Results 91 to 100 of about 5,832,501 (223)

Myocarditis in β-Thalassemia Major

Circulation, 1995
Background Although acute pericarditis is a common complication of β-thalassemia major, the prevalence and consequences of myocarditis in this disease have not been investigated. Methods and Results A prospective 5-year follow-up study
KREMASTINOS, DT, TINIAKOS, G, THEODORAKIS, GN, KATRITSIS, DG, TOUTOUZAS, PK   +4 more
openaire   +3 more sources

The Primary Reasons People Participate in Maternal‐Fetal Phase I Clinical Trials Are Psychosocial

Ethics &Human Research, Volume 48, Issue 6, Page 20-31, November–December 2026.
ABSTRACT Recent critiques of ethical guidance for maternal‐fetal therapy clinical trials has highlighted the need to weigh maternal, fetal, and societal interests, respectively, while deprioritizing psychosocial reasons for participation. Psychosocial reasons refer to the psychological and social influences on study participants’ decisions, and they ...
Julia E. H. Brown, Leslie S. Riddle, Emma Canepa, Billie Lianoglou, Dawn Gano, Teresa N. Sparks, Jodi Halpern   +6 more
wiley   +1 more source

Demographic and Nutritional Profile of Thalassemia Carrier and Non‐Carrier Young Children in Bangladesh: A Comparative Study

Food Science &Nutrition, Volume 14, Issue 11, November 2026.
The study assessed the demographic and nutritional profiles of children aged 2–5 years with and without thalassemia carrier status in Belkuchi, Sirajganj, Bangladesh. Thalassemia carrier children had significantly lower height‐for‐age z‐scores (HAZ), indicating poorer linear growth.
Sabuktagin Rahman, Farhana Rinky, Santhia Ireen, Faruk Ahmed   +3 more
wiley   +1 more source

ALPHA-THALASSEMIA AND BETA-THALASSEMIA IN A TURKISH FAMILY

, 1977
A Turkish family is described in which 3 children have a clinical picture similar to that of thalassemia major, with typical red cell morphology and indices, and with about 10% Hb Bart''s but without measurable amounts of Hb H.
HUISMAN, THJ, YETGIN, SEVGİ, ALTAY, C, SAY, B   +3 more
core   +1 more source

Comparison of Right and Left Side Heart Functions in Patients with Thalassemia Major, Patients with Thalassemia Intermedia, and Control Group

Journal of Tehran University Heart Center, 2015
Background: Heart disease is the main cause of mortality and morbidity in patients with beta thalassemia, rendering its early diagnosis vital. We studied and compared echocardiographic findings in patients with beta thalassemia major, patients with beta ...
Noormohammad Noori, Mehdi Mohamadi, Kambiz Keshavarz, SeyedMostafa Alavi, Maziar Mahjoubifard, Yalda Mirmesdagh   +5 more
doaj  

CRISPR Technology: From Bench to Bedside Applications

MedComm, Volume 7, Issue 11, November 2026.
This review systematically dissects the molecular mechanisms, advantages, and limitations of core CRISPR editing platforms including base editors (Panel A) and prime editing (Panel B); summarizes pivotal clinical data across hemoglobinopathies, CAR‐T immunotherapy, muscular dystrophy, cystic fibrosis, cardiometabolic diseases, and rare monogenic ...
Xinzhi Ma, Lingyu Li, Yingli Sun
wiley   +1 more source

Mirror aneurysms of extracranial internal carotid arteries in a patient with beta-thalassemia major

, 2020
Beta-thalassemia major is a chronic disorder characterised by severe anemia. This patient with beta-thalassemia major is the first magnetic resonance (MR) angiographic case for symmetric mirror aneurysms of the extracranial internal carotid arteries. For
Ogul, Yasemin, GÜVEN, Fadime, Taydas, Onur, OĞUL, Hayri, Ogul, Hayri/   +4 more
core   +1 more source

Genotypic‐Phenotypic Correlations in Non‐HbE β‐Thalassemia Intermedia: A Geographic Systematic Review

Molecular Genetics &Genomic Medicine, Volume 14, Issue 11, November 2026.
β‐Thalassemia intermedia exhibits distinct region‐specific molecular patterns shaped by three interacting genetic axes: β‐globin mutation severity, HbF‐inducing modifiers, and α‐globin gene dosage. Mediterranean populations are predominantly mutation‐driven, Middle Eastern populations rely on HbF compensation, and Asian populations are governed by ...
Kavindya Fernando, Shiromi Perera, Anuja Premawardhena   +2 more
wiley   +1 more source

Growth Failure in Thalassemia Major Patients in Samples of Iraqi Patients [PDF]

Introduction: Thalassemia, a hereditary autosomal recessive blood disorder, arises from genetic abnormalities leading to a diminished synthesis rate of one of the globin chains constituting hemoglobin.
Shaima’A Dakhel ABDULHASSAN
core   +2 more sources

Thalassemias in South Asia: clinical lessons learnt from Bangladesh

Orphanet Journal of Rare Diseases, 2017
Thalassemias are emerging as a global public health concern. Due to remarkable success in the reduction of childhood mortality by controlling infectious diseases in developing countries, thalassemias are likely to be a major public health concern in the ...
Mohammad Sorowar Hossain, Enayetur Raheem, Tanvira Afroze Sultana, Shameema Ferdous, Nusrat Nahar, Sazia Islam, Mohammad Arifuzzaman, Mohammad Abdur Razzaque, Rabiul Alam, Sonia Aziz, Hazera Khatun, Abdur Rahim, Manzur Morshed   +12 more
doaj   +1 more source