Results 131 to 140 of about 13,428,920 (391)

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms.

Genes & Development, 1994
In the last 10 years, a large family of secreted signaling molecules has been discovered that appear to mediate many key events in normal growth and development.
D. Kingsley
semanticscholar   +1 more source

Zero of the discrete beta function in SU(3) lattice gauge theory with color sextet fermions [PDF]

, 2008
We have carried out a Schrodinger functional calculation for the SU(3) lattice gauge theory with two flavors of Wilson fermions in the sextet representation of the gauge group.
Y. Shamir, B. Svetitsky, T. DeGrand
semanticscholar   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source

Self-Matching Properties of Beatty Sequences [PDF]

, 2006
We study the selfmatching properties of Beatty sequences, in particular of the graph of the function $\lfloor j\beta\rfloor $ against $j$ for every quadratic unit $\beta\in(0,1)$.
Masáková, Zuzana, Pelantová, Edita
core   +3 more sources

Beta-Bazilevič Function [PDF]

Sahand Communications in Mathematical Analysis
In this paper, we introduce a relatively new class, $\mathcal{\mathcal{B}}_{1}^\beta(\alpha)$, namely the class of Beta-Bazilevi\v{c} function is generated by the function Bazilevi\v{c} $\mathcal{B}_{1}(\alpha)$.
Sa'adatul Fitri, Mohamad Muslikh
doaj   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Parameter estimation for integer-valued Gibbs distributions

, 2020
We consider Gibbs distributions, which are families of probability distributions over a discrete space $\Omega$ with probability mass function given by $\mu^\Omega_\beta(x) = \frac{e^{\beta H(x)}}{Z(\beta)}$.
Harris, David G., Kolmogorov, Vladimir
core  

Monkeypox detection from skin lesion images using an amalgamation of CNN models aided with Beta function-based normalization scheme. [PDF]

PLoS One, 2023
Pramanik R, Banerjee B, Efimenko G, Kaplun D, Sarkar R.   +4 more
europepmc   +1 more source