Results 71 to 80 of about 1,115,045 (263)

Searching for beyond the Standard Model physics using the improved description of 100Mo $$2\nu \beta \beta $$ 2 ν β β decay spectral shape with CUPID-Mo

European Physical Journal C: Particles and Fields
The current experiments searching for neutrinoless double- $$\beta $$ β ( $$0\nu \beta \beta $$ 0 ν β β ) decay also collect large statistics of Standard Model allowed two-neutrino double- $$\beta $$ β ( $$2\nu \beta \beta $$ 2 ν β β ) decay events ...
C. Augier, A. S. Barabash, F. Bellini, G. Benato, M. Beretta, L. Bergé, J. Billard, Yu. A. Borovlev, L. Cardani, N. Casali, A. Cazes, E. Celi, M. Chapellier, D. Chiesa, I. Dafinei, F. A. Danevich, M. De Jesus, T. Dixon, L. Dumoulin, K. Eitel, F. Ferri, B. K. Fujikawa, J. Gascon, L. Gironi, A. Giuliani, V. D. Grigorieva, M. Gros, D. L. Helis, H. Z. Huang, R. Huang, L. Imbert, A. Juillard, H. Khalife, M. Kleifges, V. V. Kobychev, Yu. G. Kolomensky, S. I. Konovalov, J. Kotila, P. Loaiza, L. Ma, E. P. Makarov, P. de Marcillac, R. Mariam, L. Marini, S. Marnieros, X. F. Navick, C. Nones, E. B. Norman, E. Olivieri, J. L. Ouellet, L. Pagnanini, L. Pattavina, B. Paul, M. Pavan, H. Peng, G. Pessina, S. Pirro, D. V. Poda, O. G. Polischuk, S. Pozzi, E. Previtali, Th. Redon, A. Rojas, S. Rozov, V. Sanglard, J. A. Scarpaci, B. Schmidt, Y. Shen, V. N. Shlegel, F. Šimkovic, V. Singh, C. Tomei, V. I. Tretyak, V. I. Umatov, L. Vagneron, M. Velázquez, B. Ware, B. Welliver, L. Winslow, M. Xue, E. Yakushev, M. Zarytskyy, A. S. Zolotarova   +82 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

An endemic-epidemic beta model for time series of infectious disease proportions. [PDF]

J Appl Stat, 2022
Lu J, Meyer S.
europepmc   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Hippocampal Beta-Amyloid Accumulation In Aluminium Chloride and D-Galactose-Induced Rats: Establishing a Nontransgenic Alzheimer’s Model

Journal of Pharmacy and Bioallied Sciences
Background: Alzheimer’s disease (AD) is characterized by tau protein aggregation and beta-amyloid (Aβ) plaques leading to progressive cognitive decline.
Thirupathirao Vishnumukkala, Samaila M. Chiroma, Saravanan Jagadeesan, Prarthana K. Gopalakrishna, Sreenivasulu Sura, Nurul H. Mohd Nor, Mohamad A. Mohd Moklas   +6 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Compartmental analysis of the dynamics of beta-carotene metabolism in an adult volunteer.

Journal of Lipid Research, 1995
Metabolism of a 73 mumol oral dose of beta-carotene-d8 in olive oil was determined from plasma beta-carotene-d8 and retinol-d4 concentration-time curves in an adult male. beta-Carotene-d8 and retinol-d4 concentrations in serial plasma were measured using
J.A. Novotny, S.R. Dueker, L.A. Zech, A.J Clifford   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source