Results 191 to 200 of about 26,478 (271)

Endothelium‐ and epithelium‐derived novel endogenous catecholamines as modulators of the autonomic nervous system

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 15, Page 4091-4110, August 2026.
Abstract Catecholamines are classically viewed as neuronal transmitters and adrenal hormones; however, accumulating evidence demonstrates that sources other than nerve fibres and adrenal medulla play a fundamental role in local organ regulation. Physiological paradoxes, such as preserved organ function after denervation or transplantation, challenge a ...
Mariana G. de Oliveira   +3 more
wiley   +1 more source

Catecholamines Activate a Tumour Progression Program in Differentiated Tumour Hepatocytes

open access: yesLiver International, Volume 46, Issue 8, August 2026.
ABSTRACT Background and Aims The sympathetic nervous system is involved in the progression and aggressiveness of several cancers, including hepatocellular carcinoma (HCC). However, the specific effects of sympathetic innervation and catecholamines on tumour hepatocyte behaviour remain poorly understood.
Elise Lelou   +14 more
wiley   +1 more source

Might modulation of the endocannabinoid system provide a potential dual therapeutic strategy for osteoporosis and depression?

open access: yes
General Psychiatry, Volume 39, Issue 4, August 2026.
Peng Wei   +6 more
wiley   +1 more source

Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases

open access: yesObesity Reviews, Volume 27, Issue 8, August 2026.
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar   +4 more
wiley   +1 more source

Pancreatic cancer cachexia promotes cardiac dysfunction through altered adrenergic signalling in the heart

open access: yesThe Journal of Physiology, Volume 604, Issue 15, Page 6281-6301, 1 August 2026.
Abstract figure legend The β1‐adrenergic receptor is the predominant adrenergic subtype expressed on cardiac myocytes. Upon stimulation it activates downstream signalling pathways that increase the heart rate and cardiac output to meet metabolic demands.
Parham Diba   +13 more
wiley   +1 more source

CaV1.2 dynamics in native male arterial myocytes

open access: yesThe Journal of Physiology, Volume 604, Issue 15, Page 6302-6323, 1 August 2026.
Abstract figure legend Proposed model of microtubule‐dependent CaV1.2 reorganization in vascular disease. Schematic illustration of microtubule‐mediated delivery and stabilization of CaV1.2 channels into enlarged plasma membrane clusters in response to Ang II or hyperglycaemia, promoting cooperative gating and enhanced Ca2+ influx. Abstract L‐type CaV1.
Miguel Martin‐Aragon Baudel   +9 more
wiley   +1 more source

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