Results 81 to 90 of about 5,832,501 (223)

Evaluation of physical growth of Patient WithThalassemia Major Based on NCHS criteria [PDF]

Background: Beta thalassemia major, including the conditions in which the natural growth due to complications from those diseases can be disrupted. Despite the recent advances in treating these patients, growth retardation in a significant percentage of ...
آریش, گیتی, اللهیاری, ایراندخت, سیدجوادی, مهری, مظاهری, عفت, محمدی, راحله   +4 more
core  

The Presence and Percentage of Circulating Nucleated Red Blood Cells Reveal Distinct Characteristics in Adults With Sickle Cell Disease

American Journal of Hematology, Volume 101, Issue 12, Page 2961-2975, December 2026.
ABSTRACT Although circulating nucleated red blood cells (cNRBCs) have previously been detected in patients with sickle cell disease (SCD), their prevalence and clinical significance during steady‐state disease have not been established. We retrospectively analyzed 270 adults with an SS or Sβ0‐thalassemia genotype.
Ugo Boccadifuoco, Ivan Lerner, Auria Godard, Luc Darnige, Laure Joseph, Wassim El Nemer, Geoffrey Cheminet, Jean‐Benoit Arlet   +7 more
wiley   +1 more source

Genotype–phenotype correlation among beta-thalassemia and beta-thalassemia/HbE disease in Thai children: predictable clinical spectrum using genotypic analysis

, 2018
Chanchai Traivaree,1 Chalinee Monsereenusorn,1 Piya Rujkijyanont,1 Warakorn Prasertsin,2 Boonchai Boonyawat3 1Division of Hematology/Oncology, Department of Pediatrics, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand; 2Department of ...
Rujkijyanont P, Boonyawat B, Traivaree C, Monsereenusorn C, Prasertsin W   +4 more
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Therapeutic Value of Silymarin as Iron Chelator in Children with Beta Thalassemia with Iron Overload

Mediterranean Journal of Hematology and Infectious Diseases, 2014
Beta thalassemia is an inherited hemoglobin disorder resulting in chronic hemolytic anemia. The most common treatment for thalassemia is blood transfusion which is necessary to provide the patients with healthy red blood cells containing normal ...
adel abd elhaleim hagag
doaj  

Multiclass classification of thalassemia types using complete blood count and HPLC data with machine learning

Scientific Reports
Mild to severe anemia is caused by thalassemia, a common genetic disorder affecting over 100 countries worldwide, that results from the abnormality of one or several of the four globin genes. This leads to chronic hemolytic anemia and disrupted synthesis
Muhammad Umar Nasir, Muhammad Zubair, Muhammad Tahir Naseem, Tariq Shahzad, Ahmed Saeed, Khan Muhammad Adnan, Amir H. Gandomi   +6 more
doaj   +1 more source

Examination and Sampling of Chorionic Villi for the Diagnosis of Beta-Thalassemia Major in the First Trimester of Pregnancy in Southwestern Iran

Armaghane Danesh Bimonthly Journal, 2022
Background & aim: Beta thalassemia is one of the most common hereditary diseases in Iran. The birth of a child with thalassemia causes many social and economic problems for parents and the health care system.
E Shams, M AllahDadian, Z Yadegari Baharanchi, M Harfsheno   +3 more
doaj  

[Beta thalassemia major in Argentina].

Medicina, 2002
An analysis of beta thalassemia major patients seen at Hospital Juan P. Garrahan was carried out in order to determine the characteristics and outcome of the population. From August 1987 to July 2000, 45 patients were admitted (27 males-18 females). The most common beta globin gene defects were C-39 (30.7%); IVS-I nt 110 (20%); IVS-I nt 6 (13.3%); IVS ...
Feliu Aurora, Torres, Mariana, Bonduel, Gabriela, Sciuccati, Ana, del Pozo, Ariel, Roldán, Marta, Ciaccio, Virginia, Orazi, Virginia, Fano, Blanca, Ozuna, Horacio, Lejarraga, Sackmann Federico, Muriel   +10 more
openaire   +1 more source

