Results 1 to 10 of about 37,714 (159)

Paradoxical G-quadruplex distribution in coronavirus genomes reveals functional constraints and antiviral therapeutic opportunities [PDF]

Virus Research
We computationally characterized G-quadruplex (G4) distributions across 31 coronavirus genomes to identify conserved structural features as potential antiviral therapeutic targets.
Masato Tanigawa, Takafumi Iwaki
doaj   +2 more sources

Detection of avian, murine, bovine, shrew, and bat coronaviruses in wild mammals from Mexico [PDF]

Virology Journal
Coronaviruses infect a wide range of animal and human hosts. Some human coronaviruses, such as SARS-CoV, MERS-CoV, and SARS-CoV-2, originated in animals, with bats often serving as ancestral hosts.
Jocelyn Medina-Gudiño, Yolanda López-Vidal, J. Adolfo Pardo-Tovar, Lauro Velázquez-Salinas, Francisco Javier Basurto-Alcántara   +4 more
doaj   +2 more sources

Genomic characterization and cross-species transmission potential of hedgehog coronavirus [PDF]

One Health
In the 21st century, three betacoronaviruses (SARS-CoV, MERS-CoV and SARS-CoV-2) have emerged in humans worldwide as a result of animal spillover, causing severe respiratory infections and resulting in more than seven million deaths.
Andreia V.S. Cruz, Sérgio Santos-Silva, Luís Queirós-Reis, Clarisse Rodrigues, Vanessa Soeiro, Rachael E. Tarlinton, João R. Mesquita   +6 more
doaj   +2 more sources

Genomic Feature Analysis of Betacoronavirus Provides Insights Into SARS and COVID-19 Pandemics

Frontiers in Microbiology, 2021
In December 2019, the world awoke to a new betacoronavirus strain named severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Betacoronavirus consists of A, B, C and D subgroups.
Xin Li, Jia Chang, Shunmei Chen, Liangge Wang, Tung On Yau, Qiang Zhao, Zhangyong Hong, Jishou Ruan, Guangyou Duan, Shan Gao   +9 more
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Seasonality of Common Human Coronaviruses, United States, 2014–2021

Emerging Infectious Diseases, 2022
The 4 common types of human coronaviruses (HCoVs)—2 alpha (HCoV-NL63 and HCoV-229E) and 2 beta (HCoV-HKU1 and HCoV-OC43)—generally cause mild upper respiratory illness.
Melisa M. Shah, Amber Winn, Rebecca M. Dahl, Krista L. Kniss, Benjamin J. Silk, Marie E. Killerby   +5 more
doaj   +1 more source

COVID-19: perspectivas terapéuticas en IL-17/Th17

Iatreia, 2021
Las células T helper-17 (Th17) y la interleuquina (IL) IL-17 desempeñan funciones biológicas relacionadas con la protección contra infecciones por bacterias extracelulares y hongos.
Franky Úsuga-Úsuga, Luis F. García, Margarita María Velásquez-Lopera   +2 more
doaj   +1 more source

COVID-19: a perspective focus on IL-17/Th17

Iatreia, 2022
Interleukin 17 (IL-17)-producing helper T cells (Th17) and IL-17 play an important role in the defense against extracellular bacteria and fungi; however, persistent secretion of IL-17 is also an important component in the pathogenesis of many ...
Úsuga-Úsuga, Franky , García, Luis F., Velásquez-Lopera, Margarita   +2 more
doaj   +1 more source

Multiple Early Introductions of SARS-CoV-2 to Cape Town, South Africa

Viruses, 2021
Cape Town was the first city in South Africa to experience the full impact of the coronavirus disease 2019 (COVID-19) pandemic. We acquired samples from all suspected cases and their contacts during the first month of the pandemic from Tygerberg Hospital.
Susan Engelbrecht, Kayla Delaney, Bronwyn Kleinhans, Eduan Wilkinson, Houriiyah Tegally, Tania Stander, Gert van Zyl, Wolfgang Preiser, Tulio de Oliveira   +8 more
doaj   +1 more source

Development of a Biosensor Based on Angiotensin‐Converting Enzyme II for Severe Acute Respiratory Syndrome Coronavirus 2 Detection in Human Saliva

Frontiers in Sensors, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the novel coronavirus responsible for COVID-19. Infection in humans requires angiotensin-converting enzyme II (hACE2) as the point of entry for SARS-CoV-2.
Geisianny Moreira, Geisianny Moreira, Lisseth Casso-Hartmann, Shoumen Palit Austin Datta, Shoumen Palit Austin Datta, Delphine Dean, Delphine Dean, Eric McLamore, Eric McLamore, Eric McLamore, Diana Vanegas, Diana Vanegas   +11 more
doaj   +1 more source

The Pro-Inflammatory Chemokines CXCL9, CXCL10 and CXCL11 Are Upregulated Following SARS-CoV-2 Infection in an AKT-Dependent Manner

Viruses, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible RNA virus that is the causative agent of the Coronavirus disease 2019 (COVID-19) pandemic.
Victoria Callahan, Seth Hawks, Matthew A. Crawford, Caitlin W. Lehman, Holly A. Morrison, Hannah M. Ivester, Ivan Akhrymuk, Niloufar Boghdeh, Rafaela Flor, Carla V. Finkielstein, Irving Coy Allen, James Weger-Lucarelli, Nisha Duggal, Molly A. Hughes, Kylene Kehn-Hall   +14 more
doaj   +1 more source