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The survival rate of patients with beta-thalassemia major and intermedia and its trends in recent years in Iran [PDF]
Epidemiology and Health, 2018 OBJECTIVES Thalassemia is a common genetic disease in Iran, especially in the north and south of Iran. The present study sought to determine the survival rate of patients with thalassemia in highly endemic regions of Iran and its variation in patients ...
Alireza Ansari-Moghaddam +4 more
doaj +2 more sources
Newborn Screening Practices for Beta-Thalassemia in the United States
International Journal of Neonatal Screening, 2021 Beta-thalassemia, a heritable condition of abnormal hemoglobin production, is not a core condition on the United States Recommended Uniform Screening Panel (RUSP) for state and territorial newborn screening (NBS) programs.
Michael A. Bender +5 more
doaj +2 more sources
Current status of beta‐thalassemia and its treatment strategies
Molecular Genetics & Genomic Medicine, 2021 Background Thalassemia is an inherited hematological disorder categorized by a decrease or absence of one or more of the globin chains synthesis. Beta‐thalassemia is caused by one or more mutations in the beta‐globin gene.
Shaukat Ali +11 more
doaj +2 more sources
Genetics in Medicine, 2023 Beta-thalassemia is caused by the reduced (beta+) or absent (beta0) synthesis of the beta globin chains of the hemoglobin tetramer. Three clinical and hematological conditions of increasing severity are recognized, i.e., the beta-thalassemia carrier ...
A. Cao, R. Galanello
semanticscholar +1 more source
American journal of hematology/oncology, 2023 This systematic literature review assessed the global prevalence and birth prevalence of clinically significant forms of alpha‐ and beta‐thalassemia. Embase, MEDLINE, and the Cochrane Library were searched for observational studies published January 1 ...
K. Musallam +8 more
semanticscholar +1 more source
Venous thromboembolism risk assessment among beta-thalassemia patients
Journal of Applied Hematology, 2023 BACKGROUND: Thromboembolic (TE) disorders are among the most common complications of beta-thalassemia. We designed this cross-sectional study to investigate the state of hypercoagulability and platelet activation in patients with beta-thalassemia ...
Hasnaa A Abo-Elwafa +5 more
doaj +1 more source
Evaluation of Srivastava index to distinguishing Beta-Thalassemia Trait from Iron Deficiency
Pakistan Journal of Medical & Health Sciences, 2022 Objective: To assist in the differential diagnosis of beta thalassemia trait and iron deficiency anaemia, many alternative red blood cell index-based formulae were examined.
Hassnain Shahid +5 more
semanticscholar +1 more source
eJHaem, 2021 The genotype and phenotype correlation between coinheritance of heterozygous beta‐thalassemia with the alpha‐globin triplication is unclear. In this study we have investigated and reviewed alpha triplication frequency in beta‐thalassemia carriers, sickle
Mohammad Hamid +6 more
doaj +1 more source
Studies on molecular spectrum of beta thalassemia among residents of Chennai
AIMS Molecular Science, 2022 Beta thalassemia is caused by a mutation in the human beta globin gene. More than 400 causative mutations have been characterized in the Hemoglobin Subunit Beta (HBB) gene.
Bhuvana Selvaraj +4 more
doaj +1 more source
Definitions, 2020 The signs and symptoms of thalassemia major appear within the first 2 years of life. Children develop life-threatening anemia. They do not gain weight and grow at the expected rate (failure to thrive) and may develop yellowing of the skin and whites of ...
Antonio Piga +3 more
semanticscholar +1 more source