Results 61 to 70 of about 275,974 (250)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Different facets of alpha and beta diversity of benthic diatoms along stream watercourse in a large near‐natural catchment

open access: yesEcology and Evolution
Understanding the processes and mechanisms that shape the distribution patterns and variations of biodiversity along spatial gradients continues to be a priority for ecological research. We focused on the biodiversity of benthic diatom communities within
Naicheng Wu   +10 more
doaj   +1 more source

Additive partitioning of a beta diversity index is controversial [PDF]

open access: yesProceedings of the National Academy of Sciences, 2015
A recent study (1) reports the spatial clustering patterns of the global distribution of human infectious diseases. However, there are some controversial issues that arise from the beta diversity partitioning method used in the paper. To further debate these issues, we follow the same notations in the paper (1) by writing the Sorensen beta diversity ...
Youhua, Chen, Dénes, Schmera
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Effect of Disturbance Regime on Alpha and Beta Diversity of Rock Pools

open access: yesDiversity, 2013
Measures of alpha diversity are more frequently used to detect environmental changes and subsequent impacts on biodiversity, while measures based on variability (beta diversity) are said to be more appropriate for detecting those impacts. Theory predicts
Annie Séguin   +2 more
doaj   +1 more source

Disentangling the beta-diversity in anuran parasite communities

open access: yesParasitology, 2020
AbstractThere is great heterogeneity in parasite communities among hosts, understanding the nature and drivers of such variations is still a great scientific quest. Here, we analyse the variation in parasite communities by addressing the following questions: (i) What is the beta-diversity component (nestedness or turnover) that most contributes to beta
Elvira D'Bastiani, Karla M. Campião
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

How does invasion degree shape alpha and beta diversity of freshwater fish at a regional scale?

open access: yesEcology and Evolution, 2022
Freshwater ecosystems appear more vulnerable to biodiversity loss due to several anthropogenic disturbances and freshwater fish are particularly vulnerable to these impacts.
Anna Gavioli   +5 more
doaj   +1 more source

An attribute‐diversity approach to functional diversity, functional beta diversity, and related (dis)similarity measures [PDF]

open access: yesEcological Monographs, 2019
AbstractBased on the framework of attribute diversity (a generalization of Hill numbers of order q), we develop a class of functional diversity measures sensitive not only to species abundances but also to trait‐based species‐pairwise functional distances.
Chao, A   +7 more
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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