Results 1 to 10 of about 1,014,717 (317)

Newborn Screening Practices for Beta-Thalassemia in the United States

International Journal of Neonatal Screening, 2021
Beta-thalassemia, a heritable condition of abnormal hemoglobin production, is not a core condition on the United States Recommended Uniform Screening Panel (RUSP) for state and territorial newborn screening (NBS) programs.
Michael A. Bender, Mary Hulihan, Mary Christine Dorley, Maria del Pilar Aguinaga, Jelili Ojodu, Careema Yusuf   +5 more
doaj   +2 more sources

The survival rate of patients with beta-thalassemia major and intermedia and its trends in recent years in Iran [PDF]

Epidemiology and Health, 2018
OBJECTIVES Thalassemia is a common genetic disease in Iran, especially in the north and south of Iran. The present study sought to determine the survival rate of patients with thalassemia in highly endemic regions of Iran and its variation in patients ...
Alireza Ansari-Moghaddam, Hossein Ali Adineh, Iraj Zareban, Mehdi Mohammadi, Mahtab Maghsoodlu   +4 more
doaj   +2 more sources

Current status of beta‐thalassemia and its treatment strategies

Molecular Genetics & Genomic Medicine, 2021
Background Thalassemia is an inherited hematological disorder categorized by a decrease or absence of one or more of the globin chains synthesis. Beta‐thalassemia is caused by one or more mutations in the beta‐globin gene.
Shaukat Ali, Shumaila Mumtaz, Hafiz Abdullah Shakir, Muhammad Khan, Hafiz Muhammad Tahir, Samaira Mumtaz, Tafail Akbar Mughal, Ali Hassan, Syed Akif Raza Kazmi, Sadia, Muhammad Irfan, Muhammad Adeeb Khan   +11 more
doaj   +2 more sources

Beta-thalassemia

Genetics in Medicine, 2023
Beta-thalassemia is caused by the reduced (beta+) or absent (beta0) synthesis of the beta globin chains of the hemoglobin tetramer. Three clinical and hematological conditions of increasing severity are recognized, i.e., the beta-thalassemia carrier ...
A. Cao, R. Galanello
semanticscholar   +1 more source

Epidemiology of clinically significant forms of alpha‐ and beta‐thalassemia: A global map of evidence and gaps

American journal of hematology/oncology, 2023
This systematic literature review assessed the global prevalence and birth prevalence of clinically significant forms of alpha‐ and beta‐thalassemia. Embase, MEDLINE, and the Cochrane Library were searched for observational studies published January 1 ...
K. Musallam, L. Lombard, K. Kistler, María Arregui, K. Gilroy, Christina X. Chamberlain, E. Zagadailov, K. Ruiz, A. Taher   +8 more
semanticscholar   +1 more source

Venous thromboembolism risk assessment among beta-thalassemia patients

Journal of Applied Hematology, 2023
BACKGROUND: Thromboembolic (TE) disorders are among the most common complications of beta-thalassemia. We designed this cross-sectional study to investigate the state of hypercoagulability and platelet activation in patients with beta-thalassemia ...
Hasnaa A Abo-Elwafa, Laila M Youseff, Ramadan A Mahmoud, Mahmoud I Elbadry, Ahmed Tawfeek, Shereen P Aziz   +5 more
doaj   +1 more source

Evaluation of Srivastava index to distinguishing Beta-Thalassemia Trait from Iron Deficiency

Pakistan Journal of Medical & Health Sciences, 2022
Objective: To assist in the differential diagnosis of beta thalassemia trait and iron deficiency anaemia, many alternative red blood cell index-based formulae were examined.
Hassnain Shahid, M. Saleem, N. Naseer, Samina Tabussam, Atif Aziz, Saeed Ullah   +5 more
semanticscholar   +1 more source

Alpha‐globin gene triplication and its effect in beta‐thalassemia carrier, sickle cell trait, and healthy individual

eJHaem, 2021
The genotype and phenotype correlation between coinheritance of heterozygous beta‐thalassemia with the alpha‐globin triplication is unclear. In this study we have investigated and reviewed alpha triplication frequency in beta‐thalassemia carriers, sickle
Mohammad Hamid, Bijan keikhaei, Hamid Galehdari, Alihossein Saberi, Alireza Sedaghat, Gholamreza Shariati, Marziye Mohammadi‐Anaei   +6 more
doaj   +1 more source

Prevalence of iron deficiency anemia and beta thalassemia carriers among relatives of beta thalassemia patients in Nile Delta region, Egypt: a multicenter study

Journal of Egyptian Public Health Association, 2021
Background Screening of β thalassemia among close relatives is more feasible in highly prevalent countries with limited resources. The purpose of this study is to determine the prevalence of β thalassemia carriers and iron deficiency anemia among ...
M. El-Shanshory, L. Sherief, H. Hassab, S. Ragab, S. Yahia, A. Mansour, A. S. Ahmed, S. Abdou, Amal M. Helmy, M. Watany, Ahmed M. Gad ALllah, M. A. Guindy, Z. Mourad, M. Soliman, R. El-Farahaty, F. El-Dahtory, A. Darwish, Suzy Abd Elmabood, I. Kabbash, Shimaa M. Saied   +19 more
semanticscholar   +1 more source

How early can myocardial iron overload occur in Beta thalassemia major? [PDF]

, 2014
BACKGROUND: Myocardial siderosis is the most common cause of death in patients with beta thalassemia major(TM). This study aimed at investigating the occurrence, prevalence and severity of cardiac iron overload in a young Chinese population with beta TM.
A Aessopos, AM Maceira, AW Leung, B Modell, B Modell, B Modell, BA Davis, C Borgna-Pignatti, DH Fitchett, DJ Weatherall, DT Kremastinos, F Alpendurada, G Barosi, Gaohui Yang, GM Brittenham, GM Brittenham, HF Pan, Hongfei Pan, JC Wood, JC Wood, JC Wood, JL Fernandes, K Tziomalos, Liling Long, Lisa Anderson, LJ Anderson, LJ Anderson, M Angastiniotis, M Bejaoui, M Westwood, MA Aldouri, MA Tanner, MA Tanner, MA Tanner, MAEM Engle, NF Olivieri, P Kirk, Peng Peng, Q Meng, Rongrong Liu, Shaohong Tan, T He, Taigang He, V Positano, Weijia Yang, Xiaolei Xu, Xingjiang Long, Xinhua Zhang, Yong-rong Lai, Yongrong Lai   +49 more
core   +6 more sources