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Mitochondrial fatty acid beta-oxidation [PDF]
EXCLI Journal : Experimental and Clinical SciencesPeripheral artery disease (PAD) is an atherosclerotic disease impacting over 200 million individuals and the prevalence increases with age. PAD occurs when plaque builds up within the peripheral arteries, leading to reduced blood flow and oxygen supply ...
Cassandra E. Bradley +7 more
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Development of oxaalkyne and alkyne fatty acids as novel tracers to study fatty acid beta-oxidation pathways and intermediates [PDF]
Journal of Lipid Research, 2022 Fatty acid beta-oxidation is a key process in mammalian lipid catabolism. Disturbance of this process results in severe clinical symptoms, including dysfunction of the liver, a major beta-oxidizing tissue.
Lars Kuerschner +5 more
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Identification of metabolites from peroxisomal beta-oxidation of prostaglandins.
Journal of Lipid Research, 1990 We have recently shown that isolated rat liver peroxisomes can chain-shorten prostaglandin F2 alpha and prostaglandin E2 to tetranor-metabolites. In the present report dinor-metabolites of these two prostaglandins were also identified, suggesting that ...
U Diczfalusy, SE Alexson
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Exercise and Berberine Intervention Ameliorate High-Fat Diet-Induced MAFLD by Regulating Gut Microbiota and Hepatic Fatty Acid Beta-Oxidation [PDF]
Journal of Inflammation ResearchXiaojian Zhang,1– 3,* Yanbin Cheng,4,* Qingyu Wei,5 Lixuan Sang,1,2 Quansheng Li5 1Department of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, 110022, People’s Republic of China; 2College of Exercise and ...
Zhang X, Cheng Y, Wei Q, Sang L, Li Q
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Frontiers in Cell and Developmental Biology, 2022 Peroxisomes are eukaryotic specific organelles that perform diverse metabolic functions including fatty acid β-oxidation, reactive species metabolism, photorespiration, and responses to stress. However, the potential regulation of these functions by post-
Amr Kataya +8 more
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Frontiers in Cell and Developmental Biology, 2022 Peroxisomes are dynamic multipurpose organelles with a major function in fatty acid oxidation and breakdown of hydrogen peroxide. Many proteins destined for the peroxisomal matrix contain a C-terminal peroxisomal targeting signal type 1 (PTS1), which is ...
Julia Ast +8 more
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Frontiers in Animal Science, 2022 We evaluated the mRNA expression of genes involved in hepatic fatty acid, amino acid, and mitochondrial energy metabolism in crossbred beef steers with divergent low and high residual feed intake (RFI).
Godstime Taiwo +5 more
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Shikonin Attenuates Hepatic Steatosis by Enhancing Beta Oxidation and Energy Expenditure via AMPK Activation. [PDF]
Nutrients, 2020 Gwon SY, Ahn J, Jung CH, Moon B, Ha TY.
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Deciphering Risperidone-Induced Lipogenesis by Network Pharmacology and Molecular Validation
Frontiers in Psychiatry, 2022 BackgroundRisperidone is an atypical antipsychotic that can cause substantial weight gain. The pharmacological targets and molecular mechanisms related to risperidone-induced lipogenesis (RIL) remain to be elucidated.
Yun Fu +6 more
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Peroxisomal ATP Uptake Is Provided by Two Adenine Nucleotide Transporters and the ABCD Transporters
Frontiers in Cell and Developmental Biology, 2022 Peroxisomes are essential organelles involved in various metabolic processes, including fatty acid β-oxidation. Their metabolic functions require a controlled exchange of metabolites and co-factors, including ATP, across the peroxisomal membrane.
Carlo W. T. van Roermund +4 more
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