Results 21 to 30 of about 1,014,717 (317)
International Journal of Molecular Sciences, 2020 Thalassemia syndromes are characterized by the inability to produce normal hemoglobin. Ineffective erythropoiesis and red cell transfusions are sources of excess iron that the human organism is unable to remove.
V. Pinto, G. Forni
semanticscholar +1 more source
Molecular Genetics & Genomic Medicine, 2020 Background Hepcidin and hemochromatosis (HFE) are iron regulatory proteins that are encoded by HAMP and HFE genes. Mutation in either HAMP gene or HFE gene causes Hepcidin protein deficiency that can lead to iron overload in beta thalassemia patients ...
Maryam Shah +7 more
doaj +1 more source
Rare Co-occurrence of Beta-Thalassemia and Pseudoxanthoma elasticum: Novel Biomolecular Findings
Frontiers in Medicine, 2020 A number of beta-thalassemia patients, independently from the type of beta-thalassemia (β0 or β+) and blood transfusion requirements, may develop, after puberty, dermal, cardiovascular, and ocular complications associated with an ectopic mineralization ...
F. Boraldi +4 more
semanticscholar +1 more source
SKRINING THALASSEMIA BETA MINOR PADA MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS SRIWIJAYA
Jurnal Kedokteran dan Kesehatan, 2021 Berdasarkan data dari World Health Organization (WHO) tahun 2001, terdapat 7% populasi di seluruh dunia yang merupakan karier thalassemia atau penderita thalassemia minor. Di Indonesia, frekuensinya pun cukup tinggi yaitu 3-10%.
Medina Athiah +2 more
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Alpha and beta-Thalassemia mutations in Hubei area of China
BMC Medical Genetics, 2020 BackgroundThalassemia is a group of inherited hemoglobic disorders resulting from defectsin the synthesis of one or more of the hemoglobin chains, which is one of the most prevalent inherited disorders in southern China.
Yao-wu Zhu +4 more
semanticscholar +1 more source
Advanced Medical Journal, 2022 Background and objectives: The identification of carriers of beta- thalassemia depends on the detection of a high level of hemoglobin A2. The hemoglobin A2 level is influenced by some elements including iron.
Awaz Ahmed Kamal Shalli +2 more
doaj +1 more source
.BETA.+-Thalassemia with Hemochromatosis.
Internal Medicine, 1992 A 64-year-old man was admitted due to ascites. Laboratory data showed hemoglobin 6.7 g/dl, mean corpuscular volume 82 fl, and ferritin 2,360 ng/ml. Liver biopsy showed hemochromatosis. The diagnosis of beta-thalassemia was suggested by a decreased ratio of beta/alpha-globin synthesis in vitro (0.26).
Masakatsu UCHIHARA +11 more
openaire +4 more sources
TyG index and insulin resistance in beta-thalassemia [PDF]
, 2015 Insulin resistance (IR) underlies some glucose metabolism abnormalities in thalassemia major. Recently, triglyceride glucose index (TyG) has been proposed for evaluating insulin resistance as a simple, low cost, and accessible tool.
Fayaz, M. +3 more
core +1 more source
Beta-Thalassemia major and pregnancy
Bratislava Medical Journal, 2013 It was studied the clinical management and the medical outcomes of 6 pregnancies in 5 women affected by Beta Thalassemia major, based on last guidelines and pharmacological treatments.Paediatric Department and Department of Obstetrics and Gynaecology of the University of Catania.These patients were taken among a group of 116 women affected by beta ...
Gulino F. A. +5 more
openaire +8 more sources
AIMS Molecular Science, 2021 Hereditary Hemochromatosis (HH) is an autosomal recessive disorder of iron metabolism associated with HFE gene mutations, characterized by increased iron absorption and accumulation leading to multi-organ damage caused by iron overload toxicity.
Bhuvana Selvaraj +4 more
doaj +1 more source