Results 81 to 90 of about 2,443,019 (288)
Bayesian spatial modeling for speeding likelihood using floating car trajectories
Journal of Traffic and Transportation Engineering (English ed. Online)Speeding likelihood is usually used to measure drivers' propensity of committing speeding. Albeit some studies have analyzed speeding likelihood, most of them are inadequate in considering spatial effects when analyzing speeding behaviors on urban road ...
Haiyue Liu +5 more
doaj +1 more source
Gastrointestinal hyperplasia with altered expression of DNA polymerase beta.
PLoS ONE, 2009 BackgroundAltered expression of DNA polymerase beta (Pol beta) has been documented in a large percentage of human tumors. However, tumor prevalence or predisposition resulting from Pol beta over-expression has not yet been evaluated in a mouse model ...
Katsuhiko Yoshizawa +10 more
doaj +1 more source
Anyon Basis of c=1 Conformal Field Theory
, 1994 We study the $c=1$ conformal field theory of a free compactified boson with radius $r=\sqrt{\beta}$ ($\beta$ is an integer). The Fock space of this boson is constructed in terms of anyon vertex operators and each state is labeled by an infinite set of ...
Andric +30 more
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
, 2010 We propose a new method of the $\beta$-$\gamma$ constraint for quadrupole deformation in antisymmetrized molecular dynamics (AMD) to describe various cluster and shell-model structures in the ground and excited states of light nuclei.
Kanada-En'yo, Yoshiko, Suhara, Tadahiro
core +1 more source
Fluxon modeling of low-beta plasmas
Journal of Atmospheric and Solar-Terrestrial Physics, 2007 14 pages, 11 figures; also in press for ...
DeForest, Craig E. +1 more
openaire +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Off-Equilibrium Dynamics of a 4D Spin Glass with Asymmetric Couplings
, 1997 We study the off-equilibrium dynamics of the Edwards-Anderson spin glass in four dimensions under the influence of a non-hamiltonian perturbation. We find that for small asymmetry the model behaves as the hamiltonian one, while for large asymmetry the ...
Cugliandolo L +8 more
core +1 more source
Modeling human pancreatic beta cell dedifferentiation
Molecular Metabolism, 2018 Dedifferentiation could explain reduced functional pancreatic β-cell mass in type 2 diabetes (T2D).Here we model human β-cell dedifferentiation using growth factor stimulation in the human β-cell line, EndoC-βH1, and human pancreatic islets.Fibroblast growth factor 2 (FGF2) treatment reduced expression of β-cell markers, (INS, MAFB, SLC2A2, SLC30A8 ...
Marc Diedisheim +14 more
openaire +4 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source