Results 151 to 160 of about 8,645,876 (363)

A matrix variate inverse Lomax distribution

open access: yesSpecial Matrices
This study presents the matrix variate inverse Lomax distribution as a generalization of the univariate inverse Lomax distribution and shows that this distribution can be derived by using matrix variate gamma distributions.
Nagar Daya K.   +2 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

The distribution of ideals whose norm divides n in the Gaussian ring

open access: yesAIMS Mathematics
Let $ O_{K} = \mathbb{Z}[i] $. For each positive integer $ n $, denote $ \xi_{K}(n) $ as the number of integral ideals whose norm divides $ n $ in $ O_{K} $.
Tong Wei
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Quantitative Methods for Evaluating Long-Term Career Attitudes of the Subjects of Modern Society («Model of the Life Trajectory»)

open access: yesУправленческое консультирование
The article is devoted to the problems of ideas of the subjects of modern society about the long-term prospects for the development of their life path (the so-called “life trajectories”).
P. V. Konyukhovsky, A. V. Yakovleva
doaj   +1 more source

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