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European journal of clinical nutrition, 1996 Beta-carotene has been shown to exhibit a good radical-trapping antioxidant activity in vitro. We were interested to see if dietary beta-carotene in combination with various intake levels for vitamin A would also inhibit lipid peroxidation.Sixty male Wistar rats received vitamin A (as retinyl palmitate) for 14 weeks in the diet (40,000, 4000 and 400 IU/
Bast, A. +3 more
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Toxicology, 1985
The safety of beta-carotene, a widely distributed food colorant was assessed in tests with cells and in sub-chronic and chronic experiments with animals. Mutagenicity evaluations which included the standard Ames test and the micro-nucleus test of bone marrow cells from mice showed that beta-carotene exerted no mutagenic properties.
R, Heywood +3 more
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The safety of beta-carotene, a widely distributed food colorant was assessed in tests with cells and in sub-chronic and chronic experiments with animals. Mutagenicity evaluations which included the standard Ames test and the micro-nucleus test of bone marrow cells from mice showed that beta-carotene exerted no mutagenic properties.
R, Heywood +3 more
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2001
Considered to be an effective antioxidant, beta-carotene, a carotenoid that occurs naturally in many vegetables and fruits and that converts to vitamin A in the body, has been the subject of intensive cancer prevention research for decades,1; and is a commonly found supplement on the shelves of most supermarkets.
P, Greenwald, S S, McDonald
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Considered to be an effective antioxidant, beta-carotene, a carotenoid that occurs naturally in many vegetables and fruits and that converts to vitamin A in the body, has been the subject of intensive cancer prevention research for decades,1; and is a commonly found supplement on the shelves of most supermarkets.
P, Greenwald, S S, McDonald
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Bioavailability of beta-carotene in humans
The American Journal of Clinical Nutrition, 1988Normal healthy volunteers were studied after they ingested various beta-carotene doses. Daily administration of 15 or 45 mg beta-carotene resulted in significant increase in plasma beta-carotene levels. The extent of increase and the pattern of plasma beta-carotene levels showed substantial interindividual variation.
N V, Dimitrov +7 more
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Beta‐Carotene in HIV Infectiona
Annals of the New York Academy of Sciences, 1993beta-Carotene has been reported to have an immunostimulatory effect. Recent studies suggest that beta-carotene supplementation can increase CD4 counts in HIV-infected patients. Our double-blind, placebo-controlled clinical trial was designed to test the efficacy of beta-carotene in raising CD4 counts in HIV-infected patients.
G O, Coodley +3 more
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Beta Carotene in Congenital Porphyria
Archives of Dermatology, 1979To the Editor.— In answer to Dr G. S. Stretcher's request for information on the use of beta carotene in congenital porphyria (Archives114:1242-1243, 1978), I would like to bring to his attention two reports of the use of beta carotene in this disease.
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Beta Carotene in Congenital Porphyria
Archives of Dermatology, 1978To the Editor.— Dr George Stretcher, in his article on erythropoietic porphyria, which appeared in the NovemberArchives(113:1553-1557,1977), makes a reference to the lack of information about the long-term treatment with beta carotene. In 1973,I described a young woman, aged 18, with congenital porphyria at the Royal Society of Medicine ( Proc R Soc ...
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Medical Hypotheses, 1997
An hypothesis is presented that is opposed to the conventional viewpoint that beta-carotene is an in vivo free-radical scavenger. It is suggested that there are biochemical reasons why beta-carotene, other carotenoids, and especially their metabolites may be harmful to mammalian systems.
D V, Crabtree, A J, Adler
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An hypothesis is presented that is opposed to the conventional viewpoint that beta-carotene is an in vivo free-radical scavenger. It is suggested that there are biochemical reasons why beta-carotene, other carotenoids, and especially their metabolites may be harmful to mammalian systems.
D V, Crabtree, A J, Adler
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