Results 171 to 180 of about 481,631 (238)

Deep Brain Stimulation for VPS16‐Related Dystonia: A Multicenter Study

open access: yesAnnals of Neurology, EarlyView.
Objective The objective was to evaluate the effects of deep brain stimulation (DBS) in an international cohort of patients with VPS16‐related dystonia. Methods This observational study collected preoperative and postoperative demographic, clinical, stimulation, genetic, neuroimaging, and neurophysiological data of medically refractory DYT‐VPS16 ...
Tatiana Svorenova   +46 more
wiley   +1 more source

Advancing plant metabolic research by using large language models to expand databases and extract labeled data

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Premise Recently, plant science has seen transformative advances in scalable data collection for sequence and chemical data. These large datasets, combined with machine learning, have demonstrated that conducting plant metabolic research on large scales yields remarkable insights.
Rachel Knapp   +2 more
wiley   +1 more source

Technological Innovations and Applications of Spatial Transcriptomics in Livestock and Poultry Research

open access: yesAnimal Research and One Health, EarlyView.
The paper is divided into three main sections: a review of the development of spatial transcriptomics technology, its applications in livestock and poultry research, and its future prospects. This article provides an overview of the current state of spatial transcriptomics in animal research, exploring its integration with multiomics technologies as ...
Mingyu Wang   +5 more
wiley   +1 more source

Comparative Effectiveness of Abatacept versus Adalimumab in Shared Epitope positive and negative Rheumatoid Arthritis patients

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives The effect of the shared epitope (SE), and valine at position 11 (Val11) of HLA‐DRB1, on the activation of CD4+ T cells, is expected to be diminished by abatacept, a co‐stimulation blocker. However, published evidence on the value of genetic stratification for abatacept treatment is conflicting.
Chuan Fu Yap   +14 more
wiley   +1 more source

Impact of the COVID-19 Pandemic Mitigation Strategies on Cancer Treatment Trials: A Meta-Analysis of Industry and National Cancer Institute Studies. [PDF]

open access: yesJCO Oncol Adv
Unger JM   +12 more
europepmc   +1 more source

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