HOPE Kids 2: Phase 3, Randomized Trial of Voxelotor in Children With SCD and Conditional Cerebral Blood Flow Velocities

American Journal of Hematology, Volume 101, Issue 11, Page 2799-2811, November 2026.
ABSTRACT Children with SCD have elevated stroke risk, correlated with cerebral blood flow velocity (CBFV). HOPE Kids 2 was a phase 3, multicenter, double‐blind, placebo‐controlled trial evaluating the effect of voxelotor on CBFV. Participants aged 2 to < 15 years with SCD (HbSS/HbSβ0) and conditional CBFV (170 to < 200 cm/s) were randomized 1:1 to ...
Halima Bello‐Manga, Shehu Umar Abdullahi, Hoda Hassab, Biobele Brown, Videlis Nduba, Jessie Githanga, Adeseye Michael Akinsete, Amal El‐Beshlawy, Diana Hanna, Catherine Segbefia, Iheanyi Okpala, Azza Tantawy, Bernhards Ogutu, Venée N. Tubman, Vivian Paintsil, Yasser Wali, Mohammed Essa, Paul Telfer, Sandy Dixon, Anne Hickman, Jennifer F. Doss, Mark W. Davis, Jeremy Rupon, Fenella J. Kirkham, R. Clark Brown, on behalf of the HOPE Kids 2 Investigators, Amal El‐Beshlawy, Mohamed Badr, Diana Hanna*, Hoda Hassab, Azza Tantawy, Vivian Paintsil, Catherine Segbefia, Raffaella Colombatti, Daniela Cuzzubbo, Silverio Perrotta, Jessie Githanga, Videlis Nduba, Bernhards Ogutu, Shehu Umar Abdullahi, Adeseye Michael Akinsete, Halima Bello‐Manga, Biobele Brown, Iheanyi Okpala, Yasser Wali, Mohammed Essa, Banu Kaya, Paul Telfer, Ofelia Alvarez, Natasha Archer, Shayla Bergmann, R Clark Brown, Andrew Campbell, Carlton Dampier*, Richard Hurwitz, Erin Jackson, Janet Kwiatkowski, Melissa M. McNaull*, Venée N. Tubman   +58 more
wiley   +1 more source

Factors associated with continuing emergence of β-thalassemia major despite prenatal testing: a cross-sectional survey

, 2017
Haleama Al Sabbah,1 Sarah Khan,1 Abdallah Hamadna,2 Lamia Abu Ghazaleh,2 Anwar Dudin,2 Bashar Adnan Karmi3 1College of Natural and Health Sciences, Zayed University, Dubai, UAE; 2Faculty of Medicine, An-Najah National University, Nablus, Palestine ...
Al Sabbah H, Hamadna A, Dudin A, Karmi BA, Abu Ghazaleh L, Khan S   +5 more
core  

Whole exome sequencing and rare variant association study to identify genetic modifiers, KLF1 mutations, and a novel double mutation in Thai patients with hemoglobin E/beta-thalassemia

, 2023
Clinical manifestations of patients with Hemoglobin E/beta-thalassemia vary from mild to severe phenotypes despite exhibiting the same genotype. Studies have partially identified genetic modifiers.
Kittiphong Paiboonsukwong (5774672), Nawaporn Tansiri (14836554), Surasak Sawatnatee (14836557), Wikanda Pholmoo (14836590), Supawee Saengboon (13010646), Kanyaporn Charoenprasert (14836566), Wichuda Thamprasert (14836569), Nisachon Khorwanichakij (14836581), Chayamon Takpradit (14836560), Narumol Nolwachai (14836572), Wannaphorn Rotchanapanya (6280742), Saranya Pongudom (14836563), Wanlapa Rattanasawat (14836575), Noppadol Siritanaratkul (6413990), Bhoom Suktitipat (202143), Putchong Saetow (14836584), Chanin Limwongse (145689), Krittichat Kamjornpreecha (14836587), Manop Pithukpakorn (744798), Boonyanuch Dujjawan (14836593), Yingyong Chinthammitr (11857510), Busakorn Sae-Aeng (14836578), Chattree Hantaweepant (14836551)   +22 more
core   +1 more source