Results 71 to 80 of about 15,641,513 (303)
Bayesian spatial modeling for speeding likelihood using floating car trajectories
Journal of Traffic and Transportation Engineering (English ed. Online)Speeding likelihood is usually used to measure drivers' propensity of committing speeding. Albeit some studies have analyzed speeding likelihood, most of them are inadequate in considering spatial effects when analyzing speeding behaviors on urban road ...
Haiyue Liu +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Phi Beta Kappa Minutes, December 5, 1776-January 6,1781 [PDF]
Ledger of the Phi Beta Kappa minutes of meetings from December 5, 1776-January 6, 1781. These are the earliest meetings of Phi Beta Kappa.
Phi Beta Kappa
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La metafora. Testi greci e latini tradotti e commentati da Giulio Guidorizzi e Simone Beta
, 2000 Il volume consiste nello sviluppo e nel completamento di un lavoro pubblicato da Giulio Guidorizzi nel 1984 sotto forma di dispensa universitaria (Testi antichi sulla metafora), che consisteva in un'introduzione sul tropo della metafora nella cultura ...
GUIDORIZZI G., BETA, SIMONE
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Phi Beta Kappa: The Key Reporter Winter 2012-2013
, 2012 Announcement of the Beta of Nebraska chapter installation at Creighton University, p.
Phi Beta Kappa Society
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
, 1905 Phi Beta Kappa was founded by five students at the College of William and Mary in 1776. This minute book documents the organization in the period 1905-1928.
Phi Beta Kappa +1 more
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