ang II or hyperglycaemia, promoting cooperative gating and enhanced Ca2+ influx. Abstract L‐type CaV1.
Miguel Martin‐Aragon Baudel +9 more
wiley +1 more source
Vasospasm-Induced Takotsubo Cardiomyopathy: An Underrecognized Phenotype of Ischemia With Nonobstructive Coronary Arteries. [PDF]
Kim AY, Bradel L, Hossain N.
europepmc +1 more source

