Results 51 to 60 of about 1,051,766 (308)

Differentiation of beta thalassemia trait from iron deficiency anemia by hematological indices

open access: yesPakistan Journal of Medical Sciences, 2017
Objective: We aimed at finding out reliable parameter in the differentiation of iron deficiency anemia (IDA) and beta-thalassemia trait (β-TT) in the adult population subjected to Saudi Arabian Premarital Screening Program. Methods: A total of 620 adults
T. Jameel   +4 more
semanticscholar   +1 more source

Effect of zinc supplementation on serum mlondealdehyde and lipid profiles on beta thalassemia major patients [PDF]

open access: yes, 2012
Objectives: Thalassemic patients are seriously at risk of serum dislipidemia, zinc deficiency and tissue damage due to oxidative stress induced by iron storage.
Aboomardani, M.   +3 more
core  

Synthetic Lethal Therapy Based on Dimorphism for Systemic Infection of Drug‐Resistant Candida albicans

open access: yesAdvanced Science, EarlyView.
To tackle the alarming mortality rate linked to Candida albicans infections, a synthetic lethal strategy precisely aimed at the two distinct forms of this fungus: yeast and hyphae is formulated. Ultimately, through the innovative use of macrophage membranes for drug delivery, the effectiveness of this strategy is substantially boosted while ...
Yang Gao   +12 more
wiley   +1 more source

Prevalence of Co-Inheritance of Alpha-Thalassemia with Beta-Thalassemia and Beta-Hemoglobinopathy in Ahvaz City

open access: yesJournal of Ardabil University of Medical Sciences, 2013
Background: Co-inheritance of hemoglobin gene defects is a rare important status that can lead to double heterozygote or homozygote with significant clinical manifestations. Such conditions can be observed in co-inheritance of alpha-thalassemia with beta-
Najmaddin Saki   +8 more
doaj  

Rare double heterozygosity for poly A(A>G) and CD17(A>T) of beta thalassemia intermedia in a Chinese family

open access: yesHematology Reports, 2019
Beta thalassemia is a hereditary disorder resulted from mutations in the β globin gene leading to alpha/beta imbalance, ineffective erythropoiesis, and chronic anemia.
Jianhong Xie   +5 more
doaj   +1 more source

Premature atherosclerosis in children with beta-thalassemia major: New diagnostic marker

open access: yesBMC Pediatrics, 2017
BackgroundEarly vascular alteration, atherosclerosis and coronary artery disease have emerged as important cardiovascular complications among beta-thalassemia major (B-TM) patients. The aims of the current study were to assess the prevalence of premature
L. Sherief   +9 more
semanticscholar   +1 more source

Chronic hyperplastic anemia as an independent risk factor for atherosclerotic lesions: a lesson from thalassemia intermedia [PDF]

open access: yes, 2010
Introduction. Cardiovascular involvement represents a well-known complication and the primary cause of mortality, both in transfusion-dependent beta thalassemia major (β-TM) and in transfusion-independent beta thalassemia intermedia (β-TI ...
Alessandra Spiga   +7 more
core   +1 more source

The history of beta-thalassemia in Turkey

open access: yesThe Turkish Journal of Pediatrics, 1991
The first two patients with beta-thalassemia major in Turkey, were reported in 1941. However, the importance of beta-thalassemia as a health problem was brought to the attention of physicians only after 1950.
M Aksoy
doaj  

Beta thalassemia - a review

open access: yesJournal of Pathology of Nepal, 2014
Thalassemia is a globin gene disorder that results in a diminished rate of synthesis of one or more of the globin chains. About 1.5% of the global population (80 to 90 million people) are carriers of beta Thalassemia.
R Jha, S Jha
doaj   +1 more source

One-step genetic correction of hemoglobin E/beta-thalassemia patient-derived iPSCs by the CRISPR/Cas9 system

open access: yesStem cell research & therapeutics, 2018
BackgroundThalassemia is the most common genetic disease worldwide; those with severe disease require lifelong blood transfusion and iron chelation therapy.
Methichit Wattanapanitch   +8 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy