Results 101 to 110 of about 26,664 (228)

Prevalence of orofacial changes in patients with β-thalassemia major in Karbala City, Iraq [PDF]

open access: yes, 2014
Objectives: The aim of this study was to investigate findings of oral abnormalities or changes in these patients, and compare it to healthy control subjects.
Muhanned Salah Abulsattar   +1 more
core   +2 more sources

Safety and Efficacy of Iron Chelators in Patients With Chronic Kidney Disease: A Systematic Review and Meta‐Analysis

open access: yesHemodialysis International, EarlyView.
ABSTRACT Background Iron overload in chronic kidney disease contributes to oxidative injury. The role of iron chelators, standard in transfusion‐related overload, remains unclear in chronic kidney disease. Aim To evaluate the efficacy and safety of iron chelators in adults with chronic kidney disease.
Humam Emad Rajha   +6 more
wiley   +1 more source

A retrospective analysis of the antigen‐negative red blood cell supply conducted at a single centre in China

open access: yesTransfusion Medicine, EarlyView.
Abstract Objective This study aimed to analyse the distribution and demand patterns of antigen‐negative red blood cells (RBCs) in Shandong Province, China (2022–2024), with a focus on ABO blood groups and clinically significant antigens. The research was designed to provide rigorous data for advancing precision transfusion protocols and to establish a ...
Aiping Zhao   +7 more
wiley   +1 more source

Rare double heterozygosity for poly A(A>G) and CD17(A>T) of beta thalassemia intermedia in a Chinese family

open access: yesHematology Reports, 2019
Beta thalassemia is a hereditary disorder resulted from mutations in the β globin gene leading to alpha/beta imbalance, ineffective erythropoiesis, and chronic anemia.
Jianhong Xie   +5 more
doaj   +1 more source

Hyperhemolysis in a patient with β-thalassemia major

open access: yesAsian Journal of Transfusion Science, 2009
A case of hyperhemolysis in a 2-year-old boy with beta thalassemia major was noted. After several transfusions, he developed hyperhemolysis with a positive (C3d only) direct antiglobulin test (DAT) and no clinically significant RBC allo- or auto-antibodies. (There was a weak cold antibody, showing a narrow thermal range).
Morawakage, Lakmali R.   +3 more
openaire   +2 more sources

A global survey of blood transfusion practices for patients with sickle cell disease

open access: yesTransfusion, EarlyView.
Abstract Background Sickle cell disease (SCD) affects over 7 million people globally, with blood transfusion remaining a cornerstone of management. However, contemporary transfusion practices across diverse settings remain poorly characterized. We evaluated global transfusion practices for patients with SCD to identify gaps and inform resource ...
Jeremy W. Jacobs   +18 more
wiley   +1 more source

Thalassemias in South Asia: clinical lessons learnt from Bangladesh

open access: yesOrphanet Journal of Rare Diseases, 2017
Thalassemias are emerging as a global public health concern. Due to remarkable success in the reduction of childhood mortality by controlling infectious diseases in developing countries, thalassemias are likely to be a major public health concern in the ...
Mohammad Sorowar Hossain   +12 more
doaj   +1 more source

Myelodysplastic Syndromes: 2026 Update on Diagnosis, Risk‐Stratification and Management

open access: yesAmerican Journal of Hematology, Volume 101, Issue 9, Page 2393-2411, September 2026.
ABSTRACT Disease Overview The myelodysplastic syndromes (MDS) are a heterogeneous group of myeloid disorders characterized by peripheral blood cytopenias and increased risk of transformation to acute myelogenous leukemia (AML). MDS occurs more frequently in older males and in individuals with prior exposure to cytotoxic therapy.
Guillermo Garcia‐Manero
wiley   +1 more source

Beta Globin Frameworks in Thalassemia Major Patients from North Iran [PDF]

open access: yes, 2013
Objective: Four combinations of five neutral sequence changes at rs713040, rs10768683, rs7480526, rs7946748, and rs1609812 occurring in the human beta globin gene defined as frameworks have been reported in beta globin gene.
Azizi, Mandana   +2 more
core   +3 more sources

Hemoglobin D/beta-thalassemia and beta-thalassemia major in a Saudi family.

open access: yesSaudi medical journal, 2008
The present report describes the clinical, hematological and molecular characteristics in a family with unique interaction between 3 different mutations discovered during routine workup for bone marrow transplantation. In this report, complete hematological and molecular studies were performed for a large Saudi family.
Tarek M, Owaidah   +2 more
openaire   +1 more source

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